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Keywords: bortezomib
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Clin Sci (Lond) (2021) 135 (1): 53–69.
Published: 05 January 2021
...–mesenchymal transition. Bortezomib has been reported to prevent the progression of fibrosis in organs. We used rat renal transplantation model and human kidney 2 cell line treated with tumor necrosis factor-α (TNF-α) to examine their response to bortezomib. To explore the mechanism behind it, we assessed the...
Includes: Supplementary data
Clin Sci (Lond) (2019) 133 (16): 1827–1844.
Published: 27 August 2019
... were further supported by several in vitro studies on immature cardiomyocytes. In the present study, we investigated the toxicity of clinically used PIs alone (bortezomib (BTZ), carfilzomib (CFZ)) as well as their combinations with an ANT (daunorubicin (DAU)) in both neonatal and adult ventricular...
Includes: Supplementary data