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Keywords: coronary heart disease
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Articles
Journal:
Clinical Science
Clin Sci (Lond) (2019) 133 (2): 205–224.
Published: 22 January 2019
... 12 2018 02 01 2019 © 2019 The Author(s). Published by Portland Press Limited on behalf of the Biochemical Society 2019 coronary heart disease cardiovascular disease PCSK9 inhibitors There is now overwhelming evidence to support reducing low-density lipoprotein cholesterol...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (2017) 131 (9): 833–846.
Published: 19 April 2017
...) and macrovascular [coronary heart disease (CHD), myocardial infarction, peripheral arterial disease (PAD) and stroke] disease are different in the two sexes. In general, men appear to be at a higher risk for diabetic microvascular complications, while the consequences of macrovascular complications may be greater...
Articles
Yu Han, Xiang Liao, Zhao Gao, Sufei Yang, Caiyu Chen, Yukai Liu, Wei Eric Wang, Gengze Wu, Xiongwen Chen, Pedro A. Jose, Ye Zhang, Chunyu Zeng
Journal:
Clinical Science
Clin Sci (Lond) (2016) 130 (24): 2279–2293.
Published: 10 November 2016
... the adhesion of monocytes to vascular endothelial cells via activation of the TLR4/NF-κB pathway. Inhibition of TLR4 may be an alternative strategy to reduce cTnI-induced myocardial I/R injury. adhesion factor cardiac troponin I coronary heart disease endothelial cell myocardial ischaemia–reperfusion...
Includes: Supplementary data
Articles
Journal:
Clinical Science
Clin Sci (Lond) (2009) 116 (2): 87–98.
Published: 15 December 2008
... levels and CHD (coronary heart disease) risk. The cardioprotective effects of HDLs have been attributed to several mechanisms, including their involvement in the reverse cholesterol transport pathway. HDLs also have antioxidant, anti-inflammatory and antithrombotic properties and promote endothelial...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (2009) 116 (1): 41–43.
Published: 28 November 2008
...Adam Mullan; Naveed Sattar The oxidation hypothesis for CHD (coronary heart disease) is attractive; however, the almost universal failure of antioxidant vitamin supplementation as a CVD (cardiovascular disease) risk modifier challenges the oxidation hypothesis, at least as a concept that easily...
Articles
Mark Woodward, Kevin D. Croft, Trevor A. Mori, Henrietta Headlam, Xiao Suo Wang, Cacang Suarna, Mark J. Raftery, Stephen W. MacMahon, Roland Stocker
Journal:
Clinical Science
Clin Sci (Lond) (2009) 116 (1): 53–60.
Published: 28 November 2008
...) oxidation and the risk of fatal or non-fatal coronary heart disease in a general population. This may be due to a true lack of association or insufficient power. Cases and unique controls were compared, for continuous variables, using medians and extreme values. Associations between markers...
Articles
Marileia Scartezini, Christina Hubbart, Ros A. Whittall, Jackie A. Cooper, Andrew H. W. Neil, Steve E. Humphries
Journal:
Clinical Science
Clin Sci (Lond) (2007) 113 (11): 435–441.
Published: 01 November 2007
... with plasma lipid levels and CHD (coronary heart disease) in healthy U.K. men and patients with clinically defined definite FH (familial hypercholesterolaemia). Genotypes were determined using PCR and restriction enzyme digestion in 2444 healthy middle-aged (50–61 years) men from the prospective NPHSII...
Articles
Philippa J. Talmud, David M. Flavell, Khaled Alfakih, Jackie A. Cooper, Anthony J. Balmforth, Mohan Sivananthan, Hugh E. Montgomery, Alistair S. Hall, Steve E. Humphries
Journal:
Clinical Science
Clin Sci (Lond) (2007) 112 (12): 617–624.
Published: 14 May 2007
...Philippa J. Talmud; David M. Flavell; Khaled Alfakih; Jackie A. Cooper; Anthony J. Balmforth; Mohan Sivananthan; Hugh E. Montgomery; Alistair S. Hall; Steve E. Humphries LVH [LV (left ventricular) hypertrophy] is an independent risk factor for CHD (coronary heart disease). During LVH, the preferred...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (2006) 111 (5): 333–340.
Published: 13 October 2006
.... This prompted us to perform a case-control study to investigate the relationship of ACE2 polymorphisms with CHD (coronary heart disease) and MI (myocardial infarction). Three single nucleotide polymorphisms in the ACE2 gene (1075A/G, 8790A/G and 16854G/C) were genotyped by PCR-RFLP (restriction-fragment-length...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (2006) 110 (3): 327–328.
Published: 10 February 2006
...Gordon D. O. Lowe Prospective epidemiological studies have shown associations of circulating inflammatory markers with risk of CHD (coronary heart disease); however, these associations are modest after adjustment for confounding by established risk factors, and do not add significantly...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (2005) 109 (2): 171–176.
Published: 25 July 2005
...Hiren Divecha; Naveed Sattar; Ann Rumley; Lynne Cherry; Gordon D. O. Lowe; Roger Sturrock Men with AS (ankylosing spondylitis) are at elevated risk for CHD (coronary heart disease) but information on risk factors is sparse. We compared a range of conventional and novel risk factors in men...
Articles
Altan ONAT, Bülent UZUNLAR, Gülay HERGENÇ, Mehmet YAZICI, Ibrahim SARI, Hüseyin UYAREL, Günay CAN, Vedat SANSOY
Journal:
Clinical Science
Clin Sci (Lond) (2005) 108 (2): 129–135.
Published: 21 January 2005
...Altan ONAT; Bülent UZUNLAR; Gülay HERGENÇ; Mehmet YAZICI; Ibrahim SARI; Hüseyin UYAREL; Günay CAN; Vedat SANSOY In the present study, we examined (i) whether C3 (complement C3) was an independent marker of prevalent CHD (coronary heart disease), and (ii) which preferential associations existed...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (2003) 104 (3): 323–327.
Published: 17 February 2003
...Sybille GRUSKA; Ingo JENDRAL; Rainer RETTIG; Günter KRAATZ The present study was designed to test the hypothesis that enhanced intracellular calcium signalling and increased sodium/lithium countertransport (Na + /Li + CT) activity may be associated with coronary heart disease (CHD) in non-diabetic...
Articles
Jonathan VALABHJI, Avril J. McCOLL, Michael SCHACHTER, Surinder DHANJIL, William RICHMOND, Robert S. ELKELES
Journal:
Clinical Science
Clin Sci (Lond) (2001) 101 (6): 659–670.
Published: 22 November 2001
...Jonathan VALABHJI; Avril J. McCOLL; Michael SCHACHTER; Surinder DHANJIL; William RICHMOND; Robert S. ELKELES Type I diabetes is associated with a high incidence of coronary heart disease (CHD), despite a normal or even increased concentration of high-density lipoprotein (HDL) cholesterol...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (2000) 99 (3): 247–251.
Published: 23 August 2000
... have found the D allele to be associated with MI, coronary heart disease (CHD) or other cardiac pathology, while others have not. In the present study 713 consecutive patients, < 50 years of age, documented prospectively with angiographic CHD (> 50% diameter stenosis of at least one coronary...
Articles
B. A. GRIFFIN, A. M. MINIHANE, N. FURLONGER, C. CHAPMAN, M. MURPHY, D. WILLIAMS, J. J. WRIGHT, C. M. WILLIAMS
Journal:
Clinical Science
Clin Sci (Lond) (1999) 97 (3): 269–276.
Published: 15 July 1999
... for coronary heart disease in the free-living population. While much of the atherogenicity of small, dense LDL is known to arise from its structural properties, the extent to which an increase in the number of small, dense LDL particles (hyper-apoprotein B) contributes to this risk of coronary heart disease...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (1998) 95 (2): 115–128.
Published: 01 August 1998
...D. J. P. BARKER 1. Many human fetuses have to adapt to a limited supply of nutrients. In doing so they permanently change their structure and metabolism. 2. These ‘programmed' changes may be the origins of a number of diseases in later life, including coronary heart disease and the related...
Articles
Iftikhar Ul Haq, Lawrence E. Ramsay, David M. Pickin, Wilfred W. Yeo, Peter R. Jackson, John N. Payne
Journal:
Clinical Science
Clin Sci (Lond) (1996) 91 (4): 399–413.
Published: 01 October 1996
... >5.5mmol/l who have coronary heart disease, other forms of atherosclerotic vascular disease, or who are free of vascular disease but have a risk of major coronary events ≥ 1.5% per year. Choice of an appropriate treatment policy will require (i) knowledge of the proportion of the population who will need...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (1996) 90 (4): 243–253.
Published: 01 April 1996
...Keith N. Frayn; Christine M. Williams; Peter Arner © 1996 The Biochemical Society and the Medical Research Society 1996 coronary heart disease insulin resistance non-esterified fatty acids non-insulin-dependent diabetes obesity stress Clinical Science (1996) W, 243-253 (Printed...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (1995) 89 (4): 333–342.
Published: 01 October 1995
...Dilys J. Freeman; Chris J. Packard © 1995 The Biochemical Society and the Medical Research Society 1995 coronary heart disease lipoprotein metabolism smoking triacylgycerol Clinical Science (1995) 89, 333--342 (Printed in Great Britain) Editorial Review Smoking and plasma lipoprotein...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (1992) 82 (1): 1–8.
Published: 01 January 1992
...Keith N. Frayn; Simon W. Coppack © 1992 The Biochemical Society and the Medical Research Society 1992 adipose tissue coronary heart disease insulin insulin resistance lipoproteins non-esterified fatty acids triacylglycerol Clinical Science (1992) 82, 1-8 (Printed in Great Britain...
Articles
Journal:
Clinical Science
Clin Sci Mol Med (1978) 55 (s4): 325s–328s.
Published: 01 December 1978
... risk for coronary heart disease which could offset partly the beneficial effects of a lowered blood pressure in diuretic-treated patients with hypertension. © 1978 The Biochemical Society and the Medical Research Society 1978 coronary heart disease diuretics lipids α-lipoproteins β...
Articles
Journal:
Clinical Science
Clin Sci Mol Med (1976) 51 (s3): 661s–663s.
Published: 01 December 1976
... and Molecular Medicine (1 976) 51, 661~663s. Alcohol use, hypertension and coronary heart disease J . D. MATHEWS Unirersity of Melbourne, Department of Medicine, Royal Melbourne Hospital, Victoria. Australia Summary 1 . Male death rates from hypertension and stroke in England and Wales in 1949-53 were highest...
Articles
Journal:
Clinical Science
Clin Sci Mol Med (1976) 51 (5): 475–482.
Published: 01 November 1976
... coronary heart disease exercise test high-density lipoprotein low-density lipoprotein Clinical Science and Molecular Medicine (1976) 51,475482. Inverse relationship in Jamaica between plasma high-density lipoprotein cholest er ol concentration and coronary- dis ease risk as predicted by multiple risk...
Articles
Journal:
Clinical Science
Clin Sci Mol Med (1973) 45 (s1): 107s–110s.
Published: 01 August 1973
... only after 45 years of age. 3. In contrast to this, weight gain influences both pressures positively regardless of age. © 1994 The Biochemical Society and the Medical Research Society 1994 blood pressure age body weight coronary heart disease distribution curves male steelmill Clinical...
