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Keywords: cardiac fibrosisClose
Sarah R. Anthony, Adrienne R. Guarnieri, Anamarie Gozdiff, Robert N. Helsley, Albert Phillip Owens, III, Michael Tranter
Clin Sci (Lond) (2019) 133 (22): 2329–2344.
Published: 28 November 2019
...(s). Published by Portland Press Limited on behalf of the Biochemical Society 2019 adipokines brown adipose tissue cardiac fibrosis cardiac hypertrophy cardiovascular disease obesity Adipose tissue biology is intricately linked to cardiovascular health, and the growing obesity...
Clin Sci (Lond) (2019) 133 (17): 1845–1856.
Published: 10 September 2019
...Kun Yang; Jiaran Shi; Zhujun Hu; Xiaosheng Hu Cardiac fibrosis is a common pathological feature of many cardiovascular diseases. The regulatory mechanisms of miRNAs in cardiac fibrosis are still unknown. Previous studies on miR-214-3p in cardiac fibroblasts reached contradictory conclusions. Thus...
Includes: Supplementary data
Clin Sci (Lond) (2017) 131 (10): 897–915.
Published: 04 May 2017
... Biochemical Society 2017 cardiac fibrosis cardiomyocyte hypertrophy diabetic cardiomyopathy diastolic dysfunction hyperglycaemia The global incidence of diabetes is predicted to reach 642 million adults by 2040, affecting both human health and world economies. Cardiovascular disease is the...
Clin Sci (Lond) (2011) 120 (8): 335–345.
Published: 22 December 2010
... cited. angiotensin peptide cardiac fibrosis kidney failure renal mass reduction renin–angiotensin system Activation of the RAS (renin–angiotensin system) and generation of Ang (angiotensin) II is pivotal for the development and progression of renal disease [ 1 ]. Current treatment...
Clin Sci (Lond) (2009) 116 (9): 731–739.
Published: 02 April 2009
...Peter Wilson; James Morgan; John W. Funder; Peter J. Fuller; Morag J. Young Coronary, vascular and perivascular inflammation in rats following MR (mineralocorticoid receptor) activation plus salt are well-characterized precursors for the appearance of cardiac fibrosis. Endogenous corticosterone, in...
Clin Sci (Lond) (2007) 112 (9): 467–475.
Published: 02 April 2007
... stages of the development of cardiac fibrosis in experimental animals. These studies suggest potential mechanisms for the benefits observed in recent large scale clinical trials investigating the cardioprotective effects of MR antagonists given in conjunction with current best practice therapy for...
Christa THÖNE-REINEKE, Jan OLIVIER, Michael GODES, Rüdiger ZART, Ines GEORGE, Christian BAUER, Hans-Helmut NEUMAYER, Berthold HOCHER
Clin Sci (Lond) (2003) 104 (1): 79–85.
Published: 06 January 2003
... ). 10 10 2002 12 11 2002 The Biochemical Society and the Medical Research Society © 2003 2003 ACE inhibition apoptosis cardiac fibrosis renovascular hypertension. 79Clinical Science (2003) 104, 79 85 (Printed in Great Britain) Effects of angiotensin-converting enzyme inhibition...
Takehiro OGATA, Takashi MIYAUCHI, Satoshi SAKAI, Yoko IRUKAYAMA-TOMOBE, Katsutoshi GOTO, Iwao YAMAGUCHI
Clin Sci (Lond) (2002) 103 (s2002): 284S–288S.
Published: 01 September 2002
... proliferation of fibroblasts and cardiac fibrosis. Peroxisome-proliferator-activated receptor α (PPARα), one of the nuclear hormone receptors, suppresses activator protein-1 (AP-1), one of the nuclear transcription factors. Activation of PPARα is reported to inhibit thrombin-induced ET-1 production by...