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Keywords: db/db mouse
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Articles
Renoprotective effects of a novel Nox1/4 inhibitor in a mouse model of Type 2 diabetes
Available to PurchaseMona Sedeek, Alex Gutsol, Augusto C. Montezano, Dylan Burger, Aurelie Nguyen Dinh Cat, Chris R. J. Kennedy, Kevin D. Burns, Mark E. Cooper, Karin Jandeleit-Dahm, Patrick Page, Cedric Szyndralewiez, Freddy Heitz, Richard L. Hebert, Rhian M. Touyz
Journal:
Clinical Science
Clin Sci (Lond) (2013) 124 (3): 191–202.
Published: 17 October 2012
... Society 2013 db / db mouse diabetes kidney NADPH oxidase NOX inhibitor oxidative stress • Increased Nox-derived ROS production has been implicated in experimental and human diabetic nephropathy. Of the Nox isoforms, Nox4 is abundant in the kidney and may be important in renal...
Includes: Supplementary data
