... consisted mainly of metformin (19/29) and sulfonylureas (4/28). Some subjects were treated with a statin (12/29) or with aspirin (7/29). In a translational approach, we have previously been able to demonstrate that NO production is reduced and oxidant stress increased in the renal circulation of human...

... is complicated by the multiple vascular beds involved (hepatic, splanchnic, peripheral, renal and pulmonary), the differences in the underlying cause of portal hypertension (hepatic versus pre-hepatic) and the slow evolution of the hyperdynamic state. The autonomic nervous system, circulating vasodilators...

... of HPV, suggesting that reinnervation of the pul- monary vascular bed did not account for persistent HPV and that HPV persists in the human trans- planted lung despite the loss of autonomic neural innervation. Key words: circulation, human heart-lung trans- plantation, hypoxia, pulmonary vasoconstriction...

...R. Jelnes; K. H. Tønnesen 1. Twenty-four hour continuous recording of xenon ( 133 Xe) wash-out from the forefoot was performed on patients with normal circulations ( n = 10) and on patients with different degrees of arterial insufficiency ( n = 36). 2. During day hours the calculated subcutaneous...

... remained low during the 30 min recorded. 20 6 1983 4 7 1983 © 1983 The Biochemical Society and the Medical Research Society 1983 catalase circulation kidney oxygen free radicals superoxide dismutase warm ischaemia Clinical Science (1983) 65, 605-610 605 Effects of free...

...K. Wasserman © 1981 The Biochemical Society and the Medical Research Society 1981 anaerobic threshold circulation exercise ventilation exertional dyspnoea lactic acidosis oxygen uptake Clinical Science (1981) 61,7-13 7 EDITORIAL RE VIEW Physiology of gas exchange and exertional...

...K. K. F. Ng; S. Duffy; W. J. Louis; A. E. Doyle 1. The blood-bathed organ technique was employed to study the effects of angiotensin II and catecholamines on an isolated everted rat aorta bathed in the extracorporeal circulating blood of adult dogs and cats. 2. When the injections were made...

... 1975 circulation neural regulation positive feedback Clinical Science and Molecular Medicine (1975) 48,259s-260s. Spinal sympathetic reflexes in the cat and the pathogenesis of arterial hypertension A. M A L L I A N I , F. L O M B A R D I , M. P A G A N I , G. R E C O R D A T I A N D P. J . S...

... on exercise responses of differences in body muscle can be allowed for by multiplying this index by lean body mass (LBM). The lower the (size-adjusted) physiological strain index, the fitter the individual subject. Key words : exercise, ventilation, circulation, normal data. The maximum oxygen uptake (Vo has...