Skip Nav Destination
Close Modal
Update search
Filter
- Title
- Author
- Author Affiliations
- Full Text
- Abstract
- Keyword
- DOI
- ISSN
- EISSN
- Issue
- Volume
- References
Filter
- Title
- Author
- Author Affiliations
- Full Text
- Abstract
- Keyword
- DOI
- ISSN
- EISSN
- Issue
- Volume
- References
Filter
- Title
- Author
- Author Affiliations
- Full Text
- Abstract
- Keyword
- DOI
- ISSN
- EISSN
- Issue
- Volume
- References
Filter
- Title
- Author
- Author Affiliations
- Full Text
- Abstract
- Keyword
- DOI
- ISSN
- EISSN
- Issue
- Volume
- References
Filter
- Title
- Author
- Author Affiliations
- Full Text
- Abstract
- Keyword
- DOI
- ISSN
- EISSN
- Issue
- Volume
- References
Filter
- Title
- Author
- Author Affiliations
- Full Text
- Abstract
- Keyword
- DOI
- ISSN
- EISSN
- Issue
- Volume
- References
NARROW
Format
Subjects
Article Type
Date
Availability
1-10 of 10
Keywords: chemotherapy
Close
Follow your search
Access your saved searches in your account
Would you like to receive an alert when new items match your search?
Sort by
Articles
Promoting mitochondrial fusion in doxorubicin-induced cardiotoxicity: a novel therapeutic target for cardioprotection
Available to PurchaseChayodom Maneechote, Thawatchai Khuanjing, Benjamin Ongnok, Apiwan Arinno, Nanthip Prathumsap, Titikorn Chunchai, Busarin Arunsak, Wichwara Nawara, Siriporn C. Chattipakorn, Nipon Chattipakorn
Journal:
Clinical Science
Clin Sci (Lond) (2022) 136 (11): 841–860.
Published: 01 June 2022
... the heart from DOX-induced myocardial damage. Modulation of mitochondrial dynamics could be a novel therapeutic target in alleviating DOX-induced cytotoxic effects without compromising its anticancer efficacy. Cancer Cardiotoxicity Chemotherapy Doxorubicin Mitochondria Mitochondrial dynamics...
Articles
In Collection
Cardiovascular-Oncology
Journal:
Clinical Science
Clin Sci (Lond) (2020) 134 (21): 2897–2927.
Published: 13 November 2020
... of cancer treatments. Therefore, numerous preclinical studies demonstrate that inhibition of CYP1B1 protects against chemotherapy-induced cardiotoxicity and prevents chemo- and radio-resistance. Most of these studies have utilized phytochemicals to inhibit CYP1B1. Since phytochemicals have multiple targets...
Articles
Cardiovascular toxicity of PI3Kα inhibitors
Available to PurchaseIn Collection
Cardiovascular-Oncology
Journal:
Clinical Science
Clin Sci (Lond) (2020) 134 (19): 2595–2622.
Published: 14 October 2020
... inhibition in the progression of cancer-related cachexia and female sex and pre-existing comorbidities as independent risk factors for cardiac abnormalities after cancer treatment. cardiac arrhythmia cardio-oncology cardiotoxicity chemotherapy heart failure PI3Kα The phosphoinositide 3...
Articles
SPZ1 promotes deregulation of Bim to boost apoptosis resistance in colorectal cancer
Available to PurchaseXiao-Yu Liu, Chang-Bo Zheng, Teng Wang, Jian Xu, Meng Zhang, Ling-Shan Gou, Linfang Jin, Xiaowei Qi, Xianhai Zeng, Hongwen Li, Shuqi Qiu, Peng Zhang
Journal:
Clinical Science
Clin Sci (Lond) (2020) 134 (2): 155–167.
Published: 23 January 2020
... 2020 apoptosis Bim chemotherapy colorectal cancer SPZ1 To identify the molecular mechanism by which SPZ1 inhibits apoptosis, we investigated the downstream effectors of SPZ1 and apoptosis-associated proteins. ERK1/2 serves as an intracellular regulator of tumorigenic capacity...
Includes: Supplementary data
Articles
An emerging epidemic: cancer and heart failure
Available to Purchase
Journal:
Clinical Science
Clin Sci (Lond) (2017) 131 (2): 113–121.
Published: 14 December 2016
... of the Biochemical Society 2016 cardio-oncology chemotherapy heart failure Heart disease and cancer are the top two causes of mortality globally, accounting for 46.1% of deaths worldwide [ 1 ]. The incidence is projected to increase by 2030. Despite effective treatments for both aetiologies...
Articles
Extracellular matrix regulation of drug resistance in small-cell lung cancer
Available to Purchase
Journal:
Clinical Science
Clin Sci (Lond) (2002) 102 (4): 417–424.
Published: 12 March 2002
...Robert C. RINTOUL; Tariq SETHI Tumour recurrence following chemotherapy remains a major obstacle to the cure of many cancers. This is exemplified by small-cell lung cancer (SCLC). Host-tumour interactions are central to tumour survival and proliferation. We hypothesized that a factor(s) within...
Articles
Effect of High-Dose Chemotherapy on Intestinal Permeability in Humans
Available to Purchase
Journal:
Clinical Science
Clin Sci (Lond) (1997) 92 (4): 385–389.
Published: 01 April 1997
...D. M. K. Keefe; A. G. Cummins; B. M. Dale; D. Kotasek; T. A. Robb; R. E. Sage 1. Mucositis is a common side-effect of chemotherapy which is difficult to assess except by invasive means such as upper gastrointestinal endoscopy. Differential absorption of mono- and di-saccharides, such as rhamnose...
Articles
Steven W. Graves, J. Paul Eder, Susan M. Schryber, Kiran Sharma, Anne Brena, Karen H. Antman, William P. Peters
Journal:
Clinical Science
Clin Sci (Lond) (1989) 77 (5): 501–507.
Published: 01 November 1989
... pressure in hypertensive individuals, and the results suggest that DLIF may contribute to the increased blood pressure in some of these subjects. 26 4 1989 3 5 1989 © 1989 The Biochemical Society and the Medical Research Society 1989 chemotherapy fluid retention hypertension (Na...
Articles
Glycine Pools and Turnover Rates in Leukaemia Patients Measured with [ 15 N]Glycine
Available to Purchase
Journal:
Clinical Science
Clin Sci (Lond) (1984) 66 (2): 147–154.
Published: 01 February 1984
... leukaemia and one patient with chronic myeloid leukaemia before and after chemotherapy. 2. Gas chromatography-mass spectrometry was used to determine plasma [ 15 N]glycine enrichment. Pool sizes and turnover rate constants were estimated from time-decay curves for isotope enrichment. 3. Turnover rate...
Articles
Liposomes as Vehicles for the Local Release of Drugs
Available to Purchase
Journal:
Clinical Science
Clin Sci Mol Med (1975) 49 (2): 99–106.
Published: 01 August 1975
... of these compounds, which were released in association with liposomal lipid, in draining lymph nodes. 27 11 1974 © 1975 The Biochemical Society and the Medical Research Society 1975 chemotherapy drug therapy liposomes Clinical Science and Molecular Medicine (1975) 49 99-106. Liposomes...