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Keywords: cardiac myofibroblasts
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Angiotensin II-induced cardiac fibrosis and dysfunction are exacerbated by deletion of cGKI in periostin + myofibroblasts

Open Access
Melanie Cruz Santos, Lena Birkenfeld, Thomas Pham, Selina Maier, Katharina Paulus, Lena Ullemeyer, Amelie Knauer, Clement Kabagema-Bilan, Natalie Längst, Anna Roslan, Nina Wettschureck, Meinrad Gawaz, Fumito Ichinose, Robert Lukowski
Journal: Clinical Science
Clin Sci (Lond) (2025) 139 (11): 507–526.
https://doi.org/10.1042/CS20241204
Published: 28 May 2025
...; CMF, cardiac myofibroblast; CTR, control; MAP, mean arterial pressure; PP, pulse pressure; TAM, tamoxifen. Figure 2: Ang II provokes greater histopathological changes in cmfKO hearts. (A) Hearts derived from +TAM and +TAM plus Ang II-treated CTR and cmf KO animals were divided into eight...
View articletitled, Angiotensin II-induced cardiac fibrosis and dysfunction are exacerbated by deletion of cGKI in periostin + myofibroblasts
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Includes: Supplementary data