...), a major public health problem worldwide. However, the molecular bases of HCH have not been completely elucidated. Neuron-derived orphan receptor-1 (NOR-1) is a nuclear receptor whose role in cardiac remodelling is poorly understood. The aim of the present study was to generate a transgenic mouse over...

...Qing-Qing Wu; Yang Xiao; Yuan Yuan; Zhen-Guo Ma; Hai-Han Liao; Chen Liu; Jin-Xiu Zhu; Zheng Yang; Wei Deng; Qi-zhu Tang Cardiac remodelling is classified as physiological (in response to growth, exercise and pregnancy) or pathological (in response to inflammation, ischaemia, ischaemia/reperfusion...

... increase engraftment signals, enhance the delivery of delayed BMCs and subsequently attenuate post-infarction cardiac remodelling. A myocardial ischaemia/reperfusion (I/R) model was induced in Wistar rats via left coronary ligation for 45 min followed by reperfusion. Western blotting revealed...

... on the surface of T-lymphocytes. The role of OX40 in non-immune systems, particularly the cardiovascular system, has not been defined. In the present study, we observed a noticeable increase in OX40 expression during cardiac remodelling in rodent heart. In the present study, cardiac hypertrophy was induced...

... an association of miR-122 down-regulation with myocardial fibrosis in AS patients, probably through TGF-β 1 up-regulation and stimulation of the enzymatic systems involved in extracellular collagen type I synthesis and deposition. cardiac remodelling miR-122 myocardial fibrosis pressure overload...

... =0.04). In conclusion, the results show that a promoter haplotype containing the −3148G variant increases GDF15 transcription activity and is associated with favourable left ventricular remodelling in human essential hypertension. blood pressure cardiac remodelling growth-differentiation factor 15...