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Keywords: clinical trialsClose
Clin Sci (Lond) (2018) 132 (15): 1699–1709.
Published: 16 August 2018
...@glasgow.ac.uk ) 26 06 2018 02 08 2018 03 08 2018 © 2018 The Author(s). Published by Portland Press Limited on behalf of the Biochemical Society 2018 cardiovascular disease clinical trials glucagon-like peptide-1 type 2 diabetes People with Type 2 diabetes mellitus (T2D...
Iain D. Croall, Valerie Lohner, Barry Moynihan, Usman Khan, Ahamad Hassan, John T. O’Brien, Robin G. Morris, Daniel J. Tozer, Victoria C. Cambridge, Kirsty Harkness, David J. Werring, Andrew M. Blamire, Gary A. Ford, Thomas R. Barrick, Hugh S. Markus
Clin Sci (Lond) (2017) 131 (12): 1361–1373.
Published: 07 June 2017
... fractional anisotropy (FA) and mean diffusivity (MD) have been proposed as clinical trial markers of cerebral small vessel disease (SVD) due to their associations with outcomes such as cognition. However, studies investigating this have been predominantly single-centre. As clinical trials are likely to be...
Includes: Supplementary data
Othman Al-Sawaf, Tim Clarner, Athanassios Fragoulis, Yuet Wai Kan, Thomas Pufe, Konrad Streetz, Christoph Jan Wruck
Clin Sci (Lond) (2015) 129 (12): 989–999.
Published: 18 September 2015
... disease or cardiovascular diseases. The present review summarizes promising findings from basic research and shows which Nrf2-targeting therapies are currently being investigated in clinical trials and which agents have already entered clinical practice. Correspondence: Dr Othman Al-Sawaf (email...
Clin Sci (Lond) (2000) 99 (4): 255–260.
Published: 06 September 2000
... novel series of pyrazolopyrimidinones. Optimization of structure–activity relationships and pharmacokinetic properties led to sildenafil, which proved essentially devoid of cardiovascular activity in clinical trials. However, the emerging role of nitric oxide and cGMP in controlling blood flow in the...
Clin Sci (Lond) (1992) 82 (5): 469–470.
Published: 01 May 1992
...Michael E. Allen © 1992 The Biochemical Society and the Medical Research Society 1992 clinical trials European Community good clinical practice pharmaceutical industry Clinical Science (1992) 82, 469-470 (Printed in Great Britain) Editorial Review 469 Good clinical practice: uncommon...