...Zhiling Luo; Longjiang Xu; Jiang Lu; Yan Shen; Yongyan Tang; Xiuyun Wang; Yilin Wu; Hao Sun; Tao Guo Background/Aims: Congenital heart disease (CHD) is one of the most common and severe congenital defects. The incidence of fetal cardiac malformation is increased in the context of maternal...

...Xiaobo Gao; Panpan Zheng; Liping Yang; Haiyan Luo; Chen Zhang; Yongqiang Qiu; Guoying Huang; Wei Sheng; Xu Ma; Cailing Lu GDF1 plays an important role in left–right patterning and genetic mutations in the coding region of GDF1 are associated with congenital heart disease (CHD). However, the genetic...

... of human diseases, including cardiovascular disease. In the present review, I discuss well-established and emerging roles of miRNAs in cardiac development, their relevance to congenital heart disease and unresolved questions in the field for future investigation, as well as emerging therapeutic...

...I. Adatia; G. J. Kemp; D. J. Taylor; G. K. Radda; B. Rajagopalan; S. G. Haworth 1. Exercise tolerance is impaired in congenital heart disease. To examine the possible contribution of abnormalities in skeletal muscle bioenergetics, we used 31 P nuclear magnetic resonance spectroscopy to investigate...

...M. R. H. Taylor 1. In contrast to the diminished ventilatory response to hypoxia which has been found at rest in cyanotic congenital heart disease, hyperventilation was noted on exercise in children who were cyanosed. 2. Sixteen children had low arterial oxygen saturations on exercise and thirteen...

... haemodynamic assessment. 22 1 1973 © 1973 The Biochemical Society and the Medical Research Society 1973 oxygen consumption congenital heart disease Clinical Science and Molecular Medicine (1973) 45, 107-114. OXYGEN CONSUMPTION I N CHILDREN WITH CONGENITAL DISEASES OF THE HEART C. T...