..., and biliverdin reductase, which reduces biliverdin to UCB (unconjugated bilirubin). UCB exerts both cytoprotective and cytotoxic effects in a variety of tissues and cells, acting either as an antioxidant at low concentrations or as an oxidant at high concentrations. In the present review, we describe in detail...

.... This has led to interest in the use of this class of drugs outside the realm of cardiovascular disease. cytoprotection endothelium 3-hydroxy-3-methylglutaryl-CoA (HMG-CoA) reductase inflammation pleiotropic effect statins Correspondence: Dr Justin Mason (e-mail [email protected]...

... aminotransferase levels (37 ± 4 compared with 23 ± 9 μmol/l in animals not given CCl 4 ) and had no significant rise in malondialdehyde levels. 4. EGF protects against CCl 4 -induced hepatic injury and may provide a novel approach to the treatment of liver damage. Cytoprotection hepatitis Clinical Science...

...W. D. W. Rees; L. A. Turnberg © 1982 The Biochemical Society and the Medical Research Society 1982 alkali secretion cytoprotection gastric mucosa prostaglandins Clinical Science (1982) 6% 343-348 343 EDITORIAL REVIEW Mechanisms of gastric mucosal protection: a role for the mucus...