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Keywords: cystic fibrosis
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Clin Sci (Lond) (1994) 86 (2): 133–139.
Published: 01 February 1994
... the sweating occurred in response to cyclic AMP-elevating agonists, we speculate that the cyclic AMP-activated Cl − channels (the mouse version of the cystic fibrosis transmembrane conductance regulator) may also occur in the mouse sweat gland, but that the degree of their expression may be influenced...
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Clin Sci (Lond) (1992) 82 (6): 667–672.
Published: 01 June 1992
...S. N. Smith; E. W. F. W. Alton; D. M. Geddes 1. The basic defect in cystic fibrosis relates to abnormalities of ion transport in affected tissues, such as the respiratory and gastrointestinal tracts. The identification of the cystic fibrosis gene has enabled studies on the production of a cystic...
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Clin Sci (Lond) (1990) 79 (4): 299–305.
Published: 01 October 1990
... hyperfiltration in essential fatty acid-deficient rats with the subsequent fall in glomerular filtration rate, which was paralleled by a rise in serum levels of urea and creatinine, as well as the increased non-renal clearance of tobramycin, are in accordance with the clinical manifestations of cystic fibrosis...
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Clin Sci (Lond) (1990) 78 (4): 409–417.
Published: 01 April 1990
... patients with cystic fibrosis and asthma. 2. In carcinoma controls, mean B max. values (± sem ) for airway levels 1 and 11 were 89 ± 4 and 133 ± 6 fmol/mg of protein, respectively ( P <0.01). The corresponding K D values at each airway level were similar, i.e. 29 ± 2 and 33 ± 1 pmol/l, respectively...
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Clin Sci (Lond) (1987) 73 (4): 407–410.
Published: 01 October 1987
...Ross D. Feldman; Robert B. Fick; Wendy McArdle; Cynthia C.-Y. Lai 1. β-Adrenergic responsiveness may be decreased in cystic fibrosis. In order to determine whether this reflects an alteration in the human lymphocyte β-receptor complex, we studied 12 subjects with cystic fibrosis (six were stable...
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Clin Sci (Lond) (1985) 68 (4): 441–447.
Published: 01 April 1985
.... The composition of thermal and pilocarpine sweat indicates that pharmacological stimulation does not wholely reproduce the physiological mechanism: pilocarpine sweat contains more sodium and more cyclic AMP, irrespective of the secretory rate. 3. The sweat obtained from patients with cystic fibrosis has been...
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Clin Sci (1972) 43 (4): 533–543.
Published: 01 October 1972
... in the former and inversely proportional in the latter case. 4. Sympathomimetic drugs, bradykinin and mucolytic drugs had no effect on the secretory index. 5. In cystic fibrosis, bronchitis and bronchiectasis gland size and not the disease process was the main determinant of the secretory index. 30 5 1972...