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Keywords: chronic inflammation
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Clin Sci (Lond) (2016) 130 (14): 1257–1268.
Published: 13 June 2016
... demonstrated that the TCF-4 transgene in macrophages aggravated high-fat diet (HFD)-induced insulin resistance and chronic inflammation, characterized by the elevation of proinflammatory cytokines in the blood, liver and white adipose tissue, as well as a proinflammatory profile of immune cells in visceral...
Includes: Supplementary data
Clin Sci (Lond) (2015) 129 (9): 797–808.
Published: 07 August 2015
... inflammation during the progression of experimental NASH (non-alcoholic steatohepatitis). chronic inflammation CX 3 CR1 dendritic cells liver fibrosis macrophages non-alcoholic fatty liver disease • In healthy livers, DCs (dendritic cells) represent a small fraction of non-parenchymal...
Includes: Supplementary data
Clin Sci (Lond) (2015) 128 (8): 493–506.
Published: 23 January 2015
... with a FOXO1 inhibitor, an antioxidant that inhibits FOXO1 or IL-1 receptor antagonist alleviates chronic inflammation and insulin resistance in high-fat diet (HFD)-fed mice. Collectively, our data suggest that obesity-associated factors such as NEFA and lipopolysaccharide (LPS) probably adopt this...
Includes: Supplementary data
Clin Sci (Lond) (2015) 128 (8): 483–491.
Published: 23 December 2014
... blockade angiotensin II receptor blocker atherosclerosis chronic inflammation cytokine • Our previous reports have demonstrated that activation of the TLR4 signal is involved in the downstream release of inflammatory cytokines in circulating monocytes obtained from patients with CAD...
Clin Sci (Lond) (2014) 126 (3): 233–241.
Published: 09 October 2013
...Mamoru Satoh; Tsuyoshi Tabuchi; Tomonori Itoh; Motoyuki Nakamura The NLRP-3 (nucleotide-binding domain, leucine-rich-containing family, pyrin domain-containing-3) inflammasome has recently emerged as a pivotal regulator of chronic inflammation. The aim of the present study was to determine whether...