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Mónica B. Jiménez-Castro, Elsa Negrete-Sánchez, Araní Casillas-Ramírez, Jose Gulfo, Ana I. Álvarez-Mercado, María Eugenia Cornide-Petronio, Jordi Gracia-Sancho, Juan Rodés, Carmen Peralta
Clin Sci (Lond) (2017) 131 (8): 733–746.
Published: 06 April 2017
...Mónica B. Jiménez-Castro; Elsa Negrete-Sánchez; Araní Casillas-Ramírez; Jose Gulfo; Ana I. Álvarez-Mercado; María Eugenia Cornide-Petronio; Jordi Gracia-Sancho; Juan Rodés; Carmen Peralta In the present study, we examined the effects of cortisol on steatotic and non-steatotic liver grafts from...
Includes: Supplementary data
Clin Sci (Lond) (2012) 122 (7): 349–359.
Published: 07 December 2011
... =23) using Q-PCR (quantitative PCR), and correlated these data to days of pregnancy and maternal stress, as well as placental and fetal weight. Maternal and fetal cortisol levels were also measured. JEG-3 and BeWo cells, used as placental in vitro models, were treated with cortisol and DEPTOR...
Beth A. Beidleman, Stephen R. Muza, Charles S. Fulco, Allen Cymerman, Janet E. Staab, Michael N. Sawka, Steven F. Lewis, Gary S. Skrinar
Clin Sci (Lond) (2006) 111 (2): 163–169.
Published: 13 July 2006
... and during both exercise work bouts for measurements of WBC count, leucocyte subset counts, cortisol, adrenaline (epinephrine) and noradrenaline (norepinephrine). WBC, neutrophil and lymphocyte counts increased significantly ( P <0.05) during rest and exercise from SL to PreIAE and decreased ( P...
Mark E. Davis, Christopher J. Pemberton, Timothy G. Yandle, John G. Lainchbury, Miriam T. Rademaker, M. Gary Nicholls, Christopher M. Frampton, A. Mark Richards
Clin Sci (Lond) (2005) 109 (4): 381–388.
Published: 23 September 2005
... output in association with attenuation of vasopressor hormone systems and enhancement of renal function. In a previous study, we demonstrated in the first human studies that infusion of Ucn1 elevates corticotropin (‘ACTH’), cortisol and ANP (atrial natriuretic peptide), and suppresses the hunger-inducing...
Clin Sci (Lond) (2005) 109 (1): 61–67.
Published: 23 June 2005
... study, we investigated the association of plasma fibrinogen, plasma IL-6 (interleukin-6) and free salivary cortisol with the procoagulant marker D-dimer reflecting fibrin formation both over a 2-h period and in response to acute mental stress. Twenty-one male volunteers (mean age, 47±8 years) underwent...
Clin Sci (Lond) (2004) 107 (1): 47–53.
Published: 23 June 2004
...Ulla FRISK; Joel OLSSON; Per NYLÉN; Robert G. HAHN Biochemical markers for the circadian rhythm were studied in patients treated at the ICU (intensive care unit) of two regional hospitals. A normal rhythm is characterized by a relatively higher melatonin and a lower cortisol excretion at night...
Roland von KÄNEL, Brigitte M. KUDIELKA, Adham ABD-el-RAZIK, Marie-Louise GANDER, Karl FREY, Joachim E. FISCHER
Clin Sci (Lond) (2004) 107 (1): 89–95.
Published: 23 June 2004
... tested for an association of overnight urinary catecholamine and cortisol excretion with morning plasma levels of fibrinogen, PAI-1 (plasminogen activator inhibitor-1) and D-dimer. Participants (639 male industrial employees) with a complete dataset were studied (age, 41±11 years; mean±S.D.). Subjects...
Stan H.M. VAN UUM, Brian R. WALKER, Ad R.M.M. HERMUS, C.G.J. (Fred) SWEEP, Paul SMITS, Peter W. DE LEEUW, Jacques W.M. LENDERS
Clin Sci (Lond) (2002) 102 (2): 203–211.
Published: 11 January 2002
...Stan H.M. VAN UUM; Brian R. WALKER; Ad R.M.M. HERMUS; C.G.J. (Fred) SWEEP; Paul SMITS; Peter W. DE LEEUW; Jacques W.M. LENDERS The 11β-hydroxysteroid dehydrogenase (11β-HSD) isoenzymes catalyse the interconversion of cortisol and cortisone. Type 1 11β-HSD mainly converts cortisone into active...
Clin Sci (Lond) (2001) 101 (6): 739–747.
Published: 20 November 2001
...Samina KHANI; John A. TAYEK Android obesity is associated with increased cortisol secretion. Direct effects of cortisol on gluconeogenesis and other parameters of insulin resistance were determined in normal subjects. Gluconeogenesis was determined using the reciprocal pool model of Haymond and...
Richard W. TROUGHTON, Christopher M. FRAMPTON, Lynley K. LEWIS, Timothy G. YANDLE, A. Mark RICHARDS, M. Gary NICHOLLS
Clin Sci (Lond) (2001) 101 (1): 103–109.
Published: 14 June 2001
.... During ACTH infusion, AM increased heart rate ( P < 0.01), plasma adrenaline ( P < 0.01) and plasma noradrenaline ( P < 0.05), and augmented the cortisol response ( P < 0.01), but was without effect on aldosterone levels and blood pressure. We conclude that the threshold for the effects of AM...
Clin Sci (Lond) (2000) 98 (1): 71–79.
Published: 23 November 1999
...G. M. HALL; D. PEERBHOY; A. SHENKIN; C. J. R. PARKER; P. SALMON Changes in circulating levels of catecholamines, cortisol, glucose, interleukin-6 and C-reactive protein and in the leucocyte count were investigated for 7 days after surgery in 158 patients undergoing hip or knee arthroplasty. We...
Clin Sci (Lond) (1999) 96 (6): 589–595.
Published: 07 May 1999
...-thrombotic therapy in 148 patients with myocardial infarction (MI); 76 patients with unstable angina (UA) pectoris were also studied, together with 27 patients with non-cardiac chest pain (NCP). There were significant progressive increases in the concentrations of catecholamines, cortisol, glucose and...
Clin Sci (Lond) (1998) 95 (4): 513–517.
Published: 01 October 1998
...Andrew M. WILSON; Erika J. SIMS; Allan D. STRUTHERS; Brian J. LIPWORTH 1. As mineralocorticoid and adrenocorticoid activity are both under the diurnal control of adrenocorticotropic hormone secretion, we aimed to evaluate whether the normal circadian rhythm of cortisol and aldosterone secretion was...
Clin Sci (Lond) (1990) 78 (1): 49–54.
Published: 01 January 1990
...P. M. Stewart; A. M. Wallace; S. M. Atherden; C. H. Shearing; C. R. W. Edwards 1. 11β-Hydroxysteroid dehydrogenase is an enzyme complex consisting of 11β-dehydrogenase and 11-oxoreductase responsible for the interconversion of cortisol to cortisone in man. Inhibition of 11β-dehydrogenase (e.g...
Jan Wernerman, Danielle Botta, Folke Hammarqvist, Stig Thunell, Alexandra von der Decken, Erik Vinnars
Clin Sci (Lond) (1989) 77 (6): 611–616.
Published: 01 December 1989
... skeletal muscle was investigated. Healthy volunteers were given a 6 h infusion of adrenaline ( n = 8), Cortisol ( n = 8), a triple-hormone combination of adrenaline, Cortisol and glucagon ( n = 8), or saline ( n = 8) 2. The total ribosome concentration declined by 30.4 ± 7.2% in the triple-hormone group...
Clin Sci (Lond) (1989) 77 (3): 323–327.
Published: 01 September 1989
... and mouth occlusion pressure responses to hypercapnia in 12 healthy male subjects. In addition, we examined the effect of repetitive hypercapnia on plasma β-endorphin and Cortisol levels. 3. A weak but significant negative relationship between the ventilatory response to hypercapnia and basal plasma β...
Clin Sci (Lond) (1989) 76 (6): 625–630.
Published: 01 June 1989
... naloxone. We have therefore investigated the actions of saline placebo and increasing bolus doses of intravenous naloxone (25, 100 and 250 μg/kg) on the plasma noradrenaline, adrenaline, adrenocorticotrophin (ACTH) and cortisol responses to a cold-pressor test in six males and two females in a double-blind...
Clin Sci (Lond) (1987) 73 (5): 489–495.
Published: 01 November 1987
...A. M. Richards; G. Tonolo; R. Fraser; J. J. Morton; B. J. Leckie; S. G. Ball; J. I. S. Robertson 1. Diurnal changes in plasma concentrations of atrial natriuretic peptide (ANP), renin, angiotensin II, aldosterone, Cortisol and antidiuretic hormone were investigated in seven normal volunteers...
Clin Sci (Lond) (1987) 73 (4): 411–416.
Published: 01 October 1987
... control drink there was no evidence from measurements of circulating adrenaline, noradrenaline, Cortisol, aldosterone or renin of activation of the sympathoadrenal axis, adrenal cortex or renin–angiotensin systems after alcohol. 31 3 1987 21 4 1987 © 1970 The Biochemical Society and the...
Clin Sci (Lond) (1987) 72 (6): 725–735.
Published: 01 June 1987
... women with essential or renovascular hypertension. Plasma albumin, Cortisol and oestriol were measured concurrently. 2. Plasma CBG increased two and a half to three times during pregnancy. In those women who developed hypertension in pregnancy (mean arterial pressure > 107 mmHg), the plasma CBG...
Clin Sci (Lond) (1985) 69 (1): 37–40.
Published: 01 July 1985
...Anna C. Athow; Anna T. Sewerniak; Tina P. Barton; C. G. Clark; M. R. Lewin 1. The blood cortisol and gastric acid responses to insulin hypoglycaemia were investigated in 18 healthy control subjects and 14 patients with endoscopically proven duodenal ulceration. 2. In both controls and patients...
Clin Sci (Lond) (1982) 63 (4): 397–400.
Published: 01 October 1982
... are all synthesized from a common precursor (pro-opiocortin), and plasma Cortisol in 10 normal subjects. 2. Experimental pain was produced by inflation to 250 mmHg of a sphygmomanometer cuff, placed above the elbow of the ‘dominant’ arm, after which the subject squeezed a hand dynamometer, loaded to...
Clin Sci (Lond) (1982) 62 (2): 137–141.
Published: 01 February 1982
... blood pressure or heart rate during exposure to noise. 3. Adrenaline, noradrenaline, prolactin, cortisol and growth hormone concentrations in venous plasma were not affected during noise stimulation. 11 5 1981 9 9 1981 © 1982 The Biochemical Society and the Medical Research Society...
Clin Sci (Lond) (1981) 61 (s7): 265s–268s.
Published: 01 December 1981
...S. A. Atlas; D. B. Case; Jean E. Sealey; J. H. Laragh 1. Plasma cortisol at 08.00 hours was significantly higher ( P < 0.005) in patients with high-renin essential or renovascular hypertension (22.6 ± 1.6 μg/100 ml) than in patients with normal-renin (15.4 ± 1.2) or low-renin (11.9 ± 1.2) forms...
Clin Sci (Lond) (1980) 59 (s6): 311s–313s.
Published: 01 December 1980
... some patients. © 1980 The Biochemical Society and the Medical Research Society 1980 arterial hypertension autonomic insufficiency cortisol noradrenaline sympathetic nervous system tricyclic antidepressant Clinical Science ( 1980) 59,3 1 1 s-3 13s 311s Determination of noradrenaline...
Clin Sci (Lond) (1980) 59 (1): 19–27.
Published: 01 July 1980
...H. B. Stoner; K. N. Frayn; R. A. Little; C. J. Threlfall; D. W. Yates; R. N. Barton; D. F. Heath 1. Plasma concentrations of glucose, lactate, amino acids, non-esterified fatty acids, glycerol, ketone bodies, insulin and cortisol were measured in 43 elderly patients with hypothermia. In 15 of these...
Clin Sci (Lond) (1980) 58 (3): 227–233.
Published: 01 March 1980
... alter the metabolism of aldosterone or cortisol. 4. Spironolactone administration produced: (a) a marked increase in both aldosterone secretion and plasma renin activity, but no change in the plasma aldosterone/plasma renin activity ratio, the cortisol secretion rate or the plasma corticosterone...
Clin Sci (Lond) (1979) 57 (s5): 307s–311s.
Published: 01 December 1979
...E. G. Biglieri; B. Chang; J. Hirai; N. Brust; C. R. Rost; M. Schambelan 1. Adrenocorticotropin (ACTH)-induced steroidogenesis, obtained by continuous administration of ACTH for 3 days, produces in man (a) sustained elevations of plasma deoxycorticosterone and cortisol concentrations, (b) transient...
Clin Sci (Lond) (1979) 56 (6): 563–573.
Published: 01 June 1979
...H. B. Stoner; K. N. Frayn; R. N. Barton; C. J. Threlfall; R. A. Little 1. The plasma concentrations of glucose, lactate, amino acids, non-esterified fatty acids, glycerol, ketone bodies, ethanol, cortisol and insulin were measured in patients within a few hours of injury and before treatment. The...
Clin Sci Mol Med (1977) 53 (4): 401–404.
Published: 01 October 1977
.... The two subjects who developed an increase in plasma arginine vasopressin concentration had a significant rise in serum cortisol. 3. Breathing 100% nitrogen until impairment of consciousness caused no rise in plasma arginine vasopressin concentration. 6 7 1977 23 2 1977 © 1977 The...
Clin Sci Mol Med (1977) 53 (3): 233–239.
Published: 01 September 1977
...K. Kondo; M. S. Manku; D. F. Horrobin; R. Boucher; J. Genest 1. In the perfused rat mesenteric vascular bed, the effects of angiotensin II, cortisol and prostaglandin E 2 on the vascular responses to noradrenaline or potassium chloride were studied. 2. Angiotensin II in subpressor concentrations...
Clin Sci Mol Med (1977) 52 (4): 333–336.
Published: 01 April 1977
...K. G. M. M. Alberti; D. G. Johnston © 1977 The Biochemical Society and the Medical Research Society 1977 catabolism Cortisol glucorticoids hormones Clinical Science and Molecular Medicine, 52, 333-336. EDITORIAL REVIEW Cortisol and catabolism: a new perspective K. G. M. M. ALBERT1 A...
Clin Sci Mol Med (1975) 49 (3): 201–206.
Published: 01 September 1975
...J. D. Few; F. J. Imms; J. S. Weiner 1. Changes in plasma concentrations of catecholamines and Cortisol were measured before and after static exercise performed by the subject pushing with both legs against a strain-gauge bar. No marked changes in plasma catecholamine were observed but plasma...
Clin Sci Mol Med (1974) 46 (3): 403–407.
Published: 01 March 1974
...D. O. Cosgrove; J. S. Jenkins 1. Plasma cortisols were measured in nine patients undergoing pelvic surgery under epidural anaesthesia. 2. Compared with response under general anaesthesia, the cortisol response was usually delayed and diminished, sometimes to an extreme degree. 3. No clinical...
Clin Sci Mol Med (1973) 45 (5): 633–654.
Published: 01 November 1973
... hormone and Cortisol were shown to be directly related to the degree of hypoglycaemia induced. 14 3 1973 © 1973 The Biochemical Society and the Medical Research Society 1973 human insulin porcine proinsulin metabolism growth hormone Cortisol plasma glucose Clinical Science and...
Clin Sci Mol Med (1973) 45 (4): 533–541.
Published: 01 October 1973
...P. Jaffe; P. König; O. Ijaduola; S. Walker; S. Godfrey 1. The changes in peak expiratory flow rate (PEF) and plasma cortisol were studied in relation to a 6 min period of treadmill running in six normal and eighteen asthmatic subjects. Of the asthmatics patients, five were not receiving treatment...
Clin Sci (1972) 43 (3): 343–354.
Published: 01 September 1972
... leucocyte pyrogen. This failure could be a problem of quantity of plasma used or of an endotoxin-refractory state. 5. The bearing of these observations on the mechanism of JHR and the uselessness of cortisol in modifying the reaction are discussed. 18 2 1972 © 1972 The Biochemical Society and...
Clin Sci (1972) 43 (2): 289–298.
Published: 01 August 1972
...Margaret E. Hankin; Helen M. Theile; A. W. Steinbeck 1. The 24 h urinary excretion of free cortisol and aldosterone-18-glucuronide has been studied in twenty-three control and twenty-three grossly obese subjects by a double-isotope-dilution derivative method. 2. Day-night variation of plasma and...