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Keywords: cell cycle arrest
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Articles
GDF11 impairs liver regeneration in mice after partial hepatectomy
Available to Purchase
Journal:
Clinical Science
Clin Sci (Lond) (2019) 133 (20): 2069–2084.
Published: 22 October 2019
...-associated viruses-GDF11 and recombinant GDF11 protein severely impaired liver regeneration, whereas inhibition of GDF11 activity with neutralizing antibodies significantly improved liver regeneration after PH. In vitro , GDF11 treatment significantly delayed cell proliferation and induced cell-cycle arrest...
Includes: Supplementary data