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Keyword: brain natriuretic peptide
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Articles
Clin Sci (Lond) (2009) 116 (3): 257–263.
Published: 08 January 2008
... failure). Interpretation of BNP (brain natriuretic peptide) and NTproBNP (N-terminal pro-BNP) levels is multifaceted as their secretion is influenced by many variables. A newly identified glycopeptide called copeptin is comparable with the natriuretic peptides in the diagnosis and prognosis of HF and as a...
Articles
Clin Sci (Lond) (2007) 112 (9): 485–491.
Published: 02 April 2007
... to nitroprusside-induced hypotension. However, compared with the rise observed on the control day, plasma ANP (atrial natriuretic peptide; P =0.043), BNP (brain natriuretic peptide; P =0.038) and endothelin-1 ( P =0.011) levels were reduced following Ucn1 administration. Associated with this...
Articles
Clin Sci (Lond) (2005) 108 (1): 23–36.
Published: 15 December 2004
...Miriam T. RADEMAKER; A. Mark RICHARDS The cardiac natriuretic peptides, ANP (atrial natriuretic peptide) and BNP (brain natriuretic peptide), are secreted by the heart in proportion to cardiac transmural pressures. They possess a wide range of effects in multiple tissues facilitating overall...
Articles
Clin Sci (Lond) (2003) 104 (3): 303–312.
Published: 17 February 2003
...Hans BENTZEN; Robert S. PEDERSEN; Henrik B. PEDERSEN; Ole NYVAD; Erling B. PEDERSEN The purpose of this study was to clarify whether the secretions of atrial natriuretic peptide (ANP) and brain natriuretic peptide (BNP) are pulsatile in patients with chronic heart failure (CHF), and whether the...
Articles
Clin Sci (Lond) (2002) 103 (5): 493–499.
Published: 10 October 2002
... natriuretic peptide and brain natriuretic peptide (BNP). The Sphygmocor derivation of the central aortic pulse wave was used to measure time for transmission of the reflected wave (T R ) and the augmentation index (AI), which is the proportional increase in systolic pressure due to the reflected wave. There...
Articles
Clin Sci (Lond) (2002) 103 (s2002): 249S–253S.
Published: 01 September 2002
... ratio of the second messenger cGMP to plasma concentrations of ANP or brain natriuretic peptide (BNP) correlates with the effectiveness of natriuretic peptides. It was investigated whether blockade of the ET A receptor might improve the cGMP:NP ratio in heart failure. Patients with chronic heart failure...
Articles
Clin Sci (Lond) (1999) 97 (3): 255–258.
Published: 15 July 1999
...P. F. DOWNIE; S. TALWAR; I. B. SQUIRE; J. E. DAVIES; D. B. BARNETT; L. L. NG Plasma concentrations of N-terminal pro-brain natriuretic peptide (NT-proBNP) are raised in patients with left ventricular dysfunction. Measurement of this peptide has a potential diagnostic role in the identification and...
Articles
Clin Sci (Lond) (1999) 97 (2): 201–206.
Published: 29 June 1999
...Erling B. PEDERSEN; Henrik B. PEDERSEN; Kaare T. JENSEN Both atrial natriuretic peptide (ANP) and brain natriuretic peptide (BNP) are involved in sodium and water homoeostasis in healthy humans. The plasma concentrations of the natriuretic peptides can be used to differentiate between dyspnoea of...
Articles
Clin Sci (Lond) (1999) 96 (4): 373–380.
Published: 01 April 1999
...D. HUGHES; S. TALWAR; I. B. SQUIRE; J. E. DAVIES; L. L. NG Measurement of plasma levels of brain natriuretic peptide (BNP) has been used to assess left ventricular dysfunction and prognosis. Levels of the N-terminus of the precursor of BNP (NT-proBNP) have been reported to be elevated to a greater...
Articles
Clin Sci (Lond) (1999) 96 (2): 129–136.
Published: 01 February 1999
...Noritoshi NAGAYA; Yoichi GOTO; Toshio NISHIKIMI; Masaaki UEMATSU; Yuji MIYAO; Yoshio KOBAYASHI; Shunichi MIYAZAKI; Seiki HAMADA; Sachio KURIBAYASHI; Makoto TAKAMIYA; Hisayuki MATSUO; Kenji KANGAWA; Hiroshi NONOGI Previous studies have shown that levels of plasma brain natriuretic peptide (BNP...
Articles
Clin Sci (Lond) (1998) 96 (1): 5–15.
Published: 01 January 1999
...Kaare T. JENSEN; Hans EISKJÆR; Jan CARSTENS; Erling B. PEDERSEN The effect of a continuous infusion of human brain natriuretic peptide, 2 ;pmol·min -1 ·kg -1 , during 60 ;min was studied in nine patients with congestive heart failure and in 10 healthy control subjects. Brain natriuretic peptide...
Articles
Clin Sci (Lond) (1998) 95 (6): 701–708.
Published: 01 December 1998
...Christopher J. CHARLES; Eric A. ESPINER; M. Gary NICHOLLS; Miriam T. RADEMAKER; A. Mark RICHARDS 1. The circulating cardiac hormones atrial natriuretic peptide (ANP) and brain natriuretic peptide (BNP) have similar bioactivity, as judged by comparative short-term studies. However, no study has...
Articles
Clin Sci (Lond) (1998) 95 (3): 235–239.
Published: 01 September 1998
... 1998 atrial natriuretic peptide brain natriuretic peptide cardiac function stability room temperature molecular forms 235Clinical Science (1998) 95, 235 239 (Printed in Great Britain) Prolonged stability of brain natriuretic peptide: importance for non-invasive assessment of cardiac...
Articles
Clin Sci (Lond) (1998) 94 (2): 135–139.
Published: 01 February 1998
... adrenomedullin, atrial natriuretic peptide and brain natriuretic peptide in the right atrium, pulmonary artery and aorta. 3. Plasma levels of adrenomedullin in the right atrium (mean ± SEM) were significantly increased on admission (4.2 ± 2.6 h) in patients with acute myocardial infarction (10.6 ± 1.0 pmol/l...
Articles
Clin Sci (Lond) (1998) 94 (1): 21–28.
Published: 01 January 1998
... antibody. Plasma levels of endothelin-1, atrial and brain natriuretic peptides and noradrenaline were also measured. 3. Plasma levels of adrenomedullin were higher in patients with hypertrophic cardiomyopathy (8.43 ± 3.73 pmol/l) than in normal controls (5.24 ± 0.44 pmol/l, P < 0.005). There was no...
Articles
Clin Sci (Lond) (1997) 92 (3): 255–260.
Published: 01 March 1997
...C. M. Florkowski; A. M. Richards; E. A. Espiner; T. G. Yandle; E. Sybertz; C. M. Frampton 1. To assess the threshold dose for bioactivity of brain natriuretic peptide and the role of endopeptidase 24.11 in metabolism of brain natriuretic peptide at physiological plasma levels, we studied eight...
Articles
Clin Sci (Lond) (1996) 90 (3): 197–204.
Published: 01 March 1996
...Hideo Kawakami; Hideki Okayama; Mareomi Hamada; Kunio Hiwada 1. We assessed the changes of atrial natriuretic peptide and brain natriuretic peptide gene expression associated with progression and regression of cardiac hypertrophy in renovascular hypertensive rats (RHR). 2. Two-kidney, one-clip...
Articles
Clin Sci (Lond) (1995) 88 (5): 551–556.
Published: 01 May 1995
...Kazumasa Marumoto; Mareomi Hamada; Kunio Hiwada 1. This study was conducted to assess the role of atrial and brain natriuretic peptides during acute myocardial ischaemia associated with dynamic exercise. 2. Study subjects consisted of 35 angiographically proven patients with angina pectoris and 35...
Articles
Clin Sci (Lond) (1995) 88 (2): 159–164.
Published: 01 February 1995
...Peter B. M. Clarkson; Nigel M. Wheeldon; Catherine MacLeod; Wendy Coutie; Thomas M. MacDonald 1. Elevated plasma concentrations of brain natriuretic peptide are found in conditions associated with impaired left ventricular diastolic function. The purpose of this study was to determine whether this...
Articles
Clin Sci (Lond) (1995) 88 (1): 81–86.
Published: 01 January 1995
...Robert I. Cargill; Allan D. Struthers; Brian J. Lipworth 1. Atrial natriuretic peptide and brain natriuretic peptide have similar vasodilator and natriuretic properties, although little information is available regarding their relative effects as antagonists of the renin—angiotensin—aldosterone...
Articles
Clin Sci (Lond) (1994) 87 (6): 671–677.
Published: 01 December 1994
...Pierre-Louis Tharaux; Jean-Claude Dussaule; Jérôme Hubert-Brierre; Alec Vahanian; Jean Acar; Raymond Ardaillou 1. In order to appreciate the effect of changes in left atrial pressure on plasma brain natriuretic peptide, 20 patients with mitral stenosis treated by percutaneous valvulotomy were...
Articles
Clin Sci (Lond) (1994) 87 (6): 679–684.
Published: 01 December 1994
...John C. Corboy; Robert J. Walker; Mark B. Simmonds; Gerard T. Wilkins; A. Mark Richards; Eric A. Espiner 1. Plasma levels of atrial natriuretic peptide (ANP) and brain natriuretic peptides (BNP) were measured, along with left and right atrial and left ventricular volumes, in eight patients with...
Articles
Clin Sci (Lond) (1994) 87 (3): 319–322.
Published: 01 September 1994
...-type natriuretic peptide levels were compared with the levels of atrial natriuretic peptide and brain natriuretic peptide. 3. Plasma immunoreactive C-type natriuretic peptide concentrations were greatly elevated in patients with chronic renal failure [non-dialysed, 13.0 ± 4.2 pmol/l (mean ± SEM), n = 9...
Articles
Clin Sci (Lond) (1994) 86 (6): 723–730.
Published: 01 June 1994
...B. M. Y. Cheung; J. E. C. Dickerson; M. J. Ashby; M. J. Brown; J. Brown 1. Brain natriuretic peptide, closely related to atrial natriuretic peptide in structure, may be an important circulating hormone. Its physiological role is unclear. First, we studied the effects of incremental infusions of...
Articles
Clin Sci (Lond) (1993) 85 (4): 411–416.
Published: 01 October 1993
...Giorgio La Villa; Silvio Vena; Alberto Conti; Caterina Fronzaroli; Aldo Brat; Chiara Lazzeri; Cristina Tosti Guerra; Stefania Madiai; Nazzareno Marra; Franco Franchi 1. To examine whether posture-induced changes in central volume affect brain natriuretic peptide secretion, plasma levels of human...
Articles
Clin Sci (Lond) (1992) 83 (5): 529–533.
Published: 01 November 1992
...Chim C. Lang; Wendy J. Coutie; Allan D. Struthers; D. Paul Dhillon; John H. Winter; Brian J. Lipworth 1. Studies in vitro have recently shown that both atrial natriuretic peptide and brain natriuretic peptide have pulmonary vasorelaxant activity. The purpose of the present study was to evaluate for...
Articles
Clin Sci (Lond) (1992) 83 (5): 519–527.
Published: 01 November 1992
...Chim C. Lang; Anna-Maria J. Choy; Allan D. Struthers © 1992 The Biochemical Society and the Medical Research Society 1992 atrial natriuretic peptide brain natriuretic peptide blood pressure congestive heart failure sodium excretion Clinical Science (1992) 83, 519-527 (Printed in...
Articles
Clin Sci (Lond) (1992) 83 (4): 437–444.
Published: 01 October 1992
...M. G. Buckley; D. Sethi; N. D. Markandu; G. A. Sagnella; D. R. J. Singer; G. A. MacGregor 1. We have developed a radioimmunoassay for the measurement of immunoreactive brain natriuretic peptide (1–32) in human plasma. Simultaneous measurements of atrial natriuretic peptide have also been carried...
Articles
Clin Sci (Lond) (1992) 83 (2): 143–147.
Published: 01 August 1992
...Chim C. Lang; Joseph G. Motwani; Abdul R. Rahman; Wendy J. Coutie; Allan D. Struthers 1. The aim of this study was to examine the effect of captopril, an angiotensin-converting enzyme inhibitor, on plasma levels of human brain natriuretic peptide-like immunoreactivity (hBNP-li) in patients with...
Articles
Clin Sci (Lond) (1992) 82 (6): 619–623.
Published: 01 June 1992
...Chim C. Lang; Joseph G. Motwani; Wendy J. R. Coutie; Allan D. Struthers 1. Brain natriuretic peptide is a new natriuretic hormone with striking similarity to atrial natriuretic peptide, but there are no previous data concerning its clearance in man. Two pathways of clearance for atrial natriuretic...
Articles
Clin Sci (Lond) (1992) 82 (2): 127–131.
Published: 01 February 1992
...Chim C. Lang; Anna Maria; J. Choy; Iain S. Henderson; Wendy J. Coutie; Allan D. Struthers 1. Plasma human brain natriuretic peptide-like immunoreactivity (hBNP-li) was measured in ten patients with chronic renal failure before and after 4 h of haemodialysis. 2. Plasma hBNP-li was elevated in all...