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1-22 of 22
Keywords: coeliac disease
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Articles
microRNA profiles in coeliac patients distinguish different clinical phenotypes and are modulated by gliadin peptides in primary duodenal fibroblasts
Available to PurchaseValentina Vaira, Leda Roncoroni, Donatella Barisani, Gabriella Gaudioso, Silvano Bosari, Gaetano Bulfamante, Luisa Doneda, Dario Conte, Carolina Tomba, Maria Teresa Bardella, Stefano Ferrero, Martina Locatelli, Luca Elli
Journal:
Clinical Science
Clin Sci (Lond) (2014) 126 (6): 417–423.
Published: 15 November 2013
...Valentina Vaira; Leda Roncoroni; Donatella Barisani; Gabriella Gaudioso; Silvano Bosari; Gaetano Bulfamante; Luisa Doneda; Dario Conte; Carolina Tomba; Maria Teresa Bardella; Stefano Ferrero; Martina Locatelli; Luca Elli CD (coeliac disease) is a frequent autoimmune disorder of the small bowel...
Articles
Expression of cholecystokinin in the duodenum of patients with coeliac disease: respective role of atrophy and lymphocytic infiltration
Available to PurchasePierre H. DEPREZ, Christine SEMPOUX, Christine DE SAEGER, Jacques RAHIER, Paul MAINGUET, Stanislas PAUWELS, André GEUBEL
Journal:
Clinical Science
Clin Sci (Lond) (2002) 103 (2): 171–177.
Published: 19 July 2002
... and the relationship between the distinctive types of mucosal lesions observed in coeliac disease and the number of duodenal CCK cells and their peptide and mRNA content. Duodenal biopsies were obtained in ten controls and nineteen coeliac patients [seven with atrophic mucosa, six with increased numbers...
Articles
Improvement in intestinal permeability precedes morphometric recovery of the small intestine in coeliac disease
Available to PurchaseAdrian G. CUMMINS, Fiona M. THOMPSON, Ross N. BUTLER, John C. CASSIDY, David GILLIS, Mark LORENZETTI, Emma K. SOUTHCOTT, Peter C. WILSON
Journal:
Clinical Science
Clin Sci (Lond) (2001) 100 (4): 379–386.
Published: 26 February 2001
...Adrian G. CUMMINS; Fiona M. THOMPSON; Ross N. BUTLER; John C. CASSIDY; David GILLIS; Mark LORENZETTI; Emma K. SOUTHCOTT; Peter C. WILSON It is often difficult to assess small bowel recovery in adults with coeliac disease on a gluten-free diet (GFD). This prospective study compares changes...
Articles
Simultaneous Assessment of Intestinal Permeability and Lactose Tolerance with Orally Administered Raffinose, Lactose and 1-Arabinose
Available to Purchase
Journal:
Clinical Science
Clin Sci (Lond) (1990) 79 (2): 175–183.
Published: 01 August 1990
.... The median 5 h urinary sugar excretion was 0.26% of the ingested raffinose, 0.05% of lactose and 17.5% of l-arabinose. 3. In 143 patients with gastrointestinal disease, excretion of both ingested raffinose and lactose was significantly increased in coeliac disease in relapse or in partial remission...
Articles
Comparison between the cellobiose/mannitol and 51 Cr-labelled ethylenediaminetetra-acetate absorption tests in the detection of coeliac disease
Available to PurchaseD. Martines, A. I. Morris, I. T. Gilmore, A. Williams, H. Stockdale, M. Critchley, G. A. Smith, D. Billington
Journal:
Clinical Science
Clin Sci (Lond) (1988) 75 (4): 375–378.
Published: 01 October 1988
... permeability in coeliac disease. 2. In patients with clinically proven coeliac disease, 13 out of 14 (93%) had abnormal urinary cellobiose/mannitol ratios, while only five out of 12 (42%) had abnormal urinary recoveries of 51 Cr-EDTA. Thus, the cellobiose/mannitol absorption test is more sensitive...
Articles
Changes in jejunal permeability and passive permeation of sugars in intestinal biopsies in coeliac disease and Crohn's disease
Available to Purchase
Journal:
Clinical Science
Clin Sci (Lond) (1988) 74 (4): 427–431.
Published: 01 April 1988
... with coeliac disease and 11 patients with Crohn's disease. Total mucosal permeation was corrected for surface area measured morphometrically to provide an index of mucosal permeability. 2. In untreated coeliac disease, permeation of mannitol was reduced by 35% ( P = 0.006) and that of raffinose was increased...
Articles
Gliadin binding to rat and human enterocytes
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Journal:
Clinical Science
Clin Sci (Lond) (1987) 72 (5): 593–598.
Published: 01 May 1987
... in the pathogenesis of coeliac disease. ClinicalScience( 1987) 12, 593-598 593 Gliadin binding to rat and human enterocytes J. COLYER, P. J. KUMAR, N. M. WALDRON*, M. L. CLARK AND M. J. G. FARTHING Department of Gastroenterology, St Bartholomew s Hospital, and *Department of Chemistty, Queen Mary s College...
Articles
Reappraisal of the ‘lectin hypothesis' in the aetiopathogenesis of coeliac disease
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Journal:
Clinical Science
Clin Sci (Lond) (1986) 71 (1): 105–110.
Published: 01 July 1986
... and as such cannot be regarded as true lectins. 4. Mucosal damage in coeliac disease is unlikely therefore to be related to lectin-like activity of gliadin. 31 1 1986 20 2 1986 © 1986 The Biochemical Society and the Medical Research Society 1986 cell agglutination coeliac disease gliadin...
Articles
Antigenic Reactivity of Peptides Derived from Wheat Gluten with Sera from Patients with Coeliac Disease
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Journal:
Clinical Science
Clin Sci (Lond) (1985) 69 (1): 97–104.
Published: 01 July 1985
... disease (IBD) and healthy individuals. The coeliac group had significantly higher ( P < 0.05) antibody levels to fraction B than either of the control groups [medians: coeliac disease ( n = 21), 0.247; IBD ( n = 17) 0.019; healthy controls ( n = 13) 0.020]. Five coeliac sera which gave high absorbance...
Articles
Human jejunal transglutaminase: demonstration of activity, enzyme kinetics and substrate specificity with special relation to gliadin and coeliac disease
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Journal:
Clinical Science
Clin Sci (Lond) (1985) 68 (5): 573–579.
Published: 01 May 1985
..., elastin and zein exhibited very low acceptor activities. 3. Increased transglutaminase activity was demonstrated in jejunal biopsies from four patients with untreated coeliac disease compared with 14 control subjects and eight patients with inflammatory bowel disease. Eight patients with coeliac disease...
Articles
Clinical Testing of Gliadin Fractions in Coeliac Patients
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Journal:
Clinical Science
Clin Sci (Lond) (1984) 66 (3): 357–364.
Published: 01 March 1984
...P. J. Ciclitira; D. J. Evans; N. L. K. Fagg; E. S. Lennox; R. H. Dowling 1. Since the toxic fraction of cereal flour which damages the small bowel mucosa of patients with coeliac disease has not been fully defined in vivo , we studied the effect of intraduodenal infusions of different doses...
Articles
T-Lymphocyte Subsets in Adult Coeliac Disease
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Journal:
Clinical Science
Clin Sci (Lond) (1983) 65 (1): 89–90.
Published: 01 July 1983
...G. R. Corazza; P. Tabacchi; M. Frisoni; M. Londei; D. Bastia; G. Gasbarrini 1. As a defect of suppressor function has been hypothesized in the pathogenesis of coeliac disease, we measured, by monoclonal antibodies, the inducer/suppressor T-cell ratio in adult coeliac disease. 2. No statistical...
Articles
A Radioimmunoassay for α-and β -Gliadins
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Journal:
Clinical Science
Clin Sci (Lond) (1983) 64 (6): 655–659.
Published: 01 June 1983
... of assaying for α-gliadin in prepared foods is of special value since α-, β-, γ- and ω-gliadin have been shown to exacerbate coeliac disease. 6 9 1982 10 12 1982 © 1983 The Biochemical Society and the Medical Research Society 1983 coeliac disease gluten free diet and foods...
Articles
Altered Jejunal Surface pH in Coeliac Disease: Its Effect on Propranolol and Folic Acid Absorption
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Journal:
Clinical Science
Clin Sci (Lond) (1982) 63 (4): 373–380.
Published: 01 October 1982
...G. Kitis; M. L. Lucas; H. Bishop; A. Sargent; R. E. Schneider; J. A. Blair; R. N. Allan 1. Propranolol and folic acid absorption were studied separately in healthy subjects, non-coeliac patients and patients with treated and untreated coeliac disease. 2. The surface pH of jejunal biopsy samples...
Articles
Propranolol Absorption in Untreated Coeliac Disease
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Journal:
Clinical Science
Clin Sci (Lond) (1982) 63 (1): 81–85.
Published: 01 July 1982
... is decreased in the proximal jejunum in untreated coeliac disease but overall absorption in the small bowel is not impaired. 21 10 1981 29 1 1982 © 1982 The Biochemical Society and the Medical Research Society 1982 absorption coeliac disease jejunum propranolol Clinical Science...
Articles
Simple Method of Assessing Splenic Function in Coeliac Disease
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Journal:
Clinical Science
Clin Sci (Lond) (1981) 60 (1): 109–113.
Published: 01 January 1981
...G. R. Corazza; A. W. Bullen; R. Hall; P. J. Robinson; M. S. Losowsky 1. Erythrocytes with membrane abnormalities seen on interference contrast microscopy (‘pitted erythrocytes’) were counted in venous blood samples from patients with treated coeliac disease and dermatitis herpetiformis, and from...
Articles
Analytical Subcellular Fractionation of Jejunal Biopsy Specimens: Enzyme Activities, Organelle Pathology and Response to Gluten Withdrawal in Patients with Coeliac Disease
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Journal:
Clinical Science
Clin Sci Mol Med (1978) 55 (3): 285–292.
Published: 01 September 1978
...T. J. Peters; P. E. Jones; G. Wells 1. Portions of jejunal biopsy specimens from patients with coeliac disease were homogenized in isotonic sucrose solution and subjected to analytical subcellular fractionation by sucrose-density-gradient centrifugation. 2. The activities and distribution of marker...
Articles
Effect of Hyperosmolar Stimuli and Coeliac Disease on the Permeability of the Human Gastrointestinal Tract
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Journal:
Clinical Science
Clin Sci Mol Med (1978) 54 (5): 495–501.
Published: 01 May 1978
... with coeliac disease. 5. The possible location of such pores in the gastrointestinal mucosa is discussed in relation to the cell membrane, the intercellular junction, and the sites of cell exfoliation. 28 6 1977 8 11 1977 © 1978 The Biochemical Society and the Medical Research Society 1978...
Articles
Application of Analytical Subcellular Fractionation Techniques and Tissue Enzymic Analysis to the Study of Human Pathology
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Journal:
Clinical Science
Clin Sci Mol Med (1977) 53 (6): 505–511.
Published: 01 December 1977
...T. J. Peters © 1977 The Biochemical Society and the Medical Research Society 1977 coeliac disease congestive cardiomyopathy enzyme analysis granulomatous Clinical Science and Molecular Medicine (1977) 53, 505-51 1. EDITORIAL REVIEW Application of analytical subcellular fractionation...
Articles
Coeliac Disease: The Abolition of Gliadin Toxicity by Enzymes from Aspergillus Niger
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Journal:
Clinical Science
Clin Sci Mol Med (1977) 53 (1): 35–43.
Published: 01 July 1977
... The Biochemical Society and the Medical Research Society 1977 brush-border enzymes coeliac disease gliadin intestine mucosa xylose Clinical Science and Molecular Medicine (1977) 53,3543. Coeliac disease: the abolition of gliadin toxicity by enzymes from Aspergillus niger J. J. PHELAN, FIONA M...
Articles
The Effect of pH on Folic Acid Absorption in Man
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Journal:
Clinical Science
Clin Sci Mol Med (1976) 51 (4): 363–368.
Published: 01 October 1976
...J. F. MacKenzie; R. I. Russell 1. Pteroylmonoglutamic acid (PteGlu) absorption has been measured by using the technique of small-intestinal perfusion with tritiated PteGlu in normal subjects and in patients with coeliac disease. 2. At similar intrajejunal pH, patients with untreated coeliac disease...
Articles
Enzyme Activities and Properties of Lysosomes and Brush Borders in Jejunal Biopsies from Control Subjects and Patients with Coeliac Disease
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Journal:
Clinical Science
Clin Sci Mol Med (1975) 48 (4): 259–267.
Published: 01 April 1975
...T. J. Peters; J. R. Heath; M. H. Wansbrough-Jones; W. F. Doe 1. Reduced activities of four enzymes from brush borders were found in intestinal biopsies from patients with untreated coeliac disease. The activities returned towards control values after treatment by gluten withdrawal. Parallel changes...