...Yunlong Lei; Kui Wang; Xuefeng Li; Yi Li; Xuping Feng; Jing Zhou; Zhe Zhang; Canhua Huang; Tao Zhang Bleomycin, a widely used anti-cancer drug, may give rise to pulmonary fibrosis, a serious side effect which is associated with significant morbidity and mortality. Despite the intensive efforts...

... driving enhanced cough may help us to define better therapies for patients. We hypothesized that lung fibrosis induced by intratracheal bleomycin would exacerbate the cough reflex induced by tussive agents in guinea pigs. Disease progression in the lungs was characterized at days 1, 7, 14, 21 and 28 after...

.... 25 3 1991 11 4 1991 © 1991 The Biochemical Society and the Medical Research Society 1991 antioxidant bleomycin caeruloplasmin lipid peroxidation oxygen radicals vitamin C supplementation Clinical Science (1991) 81, 413-417 413 Plasma ascorbate levels and inhibition...

...A. W. Segal; G. Gregoriadis; J. P. Lavender; D. Tarin; T. J. Peters 1. Liposomes containing 111 In-labelled bleomycin were injected intravenously into two patients. One patient had a hepatoma and the other had secondary adenocarcinomatous deposits in the liver. 2. The tissue distribution of 111...