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1-27 of 27
Keywords: cyclic AMP
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Articles
Journal:
Clinical Science
Clin Sci (Lond) (1996) 91 (5): 527–537.
Published: 01 November 1996
..., and phosphorylation by protein kinases. The large number of receptors, G-proteins and adenylate cyclases provides a complex signalling network that integrates and interprets a multitude of convergent inputs. adenylate cyclase cyclic AMP G-proteins signal transduction Clinical Science (1996) 91, 527-537...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (1996) 91 (1): 3–16.
Published: 01 July 1996
...A. Mark Richards; M. Gary Nicholls; Lynley Lewis; John G. Lainchbury © 1996 The Biochemical Society and the Medical Research Society 1996 cyclic AMP heart failure hypertension natriuresis G-protein-linked receptors vasodilator peptides Clinical Science (1996) 91, 3-16 (Printed...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (1995) 89 (4): 421–429.
Published: 01 October 1995
... catecholamines cyclic AMP hormone-sensitive lipase Clinical Science (1995) 89, 421-429 (Printed in Great Britain) Effects of weight reduction on the regulation of lipolysis in adipocytes of women with upper-body obesity Signy REYNISDOTIIR, Dominique LANGIN*, Kjell CARLSTROMt, Cecilia HOLMt, Stephan ROSSNER...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (1995) 89 (1): 91–99.
Published: 01 July 1995
...E. H. Horn; J. A. Cooper; E. Hardy; S. Heptinstall; P. C. Rubin 1. Platelet behaviour in vitro in relation to cyclic AMP was studied longitudinally during pregnancy and in the same women when they were not pregnant. Subjects comprised a group of healthy primigravidae and a group of women deemed...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (1994) 86 (2): 133–139.
Published: 01 February 1994
.../l), Na + -poor (< 70 mmol/l) primary fluid as does the rat paw sweat gland, as previously reported. The methacholine-induced sweat rate increases with age in parallel with the growth of the sweat gland over the first 6 weeks of life. 3. The sweating response to cyclic AMP-elevating agents...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (1993) 84 (6): 581–584.
Published: 01 June 1993
...John B. Warren © 1993 The Biochemical Society and the Medical Research Society 1993 cyclic AMP endothelium inflammation microcirculation nitric oxide oedema permeability vasodilatation Clinical Science (1993) 84, 581-584 (Printed in Great Britain) Editorial Review 581 Vascular...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (1993) 84 (2): 151–157.
Published: 01 February 1993
...Ian P. Hall; Keri Daykin; Sophie Widdop 1. The mechanisms underlying control of cyclic AMP responses to isoprenaline were studied in primary cultures of human airway smooth muscle cells. In these cells, isoprenaline induced concentration-related cyclic AMP formation via β 2 -adrenoceptor...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (1991) 80 (6): 549–558.
Published: 01 June 1991
.... The cyclic nucleotide cyclic AMP has a key role as an inhibitory second messenger in platelets and mediates the inhibitory effects of prostacyclin. 2. We have studied cyclic AMP in relation to platelet behaviour in healthy pregnant women in the third trimester and in women with pregnancy-induced hypertension...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (1986) 70 (4): 353–357.
Published: 01 April 1986
... observed in the renal papillae of the rat in terms of both agonist and antagonist potencies. 8 8 1985 28 10 1985 © 1986 The Biochemical Society and the Medical Research Society 1986 adenosine cyclic AMP renal papilla Clinical Science (1986) 70,353-357 353 Adenosine receptors...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (1984) 66 (5): 557–559.
Published: 01 May 1984
... plasma levels of adenosine 3′:5′-cyclic monophosphate (cyclic AMP) after an intravenous injection of glucagon in eight patients receiving long term lithium treatment and in six control subjects. Urinary cyclic AMP levels after an intravenous injection of bovine parathyroid hormone (PTH) were also...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (1983) 64 (6): 623–627.
Published: 01 June 1983
...D. G. Waller; J. D. M. Albano; J. G. B. Millar; A. Polak 1. Urinary and plasma levels of adenosine 3′:5′-cyclic monophosphate (cyclic AMP) after an intravenous injection of bovine parathyroid hormone (PTH) were measured in 12 patients on long-term lithium treatment and in nine control subjects...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (1983) 64 (3): 355–358.
Published: 01 March 1983
...Ricardo Exequiel Chatelain 1. To determine the possible role of arterial cyclic AMP in the pathogenesis of hypertensive vascular hypertrophy and hyperplasia, the changes in the level of this nucleotide were studied during the development of renal hypertension in rats with aortic ligation between...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (1981) 60 (5): 579–585.
Published: 01 May 1981
... of partial β-adrenoceptor blockade. 3. After 4 weeks' salbutamol therapy the airway response to intravenous salbutamol was unchanged. 4. The glucose, pyruvate and adenosine 3′:5′-cyclic monophosphate (cyclic AMP) responses to intravenous salbutamol were depressed after regular salbutamol administration...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (1981) 60 (5): 587–589.
Published: 01 May 1981
...′-cyclic monophosphate (cyclic AMP) with a competitive binding assay. 2. The two groups did not differ significantly in the levels of cyclic AMP produced or in the concentration of isoprenaline required to give half-maximal stimulation of the cells (ED 50 ). 5 8 1980 5 11 1980 20 1 1981...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (1980) 59 (s6): 247s–249s.
Published: 01 December 1980
...I. Kobrin; R. Ebstein; D. Ben-Ishay 1. The noradrenaline-induced accumulation of cyclic AMP is decreased in both the anterior and the posterior hypothalamus of hypertension-prone as compared with resistant rats, but is similar in the cortex. 2. The nonadrenaline-induced accumulation of cyclic AMP...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (1980) 59 (s6): 91s–94s.
Published: 01 December 1980
... which maximally stimulated aldosterone significantly increased cyclic AMP production, maximally stimulating doses of sheep β-lipotropin did not increase cyclic AMP production significantly. 4. These data suggest that β-lipotropin may play a role in aldosterone regulation through a mechanism different...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (1980) 59 (3): 199–201.
Published: 01 September 1980
...P. Arner; J. Östman 1. The activation of lipolysis on incubation of human subcutaneous adipose tissue was examined in terms of the relationship between the release of glycerol and the concentration of tissue cyclic AMP. 2. A strong positive correlation was obtained between the maximum concentration...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (1980) 58 (3): 201–210.
Published: 01 March 1980
... resorption breast cancer cyclic AMP hypercalcaemia kidney cancer prostaglandins Clinical Science (1980) 58.201-210 Prostaglandins as mediators of bone resorption in renal and breast tumours M. GREAVES, K. J . IBBOTSON, D. A T K I N S AND T. J. M A R T I N Departments of Chemical Pathology...
Articles
Journal:
Clinical Science
Clin Sci (Lond) (1980) 58 (1): 59–63.
Published: 01 January 1980
...J. P. D. Reckless; D. J. Galton 1. The concentrations of adenosine 3′:5′-cyclic monophosphate (cyclic AMP) in human adipose tissue were studied after intravenous insulin administration (0·3 unit/kg body weight) in obese diabetic and obese non-diabetic subjects. 2. The declines in plasma glucose...
Articles
Journal:
Clinical Science
Clin Sci Mol Med (1978) 54 (5): 573–577.
Published: 01 May 1978
...K. Kurokawa; E. Aznar; C. Descoeudres; Anicia Zulueta; S. G. Massry 1. The effects of adrenalectomy on the adenylate cyclase—adenosine 3′:5′-cyclic monophosphate (cyclic AMP) system of rat renal medulla were examined to evaluate the mechanism of the impaired water diuresis in glucocorticoid...
Articles
Journal:
Clinical Science
Clin Sci Mol Med (1977) 53 (5): 431–438.
Published: 01 November 1977
... before the operation. In all cases there was a rise in T m,P /GFR, though not all values were normalized. 4. Changes in plasma parathyroid hormone, T m,P /GFR and plasma and urinary cyclic AMP concentrations were measured during infusion of bovine parathyroid hormone into normal fasting subjects...
Articles
Journal:
Clinical Science
Clin Sci Mol Med (1976) 51 (1): 59–69.
Published: 01 July 1976
...S. Tomlinson; G. N. Hendy; D. M. Pemberton; J. L. H. O'Riordan 1. Normal subjects showed a highly reproducible, rapid increase in plasma adenosine 3′:5′-cyclic monophosphate (cyclic AMP) after an intravenous injection of 200 MRC units of highly purified bovine parathyroid hormone. 2. No significant...
Articles
Journal:
Clinical Science
Clin Sci Mol Med (1976) 50 (6): 487–491.
Published: 01 June 1976
..., though not significant, decrease in plasma cyclic AMP at 15 min followed by an increase to more than twice the initial concentration at 30 min. The increase was absent when hypoglycaemia was lessened by infusion of glucose after insulin injection. 3. Injection of insulin caused no significant change...
Articles
Journal:
Clinical Science
Clin Sci Mol Med (1974) 47 (5): 481–492.
Published: 01 November 1974
...S. Tomlinson; P. M. Barling; J. D. M. Albano; B. L. Brown; J. L. H. O'Riordan 1. Administration of highly purified bovine parathyroid hormone (BPTH) (200 MRC units) increased the concentration of adenosine 3′,5′-cyclic monophosphate (cyclic AMP) in the peripheral plasma of normal subjects within...
Articles
Journal:
Clinical Science
Clin Sci Mol Med (1974) 46 (3): 307–309.
Published: 01 March 1974
...F. S. Barnes; Elfriede Gamow; Anne Burns; Ann De Boisfleury 1. Platelets undergo a spreading reaction in a microscope slide—coverslip preparation. 2. If a gradient of cyclic AMP is generated in such a preparation a large fraction of the spread platelets are oriented with their veils...
Articles
Journal:
Clinical Science
Clin Sci Mol Med (1974) 46 (1): 75–87.
Published: 01 January 1974
...G. Jerums; D. J. Galton; C. Gilbert 1. Isoprenaline (1 μmol/l) and glucagon (1 μmol/l) raised the levels of cyclic AMP in isolated adipose cells of the rat to a maximum after incubation for approximately 15 min. 2. The effect of glucagon was impaired by pretreatment of adipose cells with trypsin...
Articles
Journal:
Clinical Science
Clin Sci Mol Med (1973) 45 (s1): 247s–250s.
Published: 01 August 1973
...G. Anglès D'Auriac; P. Meyer 1. Intracellular concentrations of adenosine 3′: 5′-cyclic phosphate (cyclic AMP) and activities of adenylcyclase and phosphodiesterase were determined in oestrogen-pretreated rat uteri during exposure to different concentrations of angiotensin II. 2. No significant...
