...Laura Marongiu; Mihai Valache; Fabio A. Facchini; Francesca Granucci The ability of dendritic cells (DCs) to sense viral pathogens and orchestrate a proper immune response makes them one of the key players in antiviral immunity. Different DC subsets have complementing functions during viral...

...Morley D. Hollenberg This commentary deals with the new observations that dendritic cell (DC) oxytocin receptors play a role in the inflammatory response generated in murine animal models of colitis. The overview provides a context of the discovery of oxytocin (OT), its chemical synthesis...

... indicated that the neurosecretory hormone oxytocin (OXT) has been proven to alleviate experimental colitis. Methods: We investigated the role of OXT/OXT receptor (OXTR) signalling in dendritic cells (DCs) using mice with specific OXTR deletion in CD11c + cells (OXTR flox/flox ×CD11c-cre mice) and a dextran...

.... In their article in Clinical Science , Krishna et al. have reported that depletion of CD11c + dendritic cells inhibited experimental AAA formation in mice. The authors also demonstrated a decrease in CD4 and CD8 positive T cells in the circulation, lower plasma neutrophil elastase activity, and aortic matrix...

...Smriti M. Krishna; Corey S. Moran; Roby J. Jose; Sharon Lazzaroni; Pacific Huynh; Jonathan Golledge Objective: The role of chronic inflammation in abdominal aortic aneurysm (AAA) is controversial. CD11c + antigen-presenting cells (APCs) (dendritic cells (DCs)) have been reported in human AAA...

... dendritic cells immune response preeclampsia T-cells vasopressin Roles for AVP in the regulation of blood pressure and fluid homeostasis are generally accepted, however, a role for AVP in immune system function is less well appreciated. AVP secretion stimulates pro-inflammatory cytokine...

..., adhesion, and survival. In the liver, CX 3 CR1 is expressed on multiple cell types including monocytes and dendritic cells. However, the function of CX 3 CR1 on hepatic dendritic cells (HDCs) is still poorly understood. In the present study, we investigated the role of CX 3 CR1 on mouse HDCs during...

... endoscopic biliary drainage. Dendritic cell (DC) subsets and their expression of co-stimulatory molecules were also studied. Forty patients with OJ and ten non-jaundiced patients with normal gastroscopy findings were recruited. Ten healthy volunteers provided control blood samples for immunological assays...

...Salvatore Sutti; Irene Locatelli; Stefania Bruzzì; Aastha Jindal; Marco Vacchiano; Cristina Bozzola; Emanuele Albano Liver monocytes play a major role in the development of NASH (non-alcoholic steatohepatitis). In inflamed tissues, monocytes can differentiate in both macrophages and dendritic cells...

... is not clear. In the present study, we investigated the generation of different Th responses by human dendritic cells (DCs) in MS. We compared the production of several Th cytokines by naive CD4 + T-cells polarized with myeloid and plasmacytoid DCs (mDCs and pDCs) in healthy donors (HD) and relapsing–remitting...