...H. R. Bhatt; J. C. Linnell 1. The effects of haemorrhage on vitamin B 12 (cobalamin) homoeostasis have been studied in rats with and without prior administration of 57 Co-labelled cyanocobalamin. 2. Arteriovenous differences in radioactivity and endogenous B 12 were measured across the thigh...

.... We conclude that methionine synthetase is both present and active in the small intestinal mucosal cells of the rat. Key words: cobalamin, methionine synthetase, mucosal cells, nitrous oxide, vitamin BIZ. Abbreviation: S-CH3-H4PteGlu, Ns-methyltetra- hydrofolate. Introduction Methionine synthetase (EC...

...Julie A. Owens; J. S. D. Scott; W. G. E. Cooksley 1. The effect of cobalamin deficiency on whole body cobalamin content and its turnover was examined in the rat. Quantitative and qualitative changes in hepatic cobalamin were also followed and the effect of deficiency on the turnover...

...J. S. D. Scott; E. P. W. Bowman; W. G. E. Cooksley 1. Binding of cobalamin (Cbl) was compared in liver and kidney plasma membranes prepared from rat and human tissues. 2. Single, high-affinity, saturable (200 pmol/l), binding sites for TC II-Cbl were found in all tissues; by contrast no receptors...

...Ralph Carmel; Stephan B. Abramson; Ian G. Renner 1. To clarify further the role of the pancreas in cobalamin absorption we characterized pure human pancreatic juice. With isolated exceptions, samples of the pure juice contained little cobalamin and had low cobalamin-binding capacities. 2. Ten of 13...

... The Biochemical Society and the Medical Research Society 1977 cobalamin transcobalamin vitamin B 12 Clinical Science and Molecular Medicine (1977) 53.453451. The carriers of native vitamin B,, in normal human serum C. A. HALL Hematology Research Laboratory, Veterans Administration Hospital...