...Dirk Bokemeyer; Ursula Friedrichs; Angela Bäcker; Sabine Drechsler; Herbert J. Kramer; Harald Meyer-Lehnert 1. As we have previously shown, cyclosporin A enhances the vasoconstrictor-induced rise in intracellular free calcium in vascular smooth muscle cells. This effect may contribute to important...

...Nigel D.C. Sturrock; A.D. Struthers Clinical Science (1994) 86, 1-9 (Printed in Great Britain) I Editorial Review Hormonal and other mechanisms involved in the pathogenesis of cyclosporin-induced nephrotoxicity and hypertension in man Nigel D.C. STURROCK and A.D. STRUTHERS* Diabetes Unit, Queen s...

...M. S. Markell; B. T. Altura; R. L. Barbour; B. M. Altura 1. Ionized magnesium, measured using a newly developed ion-selective electrode, total magnesium, and ionized and total calcium were evaluated in 39 stable, long-term, cyclosporin-treated renal transplant recipients and compared with those...

...A. M. Peters; J. Z. Heckmatt; N. Hasson; B. L. Henderson; D. EL-Meleigy; M. L. Rose; V. Dubowitz 1. Renal haemodynamics were monitored over an average period of 19 months in 17 children being treated with cyclosporin A. Sixteen had juvenile dermatomyositis and one had chronic polyneuropathy...

...Norman L. M. Wong; John H. Dirks 1. Twenty-four hour clearance studies were performed on three groups of rats to determine the hypomagnesaemic effect of cyclosporin. Group I rats served as controls, whereas group II rats received 10 mg of cyclosporin/kg and group III rats received 20 mg...