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Keywords: db/db mice
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Articles
Marcondes Alves B. Silva, Stefany Bruno A. Cau, Rheure Alves M. Lopes, Carla P. Manzato, Karla B. Neves, Thiago Bruder-Nascimento, Fabiola Leslie Antunes C. Mestriner, Augusto C. Montezano, Aurelie Nguyen Dinh Cat, Rhian M. Touyz, Rita C. Tostes
Journal:
Clinical Science
Clin Sci (Lond) (2015) 129 (7): 533–545.
Published: 03 July 2015
... of MR in this process needs further studies. Thus, we tested the hypothesis that MR, through redox-sensitive mechanisms, plays a role in diabetes-associated vascular remodelling. Male, 12–14-weeks-old db/db mice, a model of type 2 diabetes and their non-diabetic counterpart controls (db/+) were treated...
Articles
Rui Xi Li, Wai Han Yiu, Hao Jia Wu, Dickson W. L. Wong, Loretta Y. Y. Chan, Miao Lin, Joseph C. K. Leung, Kar Neng Lai, Sydney C. W. Tang
Journal:
Clinical Science
Clin Sci (Lond) (2015) 128 (4): 269–280.
Published: 17 October 2014
... and reactive oxygen species production in PTECs. Compared with vehicle control, uninephrectomized db / db mice treated with BMP7 for 8 weeks had significantly lower urinary albumin-to-creatinine ratio (3549±816.2 μg/mg compared with 8612±2037 μg/mg, P =0.036), blood urea nitrogen (33.26±1.09 mg/dl compared...