... of pharmacological inhibition of 11β-HSD on collecting duct Na + reabsorption in vivo . Adrenalectomized rats ( n = 14) were infused intravenously with high-dose corticosterone, and late-distal tubules were perfused orthogradely with artificial tubular fluid containing [ 14 C]inulin and 22 Na; urinary recoveries...

..., weighing 350-500g (normal rats). Panhypopituitarism was produced surgically through the transauricular route [9] in rats aged 2- 4 months, weighing 250-35Og. A week after the procedure, blood samples were obtained for screen- ing of pituitary functions by measurement of thyrox- ine and corticosterone...

... respiratory distress syndrome corticosterone histamine lung injury tryptase © 1994 The Biochemical Society and the Medical Research Society 1994 21 12 1992 11 8 1993 ...

...C. J. Kenyon; N. A. Saccoccio; D. J. Morris 1. The mineralocorticoid activity of corticosterone based on acute changes in urinary Na + /K + ratios in adrenalectomized rats was 1000 times less than that of aldosterone. However, corticosterone had only kaliuretic actions whereas aldosterone had both...

... with controls. 6. The possibility that a reduction in extracellular fluid volume (due to a natriuresis) and/or a peripheral vasodilatation contributed to the antihypertensive effect of KCl loading is discussed. adrenal gland aldosterone corticosterone hypertension plasma volume potassium chloride ©...

...B. C. Williams; J. G. McDougall; J. F. Tait; S. A. S. Tait 1. The efflux of 45 Ca from prelabelled dispersed rat adrenal capsular and decapsulated cell preparations was studied with a column superfusion system. Corticosterone and aldosterone outputs were measured by direct and extraction...

... the metabolism of aldosterone or cortisol. 4. Spironolactone administration produced: (a) a marked increase in both aldosterone secretion and plasma renin activity, but no change in the plasma aldosterone/plasma renin activity ratio, the cortisol secretion rate or the plasma corticosterone concentration; (b...

... elevations of plasma aldosterone and 18-hydroxycorticosterone concentrations that return to near-control values, and (c) brisk initial increases in plasma 18-hydroxydeoxycorticosterone and corticosterone concentrations that fall to 20–68% of peak values 30 h thereafter. 2. Dexamethasone (8 mg/day, orally...

... with zona glomerulosa K + content. 20 12 1976 26 5 1977 © 1977 The Biochemical Society and the Medical Research Society 1977 adrenal cortex aldosterone corticosterone electron microprobe potassium sodium Clinical Science and Molecular Medicine (1977) 53, 423-430. Detection...

... have been investigated. Corticosterone secretion was also measured. Previously reported results showing a significant increase in potassium content with high external potassium were confirmed. However, angiotensin II slightly, but significantly, decreased potassium content. No significant change...

...F. A. Mendelsohn; C. Mackie 1. Intracellular K + content, water spaces and corticosterone output were measured in isolated zona glomerulosa and zona fasciculata-reticularis cell suspensions of rat adrenal cortex, after incubations in vitro under conditions designed to alter steroidogenesis. 2...