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Keywords: cardiac output
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Articles

G16R single nucleotide polymorphism but not haplotypes of the β 2 -adrenergic receptor gene alters cardiac output in humans

Kim Z. Rokamp, Jonatan M. Staalsoe, Martin Gartmann, Anna Sletgaard, Nicolai B. Nordsborg, Niels H. Secher, Henning B. Nielsen, Niels V. Olsen
Journal: Clinical Science
Clin Sci (Lond) (2013) 125 (4): 191–198.
https://doi.org/10.1042/CS20120555
Published: 01 May 2013
...Kim Z. Rokamp; Jonatan M. Staalsoe; Martin Gartmann; Anna Sletgaard; Nicolai B. Nordsborg; Niels H. Secher; Henning B. Nielsen; Niels V. Olsen Variation in genes encoding the β 2 -adrenergic receptor ( ADRB2 ) and angiotensin-converting enzyme ( ACE ) may influence Q ̇ (cardiac output). The 46G...
View articletitled, G16R single nucleotide polymorphism but not haplotypes of the β 2 -adrenergic receptor gene alters cardiac output in humans
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Articles

Central and cerebrovascular effects of leg crossing in humans with sympathetic failure

Mark P.M. Harms, Wouter Wieling, Willy N.J.M. Colier, Jacques W.M. Lenders, Niels H. Secher, Johannes J. van Lieshout
Journal: Clinical Science
Clin Sci (Lond) (2010) 118 (9): 573–581.
https://doi.org/10.1042/CS20090038
Published: 09 February 2010
... (cardiac output) and TPR (total peripheral resistance) in six patients (aged 37–67 years; three women) and age- and gender-matched controls during leg crossing. In the patients, leg crossing increased MAP from 58 (42–79) to 72 (52–89) compared with 84 (70–95) to 90 (74–94) mmHg in the controls. MCA V mean...
View articletitled, Central and cerebrovascular effects of leg crossing in humans with sympathetic failure
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Articles

Chronic fatigue syndrome: comments on deconditioning, blood volume and resulting cardiac function

Julian M. Stewart
Journal: Clinical Science
Clin Sci (Lond) (2010) 118 (2): 121–123.
https://doi.org/10.1042/CS20090327
Published: 19 October 2009
...Julian M. Stewart Cardiovascular and autonomic dysfunction have been suggested to underlie the symptoms accompanying CFS (chronic fatigue syndrome). In the present issue of Clinical Science , Hurwitz and co-workers have investigated whether deficits were present in cardiac output and blood volume...
View articletitled, Chronic fatigue syndrome: comments on deconditioning, blood volume and resulting cardiac function
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Articles

Chronic fatigue syndrome: illness severity, sedentary lifestyle, blood volume and evidence of diminished cardiac function

Barry E. Hurwitz, Virginia T. Coryell, Meela Parker, Pedro Martin, Arthur LaPerriere, Nancy G. Klimas, George N. Sfakianakis, Martin S. Bilsker
Journal: Clinical Science
Clin Sci (Lond) (2010) 118 (2): 125–135.
https://doi.org/10.1042/CS20090055
Published: 19 October 2009
...Barry E. Hurwitz; Virginia T. Coryell; Meela Parker; Pedro Martin; Arthur LaPerriere; Nancy G. Klimas; George N. Sfakianakis; Martin S. Bilsker The study examined whether deficits in cardiac output and blood volume in a CFS (chronic fatigue syndrome) cohort were present and linked to illness...
View articletitled, Chronic fatigue syndrome: illness severity, sedentary lifestyle, blood volume and evidence of diminished cardiac function
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Articles

Deterioration in cardiac systolic and diastolic function late in normal human pregnancy

Dominica Zentner, Moira du Plessis, Shaun Brennecke, James Wong, Leeanne Grigg, Stephen B. Harrap
Journal: Clinical Science
Clin Sci (Lond) (2009) 116 (7): 599–606.
https://doi.org/10.1042/CS20080142
Published: 02 March 2009
... underwent echocardiography, including tissue Doppler imaging, determining left ventricular mass, cardiac output, systolic and diastolic velocities, and wall stress. A total of 32 were assessed again at a median of 37 weeks of gestation. Non-pregnant control estimates ( n =9) were obtained by averaging four...
View articletitled, Deterioration in cardiac systolic and diastolic function late in normal human pregnancy
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Articles

Administration of brain natriuretic peptide improves cardiac function following operations using extracorporeal circulation in an animal model

Dorothee H. L. Bail, Volker Steger, Uli Heinzelmann, Sandra Schiller, Anita I. Geim, Benjamin Brüllmann, Gerhard Ziemer
Journal: Clinical Science
Clin Sci (Lond) (2007) 112 (5): 315–324.
https://doi.org/10.1042/CS20060136
Published: 01 February 2007
... of catecholamines that were required were measured. All of the animals in the BNP group had a significantly better cardiac output and cardiac index at the end of the experiment. Seven out of 10 animals from the control group required catecholamines, whereas only one animal from the BNP group did. Creatine kinase...
View articletitled, Administration of brain natriuretic peptide improves cardiac function following operations using extracorporeal circulation in an animal model
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Articles

Varying the heart rate response to dynamic exercise in pacemaker-dependent subjects: effects on cardiac output and cerebral blood velocity

Lysander W. J. Bogert, Ayten Erol-Yilmaz, Raymond Tukkie, Johannes J. Van Lieshout
Journal: Clinical Science
Clin Sci (Lond) (2005) 109 (6): 493–501.
https://doi.org/10.1042/CS20050094
Published: 23 November 2005
...Lysander W. J. Bogert; Ayten Erol-Yilmaz; Raymond Tukkie; Johannes J. Van Lieshout Cerebral blood flow increases upon the transition from rest to moderate exercise, but becomes affected when the ability to raise CO (cardiac output) is limited. HR (heart rate) is considered to contribute...
View articletitled, Varying the heart rate response to dynamic exercise in pacemaker-dependent subjects: effects on cardiac output and cerebral blood velocity
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Articles

Cardiac output by Modelflow® method from intra-arterial and fingertip pulse pressure profiles

Marcel AZABJI KENFACK, Federic LADOR, Marc LICKER, Christian MOIA, Enrico TAM, Carlo CAPELLI, Denis MOREL, Guido FERRETTI
Journal: Clinical Science
Clin Sci (Lond) (2004) 106 (4): 365–369.
https://doi.org/10.1042/CS20030303
Published: 01 April 2004
...Marcel AZABJI KENFACK; Federic LADOR; Marc LICKER; Christian MOIA; Enrico TAM; Carlo CAPELLI; Denis MOREL; Guido FERRETTI Modelflow®, when applied to non-invasive fingertip pulse pressure recordings, is a poor predictor of cardiac output (Q, litre·min -1 ). The use of constants established from...
View articletitled, Cardiac output by Modelflow® method from intra-arterial and fingertip pulse pressure profiles
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Articles

Correction of cardiac output obtained by Modelflow® from finger pulse pressure profiles with a respiratory method in humans

Enrico TAM, Marcel AZABJI KENFACK, Michela CAUTERO, Federic LADOR, Guglielmo ANTONUTTO, Pietro Enrico DI PRAMPERO, Guido FERRETTI, Carlo CAPELLI
Journal: Clinical Science
Clin Sci (Lond) (2004) 106 (4): 371–376.
https://doi.org/10.1042/CS20030302
Published: 01 April 2004
...Enrico TAM; Marcel AZABJI KENFACK; Michela CAUTERO; Federic LADOR; Guglielmo ANTONUTTO; Pietro Enrico DI PRAMPERO; Guido FERRETTI; Carlo CAPELLI The beat-by-beat non-invasive assessment of cardiac output (Q, litre·min -1 ) based on the arterial pulse pressure analysis called Modelflow® can...
View articletitled, Correction of cardiac output obtained by Modelflow® from finger pulse pressure profiles with a respiratory method in humans
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Articles

Cardiac output by Portapres®

Marjorie S. PITT, Paul MARSHALL, Jonathan P. DIESCH, Roger HAINSWORTH
Journal: Clinical Science
Clin Sci (Lond) (2004) 106 (4): 407–412.
https://doi.org/10.1042/CS20030279
Published: 01 April 2004
...Marjorie S. PITT; Paul MARSHALL; Jonathan P. DIESCH; Roger HAINSWORTH Portapres® derives continuous estimates of cardiac output from the peripheral pulse and has the potential to be an extremely valuable physiological and clinical tool. We assessed Portapres® estimates of cardiac output in healthy...
View articletitled, Cardiac output by Portapres®
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Articles

Orthostatic challenge reveals impaired vascular resistance control, but normal venous pooling and capillary filtration in familial dysautonomia

Clive M. BROWN, Brigitte STEMPER, Götz WELSCH, Miroslaw BRYS, Felicia B. AXELROD, Max J. HILZ
Journal: Clinical Science
Clin Sci (Lond) (2003) 104 (2): 163–169.
https://doi.org/10.1042/cs1040163
Published: 17 January 2003
... vascular responses to orthostasis have not been assessed. The aim of this study was to evaluate the control of vascular responses to postural stress in FD patients. Measurements of heart rate, blood pressure, cardiac stroke volume and cardiac output (CO), by impedance cardiography, and calf-volume changes...
View articletitled, Orthostatic challenge reveals impaired vascular resistance control, but normal venous pooling and capillary filtration in familial dysautonomia
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Articles

Finapres arterial pulse wave analysis with Modelflow® is not a reliable non-invasive method for assessment of cardiac output

Jaap J. REMMEN, Wim R.M. AENGEVAEREN, Freek W.A. VERHEUGT, Tjeerd VAN DER WERF, Hans E. LUIJTEN, Anja BOS, René W.M.M. JANSEN
Journal: Clinical Science
Clin Sci (Lond) (2002) 103 (2): 143–149.
https://doi.org/10.1042/cs1030143
Published: 28 June 2002
...Jaap J. REMMEN; Wim R.M. AENGEVAEREN; Freek W.A. VERHEUGT; Tjeerd VAN DER WERF; Hans E. LUIJTEN; Anja BOS; René W.M.M. JANSEN Non-invasive continuous monitoring of cardiac output could be very useful in clinical care and in research settings, particularly in elderly subjects. We studied whether...
View articletitled, Finapres arterial pulse wave analysis with Modelflow® is not a reliable non-invasive method for assessment of cardiac output
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Articles

Non-invasive measurement of cardiac output in heart failure patients using a new foreign gas rebreathing technique

Anders GABRIELSEN, Regitze VIDEBÆK, Morten SCHOU, Morten DAMGAARD, Jens KASTRUP, Peter NORSK
Journal: Clinical Science
Clin Sci (Lond) (2002) 102 (2): 247–252.
https://doi.org/10.1042/cs1020247
Published: 14 January 2002
...Anders GABRIELSEN; Regitze VIDEBÆK; Morten SCHOU; Morten DAMGAARD; Jens KASTRUP; Peter NORSK Values of effective pulmonary blood flow ( Q EP ) and cardiac output, determined by a non-invasive foreign gas rebreathing method (CO RB ) using a new infrared photoacoustic gas analysing system, were...
View articletitled, Non-invasive measurement of cardiac output in heart failure patients using a new foreign gas rebreathing technique
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Articles

Haemodynamic and renal evolution of the bile duct-ligated rat

Concepción MARTÍNEZ-PRIETO, M. Clara ORTÍZ, Lourdes A. FORTEPIANI, Jose Antonio RUIZ-MACIÁ, Noemí M. ATUCHA, Joaquín GARCÍA-ESTAÑ
Journal: Clinical Science
Clin Sci (Lond) (2000) 98 (5): 611–617.
https://doi.org/10.1042/cs0980611
Published: 26 April 2000
... 2000 aldosterone arterial pressure cardiac output kidney liver cirrhosis portal pressure renin sodium retention 611Clinical Science (2000) 98, 611 617 (Printed in Great Britain) Haemodynamic and renal evolution of the bile duct-ligated rat Concepcio! n MARTI!NEZ-PRIETO*, M. Clara ORTI!Z...
View articletitled, Haemodynamic and renal evolution of the bile duct-ligated rat
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Articles

Non-invasive measurement of stroke volume during exercise in heart failure patients

Pier Giuseppe AGOSTONI, Karlman WASSERMAN, Giovanni B. PEREGO, Marco GUAZZI, Gaia CATTADORI, Pietro PALERMO, Gianfranco LAURI, Giancarlo MARENZI
Journal: Clinical Science
Clin Sci (Lond) (2000) 98 (5): 545–551.
https://doi.org/10.1042/cs0980545
Published: 04 April 2000
... population-estimated mean values for C (a–v)O 2 in heart failure patients. Correspondence : Dr Agostoni (e-mail [email protected] ). 22 7 1999 19 10 1999 4 1 2000 The Biochemical Society and the Medical Research Society © 2000 2000 cardiac output...
View articletitled, Non-invasive measurement of stroke volume during exercise in heart failure patients
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Articles

Chronic infusions of brain natriuretic peptide in conscious sheep: bioactivity at low physiological levels

Christopher J. CHARLES, Eric A. ESPINER, M. Gary NICHOLLS, Miriam T. RADEMAKER, A. Mark RICHARDS
Journal: Clinical Science
Clin Sci (Lond) (1998) 95 (6): 701–708.
https://doi.org/10.1042/cs0950701
Published: 01 December 1998
... within the physiological range (4 pmol/l increment, P < 0.001) and increased cyclic GMP levels ( P = 0.01). BNP infusions induced significant falls in right atrial pressure ( P = 0.048), stroke volume ( P = 0.014) and cardiac output ( P = 0.003) associated with a rise in haematocrit ( P = 0.001...
View articletitled, Chronic infusions of brain natriuretic peptide in conscious sheep: bioactivity at low physiological levels
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Articles

Renal haemodynamics, sodium and water reabsorption during continuous intravenous infusion of recombinant interleukin-2

Poul F. GEERTSEN, Hans VON DER MAASE, Niels Vidiendal OLSEN, Niels FOGH-ANDERSEN, Steen Levin NIELSEN, Paul P. LEYSSAC
Journal: Clinical Science
Clin Sci (Lond) (1998) 95 (1): 73–81.
https://doi.org/10.1042/cs0950073
Published: 01 July 1998
... studied before and after 72 h of continuous intravenous infusion of recombinant interleukin-2 (18×10 6 i.u.·24 h -1 ·m -2 ) and 48 h post therapy. Cardiac output was measured by impedance cardiography. Effective renal plasma flow and glomerular filtration rate were determined by the renal clearances...
View articletitled, Renal haemodynamics, sodium and water reabsorption during continuous intravenous infusion of recombinant interleukin-2
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Articles

Increased Nitric Oxide Synthesis and Inducible Nitric Oxide Synthase Expression in Patients with Alcoholic and Non-Alcoholic Liver Cirrhosis

A. Sánchez-Rodríguez, M. Criado, A. M. Rodríguez-López, A. Esteller, A. Martín De Arriba, J. M. López-Novoa
Journal: Clinical Science
Clin Sci (Lond) (1998) 94 (6): 637–643.
https://doi.org/10.1042/cs0940637
Published: 01 June 1998
... clinical and histological criteria in non-alcoholic cirrhotic, alcoholic cirrhotic and non-cirrhotic chronic liver disease. We studied clinical and analytical characteristics, haemodynamic parameters and endotoxin levels in these patients. 3. Cirrhotic patients showed an increase of cardiac output...
View articletitled, Increased Nitric Oxide Synthesis and Inducible Nitric Oxide Synthase Expression in Patients with Alcoholic and Non-Alcoholic Liver Cirrhosis
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Articles

Dynamics of Circulatory Adjustments to Head-Up Tilt and Tilt-Back in Healthy and Sympathetically Denervated Subjects

W. Wieling, J. J. Van Lieshout, A. D. J. Ten Harkel
Journal: Clinical Science
Clin Sci (Lond) (1998) 94 (4): 347–352.
https://doi.org/10.1042/cs0940347
Published: 01 April 1998
... and cardiac output had decreased by 39 ± 9% and 26 ± 10% respectively. Little change in mean blood pressure at heart level (+1 ± 7 mmHg) indicated that systemic vascular resistance had increased by 39 ± 24%. The gradual responses to head-up tilt contrasted with the pronounced and rapid circulatory responses...
View articletitled, Dynamics of Circulatory Adjustments to Head-Up Tilt and Tilt-Back in Healthy and Sympathetically Denervated Subjects
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Articles

Influences on Adrenaline-Induced Thermogenesis in Obese Women and Relationship to Cardiovascular Responses

Kevin M. Walsh, Calam Adams, Annemarie Sinclair, Eddie Leen, Michael E. J. Lean
Journal: Clinical Science
Clin Sci (Lond) (1998) 94 (2): 121–127.
https://doi.org/10.1042/cs0940121
Published: 01 February 1998
.... Thermogenic responses were related to body morphology, age and biochemistry. In addition, thermogenic responses were related to cardiovascular responses by simultaneously measuring blood pressure, pulse rate and cardiac output using Doppler sonography. 3. Resting energy expenditure was predicted by body...
View articletitled, Influences on Adrenaline-Induced Thermogenesis in Obese Women and Relationship to Cardiovascular Responses
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Articles

Non-invasive Measurement of Cardiac Output and Ventricular Ejection Fractions in Chronic Cardiac Failure: Relationship to Impaired Exercise Tolerance

Ian C. Steele, ANN Moore, Anne-Marie Nugent, Marshall S. Riley, Norman P. S. Campbell, D. Paul Nicholls
Journal: Clinical Science
Clin Sci (Lond) (1997) 93 (3): 195–203.
https://doi.org/10.1042/cs0930195
Published: 01 September 1997
...Ian C. Steele; ANN Moore; Anne-Marie Nugent; Marshall S. Riley; Norman P. S. Campbell; D. Paul Nicholls 1. The role of cardiac output limitation in the pathophysiology of exercise in patients with chronic failure remains undefined. During steady-state submaximal exercise, oxygen uptake is similar...
View articletitled, Non-invasive Measurement of Cardiac Output and Ventricular Ejection Fractions in Chronic Cardiac Failure: Relationship to Impaired Exercise Tolerance
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Articles

Variability of Near-Fainting Responses in Healthy 6–16-Year-old Subjects

C.E. Catherine, de Jong-de Vos van Steenwijk, Wouter Wieling, Mark P. M. Harms, Karel H. Wesseling
Journal: Clinical Science
Clin Sci (Lond) (1997) 93 (3): 205–211.
https://doi.org/10.1042/cs0930205
Published: 01 September 1997
... responses on approach of an orthostatic faint is wide in the young. 8 1 1997 20 5 1997 © 1997 The Biochemical Society and the Medical Research Society 1997 cardiac output hypotension orthostasis syncope teenagers vasomotor system Clinical Science (1997) 93,205-21 I (Printed...
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Articles

Haemodynamic Effects of Eating: The Role of Meal Composition

U. Høst, H. Kelbaek, H. Rasmusen, M. Court-Payen, N. Juel Christensen, U. Pedersen-Bjergaard, T. Lorenzen
Journal: Clinical Science
Clin Sci (Lond) (1996) 90 (4): 269–276.
https://doi.org/10.1042/cs0900269
Published: 01 April 1996
...-labelled erythrocytes was performed for assessment of cardiac output, venous occlusion plethysmography to obtain forearm blood flow and Doppler-ultrasonography for portal vein flow. Plasma levels of catecholamines and insulin were determined by radioimmunoassay. 3. Cardiac output increased considerably...
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Articles

Effects of Dobutamine on the Relationship between Oxygen Consumption and Delivery in Healthy Volunteers: Comparison with Sodium Nitroprusside

Daniel De Backer, Jacques Berre, Jean Jacques Moraine, Christian Melot, Jacques Vanfraechem, Jean-Louis Vincent
Journal: Clinical Science
Clin Sci (Lond) (1996) 90 (2): 105–111.
https://doi.org/10.1042/cs0900105
Published: 01 February 1996
... volunteers. 2. Eight healthy volunteers received infusions of dobutamine at doses of 2, 4 and 6 μg min −1 kg −1 and nitroprusside at doses of 0.5, 1 and 2 μg min −1 kg −1 in an alternate order. 3. V O 2 was determined by indirect calorimetry and cardiac output by electrical bioimpedance. Data were analysed...
View articletitled, Effects of Dobutamine on the Relationship between Oxygen Consumption and Delivery in Healthy Volunteers: Comparison with Sodium Nitroprusside
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Articles

Effects of Leg Muscle Pumping and Tensing on Orthostatic Arterial Pressure: A Study in Normal Subjects and Patients with Autonomic Failure

A. D. J. Ten Harkel, J. J. Van Lieshout, W. Wieling
Journal: Clinical Science
Clin Sci (Lond) (1994) 87 (5): 553–558.
https://doi.org/10.1042/cs0870553
Published: 01 November 1994
... (aged 20–65 years). 2. Finger arterial pressure was monitored. Relative changes in left ventricular stroke volume were computed by a pulse contour method. 3. Tiptoeing increased mean arterial pressure (7 ± 5 mmHg) in the healthy subjects, but not in the patients, whereas cardiac output increased in both...
View articletitled, Effects of Leg Muscle Pumping and Tensing on Orthostatic Arterial Pressure: A Study in Normal Subjects and Patients with Autonomic Failure
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Articles

Haemodynamic and Neurohumoral Changes in Spontaneously Hypertensive Rats with Aortocaval Fistulae

Tamiko Oka, Hikaru Nishimura, Masakuni Ueyama, Jiro Kubota, Keishiro Kawamura
Journal: Clinical Science
Clin Sci (Lond) (1993) 84 (5): 531–535.
https://doi.org/10.1042/cs0840531
Published: 01 May 1993
... heart failure. © 1993 The Biochemical Society and the Medical Research Society 1993 cardiac hypertrophy cardiac output laser-Doppler flowmetry renal function thermodilution Clinical Science (1993) 84, 531-535 (Printed in Great Britain) Haemodynamic and neurohumoral changes...
View articletitled, Haemodynamic and Neurohumoral Changes in Spontaneously Hypertensive Rats with Aortocaval Fistulae
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Articles

Cardiovascular responses to a high-fat and a high-carbohydrate meal in healthy elderly subjects

M. B. Sidery, A. J. Cowley, I. A. MacDonald
Journal: Clinical Science
Clin Sci (Lond) (1993) 84 (3): 263–270.
https://doi.org/10.1042/cs0840263
Published: 01 March 1993
...M. B. Sidery; A. J. Cowley; I. A. MacDonald 1. The cardiovascular responses to high-fat and high-carbohydrate meals (2.5 MJ) were compared in healthy, non-obese elderly subjects (mean age 68 years, range 63–74 years). 2. Measurements of cardiac output, blood pressure, heart rate, calf blood flow...
View articletitled, Cardiovascular responses to a high-fat and a high-carbohydrate meal in healthy elderly subjects
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Articles

Relative effects of fat-, carbohydrate- and protein-containing liquid diets on cardiac output in healthy adult subjects

Susan K. Hawley, Kevin S. Channer
Journal: Clinical Science
Clin Sci (Lond) (1992) 83 (4): 483–487.
https://doi.org/10.1042/cs0830483
Published: 01 October 1992
...Susan K. Hawley; Kevin S. Channer 1. Nine healthy adult subjects consumed four types of proprietary liquid diet of similar volume and calorific value but of different nutritional composition. The effects on resting cardiac output, mean blood pressure and pulse rate were measured. 2. A significant...
View articletitled, Relative effects of fat-, carbohydrate- and protein-containing liquid diets on cardiac output in healthy adult subjects
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Articles

Analysis of factors limiting maximal exercise performance in cystic fibrosis

Larry C. Lands, George J. F. Heigenhauser, Norman L. Jones
Journal: Clinical Science
Clin Sci (Lond) (1992) 83 (4): 391–397.
https://doi.org/10.1042/cs0830391
Published: 01 October 1992
... cardiac output lean body mass maximal O 2 uptake muscle ventilation Clinical Science (1992) 83, 391-397 (Printed in Great Britain) Analysis of factors limiting m imal exercise performance in cystic fibrosis Larry C. LANDS, George J. F. HEIGENHAUSER and Norman L. JONES Ambrose Cardiorespiratory...
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Articles

Disparities in circulatory adjustment to standing between young and elderly subjects explained by pulse contour analysis

W. Wieling, D. P. Veerman, J. H. A. Dambrink, B. P. M. Imholz
Journal: Clinical Science
Clin Sci (Lond) (1992) 83 (2): 149–155.
https://doi.org/10.1042/cs0830149
Published: 01 August 1992
... in blood pressure. ageing cardiac output heart rate non-invasive continuous blood pressure orthostatic hypotension postural changes stroke volume total peripheral resistance Clinical Science (1992) 83, 149-155 (Printed in Great Britain) Disparities in circulatory adjustment to standing between...
View articletitled, Disparities in circulatory adjustment to standing between young and elderly subjects explained by pulse contour analysis
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Articles

Effects of l-arginine on systemic and renal haemodynamics in conscious dogs

Marohito Murakami, Hiromichi Suzuki, Atsuhiro Ichihara, Mareo Naitoh, Hidetomo Nakamoto, Takao Saruta
Journal: Clinical Science
Clin Sci (Lond) (1991) 81 (6): 727–732.
https://doi.org/10.1042/cs0810727
Published: 01 December 1991
.... 2. Mean arterial blood pressure, heart rate and cardiac output were not changed significantly by l -arginine infusion. However, l -arginine infusion induced a significant elevation of renal blood flow from 50 ± 3 to 94 ± 12 ml/min (means ± sem , P < 0.01). 3. Simultaneous infusion of N G...
View articletitled, Effects of l-arginine on systemic and renal haemodynamics in conscious dogs
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Articles

Reduced oxygen consumption induced by vasopressin in dogs depends on systemic administration

Jean-Francois Liard
Journal: Clinical Science
Clin Sci (Lond) (1991) 81 (6): 751–758.
https://doi.org/10.1042/cs0810751
Published: 01 December 1991
...-' while the animals were breathing 10% oxygen. Hypoxaemia alone (arterial partial Key words: antidiuretic hormone, cardiac output, hypoxia, metabolism, oxygen consumption, regional blood flows. pressure of oxygen 4.67 kPa) decreased whole-body oxygen delivery by 30%. The fall in whole-body oxygen...
View articletitled, Reduced oxygen consumption induced by vasopressin in dogs depends on systemic administration
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Articles

Effect of Endothelin on the Function of the Isolated Perfused Working Rat Heart

J. D. Firth, A. F. C. Roberts, A. E. G. Raine
Journal: Clinical Science
Clin Sci (Lond) (1990) 79 (3): 221–226.
https://doi.org/10.1042/cs0790221
Published: 01 September 1990
...J. D. Firth; A. F. C. Roberts; A. E. G. Raine 1. The effect of endothelin on the performance of the isolated perfused working rat heart has been examined. 2. A low concentration of endothelin (60 pmol/l) produced a gradual but sustained increase in cardiac output; coronary vascular resistance...
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Articles

Haemodynamic and Metabolic Effects of Infused Adenosine in Man

Anders Edlund, Alf Sollevi, Birgitta Linde
Journal: Clinical Science
Clin Sci (Lond) (1990) 79 (2): 131–138.
https://doi.org/10.1042/cs0790131
Published: 01 August 1990
...Anders Edlund; Alf Sollevi; Birgitta Linde 1. Haemodynamic and metabolic effects of intravenous infusion of adenosine, an endogenous vasodilator, were studied in healthy humans. 2. Catheters were inserted into pulmonary and brachial arteries and into the hepatic and subclavian veins. Cardiac output...
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Articles

Cardiac output and oxygen uptake in patients with renal failure

C. H. Kong, F. D. Thompson, F. J. Imms
Journal: Clinical Science
Clin Sci (Lond) (1990) 78 (6): 591–596.
https://doi.org/10.1042/cs0780591
Published: 01 June 1990
... cardiography, are accurate. © 1990 The Biochemical Society and the Medical Research Society 1990 cardiac output oxygen uptake renal failure Clinical Science (1990) 78, 591-596 591 Cardiac output and oxygen uptake in patients with renal failure C. H. KONG, F. D. THOMPSON AND F. J. MMS* Institute...
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Articles

Cardiovascular Reflex Responses in Patients with Unexplained Syncope

M. M. A. E. Wahbha, C. A. Morley, Y. M. H. Al-Shamma, R. Hainsworth
Journal: Clinical Science
Clin Sci (Lond) (1989) 77 (5): 547–553.
https://doi.org/10.1042/cs0770547
Published: 01 November 1989
... responses of blood pressure, heart rate and cardiac output to head-up tilting were determined in 67 patients using entirely ‘non-invasive’ methods. In some patients we also studied the immediate response of pulse interval to carotid baroreceptor stimulation by neck suction. 3. Two of the patients developed...
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Articles

Single-breath breath-holding estimate of pulmonary blood flow in man: comparison with direct Fick cardiac output

A. H. Kendrick, A. Rozkovec, M. Papouchado, J. West, G. Laszlo
Journal: Clinical Science
Clin Sci (Lond) (1989) 76 (6): 673–676.
https://doi.org/10.1042/cs0760673
Published: 01 June 1989
...A. H. Kendrick; A. Rozkovec; M. Papouchado; J. West; G. Laszlo 1. Resting pulmonary blood flow ( Q . ), using the uptake of the soluble inert gas Freon-22 and an indirect estimate of lung tissue volume, has been estimated during breath-holding ( Q . c ) and compared with direct Fick cardiac output...
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Articles

Cardiovascular responses to stimulation of carotid baroreceptors in healthy subjects

R. Hainsworth, Y. M. H. Al-Shamma
Journal: Clinical Science
Clin Sci (Lond) (1988) 75 (2): 159–165.
https://doi.org/10.1042/cs0750159
Published: 01 August 1988
... mmHg, expressed as two standard deviations of the differences between responses on two occasions, were (mean responses in parentheses): immediate pulse interval, ± 32 (+ 236) ms; steady-state heart rate, ± 2.5 (− 6.5) beats/min; cardiac output ± 0.14 (− 0.59) 1/min; systolic and diastolic blood...
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Articles

Cardiovascular responses to upright tilting in healthy subjects

R. Hainsworth, Y. M. H. Al-Shamma
Journal: Clinical Science
Clin Sci (Lond) (1988) 74 (1): 17–22.
https://doi.org/10.1042/cs0740017
Published: 01 January 1988
...R. Hainsworth; Y. M. H. Al-Shamma 1. The cardiovascular responses to passive upright tilting were determined in healthy human subjects of various ages using entirely ‘non-invasive’ techniques. Cardiac output was determined by a single breath method and arterial blood pressure by an automatic...
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Articles

Haemodynamic changes in man during immersion in water at different temperatures

C. F. M. Weston, J. P. O'Hare, J. M. Evans, R. J. M. Corrall
Journal: Clinical Science
Clin Sci (Lond) (1987) 73 (6): 613–616.
https://doi.org/10.1042/cs0730613
Published: 01 December 1987
...C. F. M. Weston; J. P. O'Hare; J. M. Evans; R. J. M. Corrall 1. Stroke volume and cardiac output were measured using the Doppler ultrasound technique in 16 normal subjects immersed to the neck in water at 33°C, 35°C, 37°C and 39°C. A standard aortic diameter was assumed and results were expressed...
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Articles

Haemodynamic consequences of experimental papillary necrosis in the rat

Gavin I. Russell, Robert F. Bing, Herbert Thurston, John D. Swales
Journal: Clinical Science
Clin Sci (Lond) (1987) 72 (5): 599–604.
https://doi.org/10.1042/cs0720599
Published: 01 May 1987
... of renomedullary vasodepressor mechanisms acting directly or indirectly on the resistance vessels. 10 11 1986 3 12 1986 © 1970 The Biochemical Society and the Medical Research Society 1970 2-bromoethylamine hydrobromide cardiac output hypertension kidney renal medullary damage...
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Articles

A modified single breath method for estimation of cardiac output in humans at rest and during exercise

Y. M. H. Al-Shamma, R. Hainsworth, N. P. Silverton
Journal: Clinical Science
Clin Sci (Lond) (1987) 72 (4): 437–441.
https://doi.org/10.1042/cs0720437
Published: 01 April 1987
...Y. M. H. Al-Shamma; R. Hainsworth; N. P. Silverton 1. This study was undertaken to determine the accuracy of a modification of a single breath method for estimation of cardiac output. The technique incorporated a single rebreathing stage followed by a prolonged expiration. Cardiac output...
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Articles

Assessment of beat to beat changes in cardiac output during the Valsalva manoeuvre using electrical bioimpedance cardiography

Stephen A. Smith, Mahmood M. Salih, William A. Littler
Journal: Clinical Science
Clin Sci (Lond) (1987) 72 (4): 423–428.
https://doi.org/10.1042/cs0720423
Published: 01 April 1987
...Stephen A. Smith; Mahmood M. Salih; William A. Littler 1. Beat to beat changes in cardiac output during standardized Valsalva's manoeuvres were recorded using electrical bioimpedance cardiography in 13 normal subjects. 2. Cardiac output increased by 12 ± 5% after 1 s of straining solely because...
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Articles

Systemic and regional haemodynamic effects of a synthetic atrial natriuretic peptide in conscious rats

Carlos Caramelo, Arturo Fernandez-Cruz, Luis M. Villamediana, Elias Sanz, Diego Rodriguez-Puyol, Luis Hernando, Jose M. López-Novoa
Journal: Clinical Science
Clin Sci (Lond) (1986) 71 (3): 323–325.
https://doi.org/10.1042/cs0710323
Published: 01 September 1986
... studied in conscious rats by the radioactive microsphere technique. 2. ANP induced a 540% increase in sodium excretion and a 310% increase in urine flow. Mean arterial pressure decreased by 21 mmHg and the peripheral resistances decreased by 26%, without significant changes in cardiac output. 3. Renal...
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Articles

Validation of a Doppler technique for beat-to-beat measurement of cardiac output

Nawzer Mehta, Vincent I. Iyawe, Andrew R. C. Cummin, Susan Bayley, Kenneth B. Saunders, E. David Bennett
Journal: Clinical Science
Clin Sci (Lond) (1985) 69 (4): 377–382.
https://doi.org/10.1042/cs0690377
Published: 01 October 1985
... cardiac output (Q). 2. We tested the technique in 21 patients (53 comparisons) with various cardiovascular problems against a thermodilution method, and in four normal subjects at rest and two levels of exercise (50 and 100 W) against a nitrous oxide rebreathing method. 3. We obtained excellent overall...
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Articles

Cardiac Output, Oxygen Consumption and Renal Blood Flow in Essential Hypertension

G. M. London, M. E. Safar, J. L. Bouthier, R. M. Gitelman
Journal: Clinical Science
Clin Sci (Lond) (1984) 67 (3): 313–319.
https://doi.org/10.1042/cs0670313
Published: 01 September 1984
...G. M. London; M. E. Safar; J. L. Bouthier; R. M. Gitelman 1. Cardiac output, oxygen consumption, total blood volume and mean circulatory transit time were investigated at rest in men with sustained essential hypertension in comparison with normal subjects of the same age and sex. 2. In normal...
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Articles

The Relationship between Oxygen Delivery and Consumption in the Conscious Rat before and after Expansion of Body Fluid Volumes

J. M. Ledingham, S. Gofford, S. J. W. Evans
Journal: Clinical Science
Clin Sci (Lond) (1984) 66 (1): 91–98.
https://doi.org/10.1042/cs0660091
Published: 01 January 1984
...J. M. Ledingham; S. Gofford; S. J. W. Evans 1. Oxygen consumption and delivery (defined as the product of cardiac output, haemoglobin concentration and arterial oxygen saturation) and haemodynamic variables were examined in the conscious resting rat throughout the day and after the expansion...
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Articles

General and Regional Haemodynamic Effects of Intravenous Ergotamine in Man

P. Tfelt-Hansen, I.-L. Kanstrup, N. J. Christensen, K. Winkler
Journal: Clinical Science
Clin Sci (Lond) (1983) 65 (6): 599–604.
https://doi.org/10.1042/cs0650599
Published: 01 December 1983
...P. Tfelt-Hansen; I.-L. Kanstrup; N. J. Christensen; K. Winkler 1. The effect of intravenous ergotamine on general (blood pressure and cardiac output) and regional (splanchnic, renal and muscular) haemodynamics was studied immediately and 3 h after administration in seven male volunteers. Also...
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Articles

Influence of Age on Pulmonary Haemodynamics at Rest and during Supine Exercise

Rolf E. Ehrsam, André Perruchoud, Martin Oberholzer, Felix Burkart, Heinrich Herzog
Journal: Clinical Science
Clin Sci (Lond) (1983) 65 (6): 653–660.
https://doi.org/10.1042/cs0650653
Published: 01 December 1983
... were healthy or had indispositions which did not impair cardiac or pulmonary function. 2. Age accounted for less than 10% of total variation in resting values of right atrial, pulmonary artery and wedge pressures, and of cardiac output. 3. The pulmonary artery-wedge pressure gradient and flow...
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Articles

Haemodynamic Responses to Static and Dynamic Handgrip before and after Autonomic Blockade

Steven F. Lewis, W. Fred Taylor, Bruce C. Bastian, Robert M. Graham, William A. Pettinger, C. Gunnar Blomqvist
Journal: Clinical Science
Clin Sci (Lond) (1983) 64 (6): 593–599.
https://doi.org/10.1042/cs0640593
Published: 01 June 1983
... differences between the pressor responses for the two modes of contraction. Cardiac output increased significantly only during dynamic exercise. Total peripheral resistance increased by 2.3 ± 1.0 units for static handgrip ( P < 0.05) and by 0.7 ± 0.8 unit ( P > 0.05) for dynamic handgrip. Autonomic...
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