... levels of the cardiospecific protein troponin-T (Tn-T) during cardiopulmonary bypass. ADM (pg/ml) and Tn-T (ng/ml) were measured in coronary sinus blood before and after aortic cross-clamp and in venous blood 6 ;h after surgery in 22 coronary-bypass patients. Based on the pre- and post-clamp Tn-T levels...

... dogs from 87 ± 11 to a maximum of 1263 ± 592 pmol/l at 30 min ( P < 0.01), falling to 411 ± 42 pmol/l after 60 min and to 146 ± 70 pmol/l after 240 min of rapid continuous pacing ( P < 0.01 compared with 30 min). Coronary sinus ANP concentrations showed a similar pattern, rising from 241 ± 79...

... min at 250 beats/min. 2. Pacing increased mean right atrial and mean pulmonary wedge pressure ( P < 0.05), and decreased cardiac output and mean arterial pressure ( P < 0.05). 3. Coronary sinus atrial natriuretic peptide (ANP) concentrations were approximately fourfold greater than arterial...