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Keywords: cardiotoxicity
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Clin Sci (Lond) (2024) 138 (6): 413–434.
Published: 20 March 2024
...Yiming Bo; Xin Zhao; Liliang Li Drug-induced cardiotoxicity has become one of the most common and detrimental health concerns, which causes significant loss to public health and drug resources. Cannabinoid receptors (CBRs) have recently achieved great attention for their vital roles...
Clin Sci (Lond) (2021) 135 (10): 1311–1332.
Published: 28 May 2021
..., attenuates doxorubicin‐induced NOX activation and ROS production, and was found to be a potent inhibitor of doxorubicin‐induced cytotoxicity in mice [ 48 ]. anthracycline cardiomyopathy cardiotoxicity reactive oxygen species topoisomerases Anthracyclines are highly effective...
Includes: Supplementary data
Clin Sci (Lond) (2020) 134 (19): 2595–2622.
Published: 14 October 2020
... clinical implications of treating patients with these drugs, such as increased arrhythmia burden, biventricular cardiac dysfunction, and impaired recovery from cardiotoxicity. Recommendations for future directions for preclinical and clinical work are made, highlighting the possible role of PI3Kα...
Clin Sci (Lond) (2020) 134 (13): 1859–1885.
Published: 17 July 2020
...Keith Dadson; Oscar Calvillo-Argüelles; Paaladinesh Thavendiranathan; Filio Billia Despite the known risk of cardiotoxicity, anthracyclines are widely prescribed chemotherapeutic agents. They are broadly characterized as being a robust effector of cellular apoptosis in rapidly proliferating cells...