... of extracellular volume fraction and excess extracellular fluid, i.e. oedema. The model suggests that the proportional increase in absolute Na + content and concentration due to different degrees of oedema is higher than the parallel increase in water content, thus making Na + a more sensitive index to detect...

...D. S. Emmanouel; M. D. Lindheimer; A. I. Katz 1. The effects of unilateral nephrectomy on urinary concentration and dilution were studied in Sprague—Dawley rats. To exclude incomplete suppression of antidiuretic hormone, free water formation was also studied in rats with congenital diabetes...