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Keywords: coagulation
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Articles

Using serpins cysteine protease cross-specificity to possibly trap SARS-CoV-2 Mpro with reactive center loop chimera

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In Collection
Coronavirus
Mohamad Aman Jairajpuri, Shoyab Ansari
Journal: Clinical Science
Clin Sci (Lond) (2020) 134 (17): 2235–2241.
https://doi.org/10.1042/CS20200767
Published: 01 September 2020
... and management of coagulopathy in COVID-19 . J. Thromb. Haemost. 18 , 1023 – 1026 10.1111/jth.14810 37. Tang N. , Li D. , Wang X. and Sun Z. ( 2020 ) Abnormal coagulation parameters are associated with poor prognosis in patients with novel coronavirus pneumonia . J. Thromb...
View articletitled, Using serpins cysteine protease cross-specificity to possibly trap SARS-CoV-2 Mpro with reactive center loop chimera
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Articles

Substrates of Factor XIII-A: roles in thrombosis and wound healing

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Victoria R. Richardson, Paul Cordell, Kristina F. Standeven, Angela M. Carter
Journal: Clinical Science
Clin Sci (Lond) (2013) 124 (3): 123–137.
https://doi.org/10.1042/CS20120233
Published: 02 October 2012
... and in Figure 3 . The coagulation cascade is activated upon vascular damage, resulting in the sequential cleavage and activation of coagulation factors and culminating in thrombin generation and fibrin formation. FXIIIa-dependent cross-linking of fibrin results in the formation of a stable fibrin...
View articletitled, Substrates of Factor XIII-A: roles in thrombosis and wound healing
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Articles

Relationship of waist and hip circumference with coagulation and fibrinolysis in postmenopausal women

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Roger E. Peverill, Helena J. Teede, Erica Malan, Dimitra Kotsopoulos, Joseph J. Smolich, Barry P. Mcgrath
Journal: Clinical Science
Clin Sci (Lond) (2007) 113 (9): 383–391.
https://doi.org/10.1042/CS20070084
Published: 01 October 2007
...Roger E. Peverill; Helena J. Teede; Erica Malan; Dimitra Kotsopoulos; Joseph J. Smolich; Barry P. Mcgrath The contribution of obesity to the occurrence of cardiovascular events may not be wholly related to its influence on traditional risk factors. Coagulation and fibrinolysis may also influence...
View articletitled, Relationship of waist and hip circumference with coagulation and fibrinolysis in postmenopausal women
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Articles

Different contribution of interleukin-6 and cortisol activity to total plasma fibrin concentration and to acute mental stress-induced fibrin formation

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Roland von KÄNEL, Brigitte M. KUDIELKA, Dirk HANEBUTH, Daniel PRECKEL, Joachim E. FISCHER
Journal: Clinical Science
Clin Sci (Lond) (2005) 109 (1): 61–67.
https://doi.org/10.1042/CS20040359
Published: 23 June 2005
...Roland von KÄNEL; Brigitte M. KUDIELKA; Dirk HANEBUTH; Daniel PRECKEL; Joachim E. FISCHER Acute mental stress may contribute to atherosclerosis by affecting inflammation and coagulation; however, the crosstalk between inflammation and coagulation during stress has not been studied. In the present...
View articletitled, Different contribution of interleukin-6 and cortisol activity to total plasma fibrin concentration and to acute mental stress-induced fibrin formation
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Articles

Adenosine inhibits thrombin-induced expression of tissue factor on endothelial cells by a nitric oxide-mediated mechanism

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Esteban C. GABAZZA, Tatsuya HAYASHI, Masaru IDO, Yukihiko ADACHI, Koji SUZUKI
Journal: Clinical Science
Clin Sci (Lond) (2002) 102 (2): 167–175.
https://doi.org/10.1042/cs1020167
Published: 03 January 2002
... activity of NO. Correspondence: Dr Esteban Cesar Gabazza (e-mail [email protected] ) 11 5 2001 2 8 2001 21 9 2001 The Biochemical Society and the Medical Research Society © 2002 2002 adenosine receptor coagulation phosphodiesterase 167Clinical Science...
View articletitled, Adenosine inhibits thrombin-induced expression of tissue factor on endothelial cells by a nitric oxide-mediated mechanism
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Articles

Effects of combined oral hormone replacement therapy on tissue factor pathway inhibitor and factor VII

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Roger E. PEVERILL, Helena J. TEEDE, Joseph J. SMOLICH, Erica MALAN, Dimitra KOTSOPOULOS, Peter G. TIPPING, Barry P. McGRATH
Journal: Clinical Science
Clin Sci (Lond) (2001) 101 (1): 93–99.
https://doi.org/10.1042/cs1010093
Published: 13 June 2001
... inhibitor (TFPI), an inhibitor of extrinsic pathway activation, may contribute to increases in thrombin generation occurring with HRT. Healthy postmenopausal women aged 50–75 years received placebo ( n = 19) or oral combined HRT ( n = 18) and had blood collected for measurement of factor VII coagulation...
View articletitled, Effects of combined oral hormone replacement therapy on tissue factor pathway inhibitor and factor VII
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Articles

Effects of balloon mitral valvuloplasty on systemic and regional left atrial levels of prothrombin fragment 1+2 in mitral stenosis

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Foo Leong LI-SAW-HEE, Gregory Y. H. LIP
Journal: Clinical Science
Clin Sci (Lond) (2001) 100 (5): 467–468.
https://doi.org/10.1042/cs1000467
Published: 26 March 2001
...Foo Leong LI-SAW-HEE; Gregory Y. H. LIP Correspondence : Dr G. Y. H. Lip (e-mail [email protected] ). 2 11 2000 The Biochemical Society and the Medical Research Society © 2001 2001 atrium coagulation mitral stenosis 467Clinical Science (2001) 100, 467 470 (Printed...
View articletitled, Effects of balloon mitral valvuloplasty on systemic and regional left atrial levels of prothrombin fragment 1+2 in mitral stenosis
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Articles

Effects of balloon mitral valvuloplasty on systemic and regional left atrial levels of prothrombin fragment 1+2 in mitral stenosis: authors’ reply

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R. E. PEVERILL, J. J. SMOLICH
Journal: Clinical Science
Clin Sci (Lond) (2001) 100 (5): 468–470.
https://doi.org/10.1042/cs1000468
Published: 26 March 2001
...R. E. PEVERILL; J. J. SMOLICH Correspondence : Dr R. E. Peverill (e-mail [email protected] ). 23 11 2000 The Biochemical Society and the Medical Research Society © 2001 2001 atrium coagulation mitral stenosis 467Clinical Science (2001) 100, 467 470...
View articletitled, Effects of balloon mitral valvuloplasty on systemic and regional left atrial levels of prothrombin fragment 1+2 in mitral stenosis: authors’ reply
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Articles

Left atrial thrombin generation and prothrombin fragment 1+2

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A. D. BLANN, G. Y. H. LIP
Journal: Clinical Science
Clin Sci (Lond) (2000) 99 (5): 411–412.
https://doi.org/10.1042/cs0990411
Published: 26 October 2000
...A. D. BLANN; G. Y. H. LIP Correspondence : Dr G. Y. H. Lip (e-mail [email protected] ) 26 5 2000 The Biochemical Society and the Medical Research Society © 2000 2000 coagulation D-dimer F1+2 mitral stenosis thrombin generation 411Clinical Science (2000) 99, 411...
View articletitled, Left atrial thrombin generation and prothrombin fragment 1+2
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Articles

Effects of balloon mitral valvuloplasty on systemic and regional left atrial levels of prothrombin fragment 1+2 in mitral stenosis

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Roger E. PEVERILL, Richard W. HARPER, T. Eng GAN, Joseph J. SMOLICH
Journal: Clinical Science
Clin Sci (Lond) (2000) 99 (4): 269–276.
https://doi.org/10.1042/cs0990269
Published: 30 August 2000
...–venous F1+2 difference, in patients with increased left atrial thrombin generation. The divergent changes in venous and left atrial levels of F1+2 further highlight the limitations of assessing regional changes in coagulation activity by measuring venous levels of coagulation markers. Correspondence...
View articletitled, Effects of balloon mitral valvuloplasty on systemic and regional left atrial levels of prothrombin fragment 1+2 in mitral stenosis
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Articles

Increased left atrial thrombin generation in mitral stenosis is not reflected in arterial prothrombin fragment 1+2 levels

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Roger E. PEVERILL, Richard W. HARPER, T. Eng GAN, Joseph J. SMOLICH
Journal: Clinical Science
Clin Sci (Lond) (2000) 98 (4): 501–506.
https://doi.org/10.1042/cs0980501
Published: 22 March 2000
..., Monash Medical Centre, 246 Clayton Road, Clayton, Victoria 3168, Australia (e-mail [email protected] ). 4 8 1999 19 10 1999 13 1 2000 The Biochemical Society and the Medical Research Society © 2000 2000 atrium coagulation mitral stenosis 501Clinical...
View articletitled, Increased left atrial thrombin generation in mitral stenosis is not reflected in arterial prothrombin fragment 1+2 levels
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Articles

Failure of Thrombin Inhibition to Prevent Intracoronary Thrombosis in the Dog

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Philip R. Belcher, Angela J. Drake-Holland, John W. Hynd, Mark I. M. Noble
Journal: Clinical Science
Clin Sci (Lond) (1996) 90 (5): 363–368.
https://doi.org/10.1042/cs0900363
Published: 01 May 1996
... that specific thrombin inhibition, despite affecting coagulation, is relatively ineffective in preventing intracoronary thrombosis under conditions of high shear. 17 7 1995 19 12 1995 15 1 1996 © 1996 The Biochemical Society and the Medical Research Society 1996 artery blood...
View articletitled, Failure of Thrombin Inhibition to Prevent Intracoronary Thrombosis in the Dog
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Articles

Coagulation and fibrinolytic systems in type I diabetes: effects of venous occlusion and insulin-induced hypoglycaemia

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Iwona Wieczorek, Alistair C. H. Pell, Brian McIver, Ian R. MacGregor, Christopher A. Ludlam, Brian M. Frier
Journal: Clinical Science
Clin Sci (Lond) (1993) 84 (1): 79–86.
https://doi.org/10.1042/cs0840079
Published: 01 January 1993
...Iwona Wieczorek; Alistair C. H. Pell; Brian McIver; Ian R. MacGregor; Christopher A. Ludlam; Brian M. Frier 1. The effects of venous occlusion on the coagulation and fibrinolytic systems were investigated in six patients with type 1 (insulin-dependent) diabetes and 11 age- and sex-matched non...
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