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Keywords: chemotaxis
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Articles
Clin Sci (Lond) (2015) 129 (8): 757–767.
Published: 29 July 2015
... system. Mechanistic studies revealed that both the SP receptor neurokinin-1 receptor (NK1R) and the superoxide-producing enzyme NADPH oxidase (NOX2) were necessary for SP-mediated chemotaxis in microglia. Furthermore, genetic ablation and pharmacological inhibition of NK1R or NOX2 attenuated SP-induced...
Articles
Clin Sci (Lond) (2015) 128 (4): 257–267.
Published: 17 October 2014
... the abnormal chemotaxis of CXC chemokine ligand 12 (CXCL12) in several mouse models of NASH and the relevance in the context of human non-alcoholic fatty liver disease (NAFLD). We assessed chemotactic responsiveness of CD4 + T-cells to CXCL12, the effect of AMD3100, a CXC chemokine receptor 4 (CXCR4...
Includes: Supplementary data
Articles
Clin Sci (Lond) (2009) 117 (9): 331–338.
Published: 01 September 2009
... disease, and at sites of anaerobic infection. In the present study, the effect of the SCFAs acetate, propionate and butyrate on neutrophil chemotaxis and migration was investigated. Experiments were carried out in rats and in vitro . The following parameters were measured: rolling, adherence, expression...
Articles
Clin Sci (Lond) (2002) 102 (3): 287–295.
Published: 11 February 2002
... respiratory burst in polymorphonuclear neutrophils (PMNs), but the underlying mechanisms remain unclear. OKG is usually recognized as generating glutamine, arginine and polyamines. The aim of the present study was first to determine the effects of OKG on PMN bactericidal functions (chemotaxis and respiratory...
Articles
Clin Sci (Lond) (1997) 93 (4): 355–362.
Published: 01 October 1997
... for α-SM actin expression. pFn-induced fibroblast chemotaxis can selectively recruit myofibroblasts with increased α-SM actin expression, a feature which may contribute to the altered population of cells at sites of fibrosis. 21 4 1997 20 6 1997 © 1997 The Biochemical Society and the...
Articles
Clin Sci (Lond) (1989) 77 (2): 195–203.
Published: 01 August 1989
... they did not modulate FMLP-stimulated PMN-endothelial cell adhesion. 19 12 1988 17 1 1989 © 1989 The Biochemical Society and the Medical Research Society 1989 chemotaxis N -formyl-l-methionyl-l-leucyl-l-phenylalanine leukotriene B 4 lipoxin A 4 lipoxin B 4 neutrophil...
Articles
Clin Sci (Lond) (1988) 74 (6): 645–650.
Published: 01 June 1988
... recruitment to the lung by chemotaxis. 2. Circulating PMN from patients with bronchiectasis show a variable chemotactic response to the synthetic peptide N -formyl- l -methionyl- l -leucyl- l -phenylalanine. This is similar to the response of PMN from healthy controls and suggests that failure to clear...
Articles
Clin Sci (Lond) (1988) 74 (5): 467–475.
Published: 01 May 1988
... connectivities and chemical shift assignments. The effects of LTB 3 on complement receptor enhancement, chemotaxis and lysozyme release in human neutrophils (PMN) were compared with those of LTB 4 and LTB 5 . 2. LTB 3 and LTB 4 elicited a virtually identical dose- and time-dependent enhancement in complement...
Articles
Clin Sci (Lond) (1986) 70 (1): 59–62.
Published: 01 January 1986
...B. McLaughlin; K. O'Malley; T. G. Cotter 1. In the present study we have demonstrated that human peripheral blood granulocytes from elderly subjects exhibit reduced chemotaxis and degranulation in response to stimulation with fMet-Leu-Phe. 2. Cyclic AMP levels in non-stimulated cells were not...