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Keywords: cholesterol 7α-mono-oxygenaseClose
Journal: Clinical Science
Clin Sci (Lond) (1981) 61 (5): 615–619.
Published: 01 November 1981
... activities of 3-hydroxy-3-methyl-glutaryl-coenzyme A (CoA) reductase and cholesterol 7α-mono-oxygenase, as well as the rate of hepatic sterol synthesis, were unchanged during the first 2 weeks of probucol. More prolonged probucol led to inhibition of the activity of these enzymes and reduction in sterol...