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Keywords: colon cancer
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Articles
Clin Sci (Lond) (2017) 131 (19): 2439–2450.
Published: 22 September 2017
... receptor potential channel 5 (TrpC5), a receptor-activated non-selective Ca 2+ channel, is correlated with tumor metastasis in colon cancer patients. Moreover, in colon cancer cells, overexpression of TrpC5 caused a robust rise in the concentration of ([Ca 2+ ] i ), decreased E-cadherin, and increased...
Includes: Supplementary data
Articles
Clin Sci (Lond) (2012) 123 (5): 295–306.
Published: 16 May 2012
... vivo cultures of human CRC explants. Similarly, 2-14 reduces COX-2, but not COX-1, in tumoural areas developing in a mouse model of CAC (colitis-associated colon cancer). Finally, we show that 2-14 exhibits in vitro and in vivo anti-mitogenic effects in DLD-1, a COX-deficient CRC cell line. Taken...
Includes: Supplementary data
Articles
Clin Sci (Lond) (2008) 115 (4): 107–127.
Published: 15 July 2008
... roles in this tissue include homoeostatic regulation of intestinal cell proliferation/differentiation and modulation of inflammation associated with inflammatory bowel disease and colon cancer. Analysis of mouse epithelial cells in the intestine and colon has clearly demonstrated that ligand activation...
Articles
Clin Sci (Lond) (1995) 88 (4): 491–499.
Published: 01 April 1995
... mmol/l, and there is some evidence that short-chain fatty acids may alter ganglioside expression in colon cancer cells. 2. Because of the importance of gangliosides in cancer pathogenesis, we investigated the effects of n-butyrate on ganglioside expression of colonic (human and murine) and non-colonic...