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Keywords: chronic obstructive pulmonary disease
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Clin Sci (Lond) (2023) 137 (11): 895–912.
Published: 14 June 2023
... findings from these two approaches in the context of four common respiratory diseases (asthma, chronic obstructive pulmonary disease, pulmonary fibrosis, and respiratory infection). Potential methods used to identify and measure human circadian oscillations are also discussed as these will be useful...
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Clin Sci (Lond) (2023) 137 (3): 219–237.
Published: 02 February 2023
...Lynne Faherty; Sarah Kenny; Suzanne M. Cloonan Chronic obstructive pulmonary disease (COPD) is a debilitating lung disease characterised by airflow limitation, chronic bronchitis, emphysema and airway remodelling. Cigarette smoke is considered the primary risk factor for the development of COPD...
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Clin Sci (Lond) (2021) 135 (17): 2067–2083.
Published: 01 September 2021
...Sudhir Kotnala; Yerin Kim; Charu Rajput; Hymavathi Reddyvari; Sudhir Bolla; Nathaniel T. Marchetti; Beata Kosmider; Karim Bahmed; Umadevi S. Sajjan Dipeptidyl peptidase 4 (DPP4) expression is increased in the lungs of chronic obstructive pulmonary disease (COPD). DPP4 is known to be associated...
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Clin Sci (Lond) (2019) 133 (4): 551–564.
Published: 18 February 2019
...Xuhua Yu; Huei Jiunn Seow; Hao Wang; Desiree Anthony; Steven Bozinovski; Lin Lin; Ji-Ming Ye; Ross Vlahos Chronic Obstructive Pulmonary Disease (COPD) is a major incurable global health burden and will become the third largest cause of death in the world by 2030. It is well established...
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Clin Sci (Lond) (2018) 132 (3): 375–379.
Published: 08 February 2018
... in a chronic lung disease condition. We would like to take this further and discuss new insights in this area. chronic obstructive pulmonary disease drug therapy fibrosis infection inflammation Currently in clinical practice, the mainstay of COPD treatment is inhaled corticosteroids (ICS) which...
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Clin Sci (Lond) (2016) 130 (10): 839–841.
Published: 19 April 2016
...Aran Singanayagam; Sebastian L. Johnston Inhaled β 2 -adrenoceptor agonists are a mainstay of therapy for airways diseases and are almost universally prescribed for patients with asthma or chronic obstructive pulmonary disease (COPD). Very few studies have evaluated the efficacy of these commonly...
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Clin Sci (Lond) (2015) 129 (3): 245–258.
Published: 08 May 2015
...Aran Singanayagam; Nicholas Glanville; Ross P. Walton; Julia Aniscenko; Rebecca M. Pearson; James W. Pinkerton; Jay C. Horvat; Philip M. Hansbro; Nathan W. Bartlett; Sebastian L. Johnston Viral exacerbations of chronic obstructive pulmonary disease (COPD), commonly caused by rhinovirus (RV...
Includes: Supplementary data
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Clin Sci (Lond) (2013) 125 (10): 483–493.
Published: 16 July 2013
...Cedric Hubeau; John E. Kubera; Katherine Masek-Hammerman; Cara M. M. Williams Increased systemic and pulmonary levels of IL-6 (interleukin-6) are associated with the severity of exacerbations and decline of lung function in patients with COPD (chronic obstructive pulmonary disease). Whether IL-6...
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Clin Sci (Lond) (2009) 117 (8): 281–291.
Published: 24 August 2009
...William D.-C. Man; Paul Kemp; John Moxham; Michael I. Polkey Skeletal muscle dysfunction in COPD (chronic obstructive pulmonary disease) patients, particularly of the quadriceps, is of clinical interest because it not only influences the symptoms that limit exercise, but may also contribute...
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Clin Sci (Lond) (2009) 117 (7): 251–264.
Published: 17 August 2009
...William D.-C. Man; Paul Kemp; John Moxham; Michael I. Polkey COPD (chronic obstructive pulmonary disease), although primarily a disease of the lungs, exhibits secondary systemic manifestations. The skeletal muscles are of particular interest because their function (or dysfunction) not only...
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Clin Sci (Lond) (2000) 98 (1): 91–101.
Published: 29 November 1999
... was carried out by 13 healthy subjects and 21 patients with chronic obstructive pulmonary disease (COPD) to evaluate the difference in A I as respiratory drive between the two groups in the absence of a respiratory circuit. In patients with COPD, A I responses to minute ventilation, mean inspiratory flow...
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Clin Sci (Lond) (1997) 92 (1): 59–62.
Published: 01 January 1997
... with essential hypertension, 12 with heart failure, 10 with ascites due to cirrhosis, 12 with chronic renal failure, four with hypoxia due to chronic obstructive pulmonary disease and 12 control subjects. 3. Plasma levels (mean ± SEM) in patients with essential hypertension (16.3 ± 1.9 pmol/l), congestive heart...
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