1-1 of 1
Keywords: cGKI
Close
Save search
Follow your search
Access your saved searches in your account
Would you like to receive an alert when new items match your search?
Close Modal
Sort by
Articles

Angiotensin II-induced cardiac fibrosis and dysfunction are exacerbated by deletion of cGKI in periostin + myofibroblasts

Open Access
Melanie Cruz Santos, Lena Birkenfeld, Thomas Pham, Selina Maier, Katharina Paulus, Lena Ullemeyer, Amelie Knauer, Clement Kabagema-Bilan, Natalie Längst, Anna Roslan, Nina Wettschureck, Meinrad Gawaz, Fumito Ichinose, Robert Lukowski
Journal: Clinical Science
Clin Sci (Lond) (2025) 139 (11): 507–526.
https://doi.org/10.1042/CS20241204
Published: 28 May 2025
... stiffness. Although previous studies provided substantial evidence for the antifibrotic signaling elicited by NO/NP-cGMP-cGKI, the role of this axis in modulating CMF function(s) in vivo remains unclear. To address this, Ang II was delivered through osmotic minipumps into tamoxifen-induced CMF-specific cGKI...
View articletitled, Angiotensin II-induced cardiac fibrosis and dysfunction are exacerbated by deletion of cGKI in periostin + myofibroblasts
Open the PDF for Angiotensin II-induced cardiac fibrosis and dysfunction are exacerbated by deletion of cGKI in periostin + myofibroblasts in another window
Includes: Supplementary data