...Ingunn Holen; Claire M. Shipman OPG (osteoprotegerin), a secreted member of the TNF (tumour necrosis factor) receptor superfamily, has a variety of biological functions which include the regulation of bone turnover. OPG is a potent inhibitor of osteoclastic bone resorption and has been investigated...

...Anna Daroszewska; Stuart H. Ralston PDB (Paget's disease of bone) is a common condition characterized by focal increases in bone turnover affecting one or more sites throughout the skeleton. Genetic factors are important in the pathogenesis of PDB and many families have been described where PDB...

... alteration induced by the lack of gonadal hormones but unrelated to bone turnover cannot be excluded. 14 5 1992 27 5 1992 © 1992 The Biochemical Society and the Medical Research Society 1992 bone turnover interleukin-1 interleukin-6 mononuclear cells oophorectomy Clinical...

... of hydroxyproline. 3. Histological examination of trabecular bone showed an increase in bone turnover and the bone formation rate increased twofold ( P < 0.02). There were no significant changes in bone volume or wall thickness after treatment. Tetracycline labelling was used to discriminate bone structural...