... their bromosulphthalein kinetics were studied 1 week before the bilirubin test. These results were essentially normal and it was concluded that the hepatic clearance mechanisms for bilirubin and bromosulphthalein are different. 4. In 10 patients the bilirubin transport maximum ( T m ) was found to be low whereas...

...D. V. Datta; Sarban Singh; P. N. Chhuttani; C. R. Nair 1. The roles of the kidney and the small intestine in the conjugation of bromosulphthalein have been compared with that of the liver. 2. Studies with homogenates indicated that the liver has a higher bromosulphthalein—glutathione-conjugating...

...M. J. Clarkson; Anne Hardy-Smith; T. G. Richards 1. A method is described for the measurement of liver blood flow without hepatic venous catheterization by the injection of a single dose of bromosulphthalein and the analysis of the graph of the plasma disappearance of the indicator. 2...

...M. Davis; G. Ideo; N. G. Harrison; R. Williams 1. Plasma clearance of bromosulphthalein was impaired in patients within 8 h, and in rats within 2 h, of paracetamol overdose, before biochemical signs of liver damage had appeared. 2. Paracetamol and bromosulphthalein competed for uptake...