.... The central nervous system (CNS) in general, and the hypothalamus in particular, are intricately involved in the development and maintenance of hypertension. Over the last several decades, the understanding of the brain's role in the development of hypertension has dramatically increased. This brief review...

... changes in levels of circulating ovarian hormones [ 5 , 6 ], obesity [ 7 – 10 ], salt intake [ 11 – 13 ], stress [ 14 , 15 ] and the immune system [ 16 ]. One mechanism that is common to all these hypertensive risk factors is an increase in sympathetic nerve activity (SNA). The central nervous system...

... type 1 receptor angiotensin II type 2 receptor blood pressure central nervous system Compound 21 hypertension • Collectively, the data from our study support a role for AT 2 Rs as an important element in the beneficial arm of the RAS. We provide the first evidence that chronic selective...

... elicits the production of cytokines, enzymes and other inflammatory mediators that can have an impact on several aspects of CNS (central nervous system) homoeostasis and pathology. For example, TLR signalling plays a crucial role in initiating host defence responses during CNS microbial infection...

...Marilia G.A.G. Pereira; Christiane Becari; José A.C. Oliveira; Maria Cristina O. Salgado; Norberto Garcia-Cairasco; Claudio M. Costa-Neto The RAS (renin–angiotensin system) is classically involved in BP (blood pressure) regulation and water–electrolyte balance, and in the central nervous system...

... critical periods of growth and development may permanently alter tissue structure and function, producing effects which may persist throughout life. central nervous system fetal programming glucocorticoid type 2 isoform of 11β-hydroxysteroid dehydrogenase (11 β-HSD2) hyperglycaemia...

... 12 2 2007 artery blood pressure central nervous system dopamine receptor hypertension kidney sodium homoeostasis Essential hypertension affects 25% of the adult population and constitutes a major risk factor for stroke, myocardial infarction, heart failure and kidney failure...

... sclerosis, ischaemic and traumatic brain injury, and Alzheimer's disease, and (ii) to provide an overview of the production and action of pro-inflammatory cytokines by (peri)vascular cells in these pathologies of the CNS (central nervous system). The brain (peri)vascular compartments are highly relevant...

... homoeostasis of the entire organism. The recent discovery of a specific Epo/Epo-receptor system in the central nervous system (CNS) and cerebrospinal fluid, independently of the haematopoietic system, has further paved the way for new studies aimed at investigating the different sites of cerebral expression...

... tissue depots. However, clinical investigation of the neuronal circuitry involved in the central nervous system's processing of such satiety signals remains largely unexplored. Using percutaneously placed catheters in either the right or left internal jugular veins, we were able to quantify the release...

..., the central kinin system may participate, by both pre- and post-synaptic mechanisms, in the maintenance of hypertension in spontaneously hypertensive rats. 4 10 1991 9 12 1991 © 1992 The Biochemical Society and the Medical Research Society 1992 bradykinin central nervous system...

... not show a significant correlation. 3. We conclude that the ratio of these metabolites in the cerebrospinal fluid may reflect the ratio in the central nervous system and we suggest that this may also be true in human tissues. This finding will permit the determination of the probable methylation ratio...

...Nidia Basso; Diana Grispon; Patricia Ruiz; Alberto C. Taquini 1. The distribution of angiotensinogen and endogenous renin-like activity were analysed in different areas of the central nervous system in normal and DOC-salt-treated hypertensive rats. 2. Angiotensinogen concentration and renin-like...

... ( P < 0.05), and DAMME reduced the slope from 2.7 ± 1.7 to 1.2 ± 0.5 ( P < 0.05). 6. We conclude that endogenous opioids modulate baroreflex function in man. © 1982 The Biochemical Society and the Medical Research Society 1982 central nervous system DAMME naloxone opiates Clinical...

... balance, might be involved in the maintenance of DOCA-sodium hypertension in the rat. © 1980 The Biochemical Society and the Medical Research Society 1980 catecholamine turnover central nervous system experimental hypertension sodium depletion sympathetic nervous system Clinical Science...

... catecholamines may participate both early in the development and later in the maintenance of renovascular hypertension. © 1978 The Biochemical Society and the Medical Research Society 1978 central nervous system experimental hypertension noradrenaline phenylethanolamine- N -methyl transferase...

...J. Conway; D. T. Greenwood; D. N. Middlemiss © 1978 The Biochemical Society and the Medical Research Society 1978 β-adrenoreceptors central nervous system EDITORIAL REVIEW Central nervous actions of /7-adrenoreceptor antagonists J. CONWAY, D. T. GREENWOOD AND D. N. MIDDLEMISS...

...John L. Reid; Peter J. Lewis; Colin T. Dollery 1. The role of the central nervous system (CNS) in maintaining arterial pressure was investigated in two types of experimental hypertension in rabbits. 2. In rabbits with neurogenic hypertension produced by baroreceptor denervation, anaesthesia...