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Keywords: chemotherapy
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Cardiovascular-Oncology
Clin Sci (Lond) (2020) 134 (21): 2897–2927.
Published: 13 November 2020
... of cancer treatments. Therefore, numerous preclinical studies demonstrate that inhibition of CYP1B1 protects against chemotherapy-induced cardiotoxicity and prevents chemo- and radio-resistance. Most of these studies have utilized phytochemicals to inhibit CYP1B1. Since phytochemicals have multiple targets...
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Cardiovascular-Oncology
Clin Sci (Lond) (2020) 134 (19): 2595–2622.
Published: 14 October 2020
... inhibition in the progression of cancer-related cachexia and female sex and pre-existing comorbidities as independent risk factors for cardiac abnormalities after cancer treatment. cardiac arrhythmia cardio-oncology cardiotoxicity chemotherapy heart failure PI3Kα The phosphoinositide 3...
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Clin Sci (Lond) (2020) 134 (2): 155–167.
Published: 23 January 2020
... 2020 apoptosis Bim chemotherapy colorectal cancer SPZ1 To identify the molecular mechanism by which SPZ1 inhibits apoptosis, we investigated the downstream effectors of SPZ1 and apoptosis-associated proteins. ERK1/2 serves as an intracellular regulator of tumorigenic capacity...
Includes: Supplementary data
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Clin Sci (Lond) (2017) 131 (2): 113–121.
Published: 14 December 2016
... of the Biochemical Society 2016 cardio-oncology chemotherapy heart failure Heart disease and cancer are the top two causes of mortality globally, accounting for 46.1% of deaths worldwide [ 1 ]. The incidence is projected to increase by 2030. Despite effective treatments for both aetiologies...
Articles
Clin Sci (Lond) (2002) 102 (4): 417–424.
Published: 12 March 2002
...Robert C. RINTOUL; Tariq SETHI Tumour recurrence following chemotherapy remains a major obstacle to the cure of many cancers. This is exemplified by small-cell lung cancer (SCLC). Host-tumour interactions are central to tumour survival and proliferation. We hypothesized that a factor(s) within...
Articles
Clin Sci (Lond) (1997) 92 (4): 385–389.
Published: 01 April 1997
...D. M. K. Keefe; A. G. Cummins; B. M. Dale; D. Kotasek; T. A. Robb; R. E. Sage 1. Mucositis is a common side-effect of chemotherapy which is difficult to assess except by invasive means such as upper gastrointestinal endoscopy. Differential absorption of mono- and di-saccharides, such as rhamnose...
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Articles
Clin Sci (Lond) (1984) 66 (2): 147–154.
Published: 01 February 1984
... leukaemia and one patient with chronic myeloid leukaemia before and after chemotherapy. 2. Gas chromatography-mass spectrometry was used to determine plasma [ 15 N]glycine enrichment. Pool sizes and turnover rate constants were estimated from time-decay curves for isotope enrichment. 3. Turnover rate...
Articles
Clin Sci Mol Med (1975) 49 (2): 99–106.
Published: 01 August 1975
... of these compounds, which were released in association with liposomal lipid, in draining lymph nodes. 27 11 1974 © 1975 The Biochemical Society and the Medical Research Society 1975 chemotherapy drug therapy liposomes Clinical Science and Molecular Medicine (1975) 49 99-106. Liposomes...