...Michael P. Hutchens; Carmen De Miguel Although the numbers of patients affected by cardiorenal syndrome keeps increasing, we lack a complete understanding of the molecular pathways involved in its development and progression. Nitric oxide synthase (NOS) may play a role in cardiorenal syndrome...

... The Author(s). Published by Portland Press Limited on behalf of the Biochemical Society 2020 cardiorenal syndrome chronic kidney disease heart failure nitric oxide Patients with heart failure (HF) frequently develop secondary kidney impairment leading to a vicious cycle injurious to both...