... that knockdown of IGFBP7 in endothelial cells significantly decreases the expression of endothelial cell proliferation-related genes and cell number in the recovery phase but not in the acute phase of ALI. Mechanistically, using bulk-RNA sequencing and CO-IP, we found that IGFBP7 promotes phosphorylation of FOS...

.... The optical density was measured at 490 nm by a microplate reader (Thermo Scientific, U.S.A.). In cultured organoids, the proliferation of ISCs was evaluated by EdU + cell count using an EdU Cell Proliferation Assay kit (Ruibo Biotech, Guangzhou, China). Seventy-two hours after G-1 (100 nM...

... deficiency induced a mitochondria-dependent cell apoptosis, and inhibited cell proliferation via phosphorylating extracellular signal-regulated kinase 1/2 (ERK1/2) activation. Additionally, suppression of ERK1/2 with U0126 incubation could significantly reverse NELL2 deficiency triggered cell apoptosis...

... that GALNT2 was closely related to glioma cell proliferation, cycle transition, migration and invasion. Western blot analysis and lectin pull-down assays indicated that GALNT2 knockdown decreased the level of phosphorylated epidermal growth factor receptor (EGFR) and the expression of the Tn antigen on EGFR...

... Biochemical Society 2008 apoptosis cell proliferation cell cycle energy metabolism magnesium transport mitochondria Mg (magnesium; referring to both bound and free forms) is referred to as the intracellular divalent cation par excellence . Its biological role is extremely versatile...

.... Correspondence : Dr M. Losa. © 1988 The Biochemical Society and the Medical Research Society 1988 cell proliferation growth fraction pituitary neoplasm pituitary surgery 129Clinical Science (1998) 95, 129 135 (Printed in Great Britain) + R E V I E W Usefulness of markers of cell proliferation...

... alkaline phosphatase butyrate cell proliferation colonic epithelium urokinase Clinical Science (1998) 94, 671676 (Printed in Great Britain) 67 I Effect of topical butyrate on rectal epithelial kinetics and mucosal enzyme activities Peter R. GIBSON, Diana KILIAS, Ourania ROSELLA, Jenny M. DAY...

... (second messen- gers) which are involved in controlling the nuclear and cytoplasmic responses underlying the processes of cell proliferation and differentiation. The cyclic nucleotide, cyclic AMP (CAMP), was the first intracellular second messenger to be identi- fied. The prototypical system regulating...

... is suggested by the reduced colonic mucosal cell proliferation seen in response to 1,25-dihydroxyvitamin D3. Thus 1,25-dihydroxyvitamin D 3 might be expected to reduce cell proliferation in the small-bowel epithelium. 2. We have used an organ-culture system combined with the metaphase arrest technique to study...

... 1996 © 1996 The Biochemical Society and the Medical Research Society 1996 cell proliferation epidermal growth factor gastrointestinal tract intravenous (parenteral) nutrition urogastrone Clinical Science (1996) 91, 503-507 (Printed in Great Britain) Comparison of the mitogenic...

.... 15 5 1995 25 5 1995 © 1995 The Biochemical Society and the Medical Research Society 1995 cell proliferation urogastrone Clinical Science (1995) 89, I17420 (Printed in Great Britain) Rapid Communication I I7 Luminal epidermal growth factor is trophic to the small intestine...

... on mesangial cell proliferation, three daily pulses of 10 −6 mol/l H 2 O 2 resulted in a significant increase in [ 3 H]thymidine incorporation of 31 (52.6, 10.3)% (median and 75th-25th interquartile range) ( P <0.001). Both interleukin-6 and platelet-derived growth factor were also mitogenic to mesangial...

..., including polyamines [lo]. EGF-R is a transmembrane glycoprotein with intrinsic tyrosine kinase activity [21]. The truncated receptor has seauence homologv with the product of the c-erbB2 Key words: Barrett s mucosa, cell proliferation, epidermal growth factor, epidermal growth factor receptor, trans...

...R. A. Goodlad; H. Gregory; N. A. Wright 1. Intestinal epithelial cell proliferation was measured in rats maintained on total parenteral nutriton (TPN), in TPN rats given 300 μg of recombinant human epidermal growth factor (urogastrone-epidermal growth factor, URO-EGF) day −1 kg −1 , and in further...

...H. Yang; W. Morton; R. M. K. W. Lee; A. Kajetanowicz; J. B. Forrest 1. The rate of smooth muscle cell proliferation in age-matched 1-4-week-old spontaneously hypertensive (SHR) and normotensive Wistar-Kyoto (WKY) rats was compared using autoradiography. 2. Labelling index, defined as labelled cells...

... between the effects of URO-EGF and resection. Thus loss of intestinal mass had no influence on the susceptibility of the intestine to the effects of URO-EGF. Although URO-EGF significantly increased intestinal epithelial cell proliferation, it could not entirely compensate for the lack of luminal contents...

..., namely the bone-specific vitamin-K-dependent protein osteocalcin, and the enzyme alkaline phosphatase. Although stanozolol tended to increase the values, this was not seen in all experiments. 4. We conclude that human bone cells respond to stanozolol. The effects of this agent on cell proliferation may...