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Keywords: diabetes mellitus
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Clin Sci (Lond) (2016) 130 (13): 1105–1114.
Published: 23 May 2016
... hormone important during exercise. adipose tissue diabetes mellitus type 2 lipolysis natriuretic peptides obesity Total AT RNA was isolated using the TRIzol® reagent (Invitrogen). Reverse transcription of 300 ng of total RNA was performed using iScript cDNA synthesis kit (Bio-Rad...
Includes: Supplementary data
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Clin Sci (Lond) (2015) 128 (4): 269–280.
Published: 17 October 2014
... of Nephrology Renal Week held in Atlanta, GA, U.S.A., on 7–10 November 2013, and subsequently published in abstract form [ 30a ]. advanced glycation end-product diabetes mellitus db / db mice renal tubular cell • ESRD from T2DN imposes a heavy burden on most healthcare systems...
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Clin Sci (Lond) (2011) 121 (7): 305–312.
Published: 07 June 2011
...Ting-I Lee; Yu-Hsun Kao; Yao-Chang Chen; Nan-Hung Pan; Yung-Kuo Lin; Yi-Jen Chen Hypertension and DM (diabetes mellitus) are common chronic disorders that often co-exist. DM and PPAR (peroxisome-proliferator-activated receptor)-γ agonists may directly impair heart function. However, the effects...
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Clin Sci (Lond) (2010) 119 (10): 423–429.
Published: 05 August 2010
...Martin G. Lazenby; Martin A. Crook About a decade ago, a hypothesis was proposed suggesting that the innate immune system, including acute-phase reactants, contribute to the development of T2DM [Type 2 DM (diabetes mellitus)] and the metabolic syndrome. In this model, it was hypothesized...
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Clin Sci (Lond) (2010) 119 (6): 225–238.
Published: 08 June 2010
... of the endothelium and the onset of inflammation have not specifically been studied in diabetic arteriogenesis, production of MCP-1 has been investigated. arteriogenesis collateral circulation diabetes mellitus endothelium peripheral arterial disease vascular smooth muscle DM is recognized...
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Clin Sci (Lond) (2006) 110 (6): 665–671.
Published: 15 May 2006
..., but this did not influence myocardial infarct size. The Biochemical Society 2006 diabetes mellitus diet ischaemia/reperfusion injury metabolic syndrome myocardial infarction obesity T2DM (Type II diabetes mellitus) is the most common form of diabetes [ 1 ]. It has a strong polygenic...
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Clin Sci (Lond) (2005) 109 (2): 143–159.
Published: 25 July 2005
... 2005 15 3 2005 11 5 2005 The Biochemical Society 2005 diabetes mellitus endothelial dysfunction hyperglycaemia insulin resistance metabolic syndrome oxidative stress vascular complication Diabetes mellitus is a common metabolic disease worldwide affecting approx. 150...
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Clin Sci (Lond) (2004) 106 (5): 527–533.
Published: 01 May 2004
...-up clinic, at concentrations from 1 9 mmol · l 1. Glucose was also Key words: airway surface liquid, diabetes mellitus, glucose, hyperglycaemia, nasal. Abbreviations: OGTT, oral glucose tolerance test; SGLT, sodium/glucose co-transporter. Correspondence: Dr Emma Baker (e-mail [email protected]...
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Clin Sci (Lond) (2004) 106 (1): 53–60.
Published: 01 January 2004
...Zhi You FANG; Rodel LEANO; Thomas H. MARWICK Subclinical left ventricular (LV) dysfunction may be identified by reduced longitudinal contraction. We sought to define the effects of subclinical LV dysfunction on radial contractility in 53 patients with diabetes mellitus with no LV hypertrophy...
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Clin Sci (Lond) (2003) 105 (5): 537–540.
Published: 01 November 2003
... 2003 The Biochemical Society 2003 diabetes mellitus stress echocardiography tissue Doppler ventricular function Clinical Science (2003) 105, 537 540 (Printed in Great Britain) 537 C O M M E N T Ventricular dysfunction in early diabetic heart disease: detection, mechanisms and significance...
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Clin Sci (Lond) (2002) 103 (s2002): 424S–429S.
Published: 01 September 2002
...Eugene L. BEK; Marvin A. MCMILLEN; Paul SCOTT; L. D. George ANGUS; Gerald W. SHAFTAN In diabetes mellitus, there is a problem of both premature atherosclerosis as well as impaired collateralization. Studies were performed using the rat corneal angiogenesis model as a surrogate for collateralization...
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Clin Sci (Lond) (2001) 101 (6): 671–679.
Published: 21 November 2001
... difficult in the absence of diabetes-specific risk equations. The model for CHD risk in Type II diabetes Key words: coronary disease, diabetes mellitus, models, non-insulin-dependent, statistical. Abbreviations : CHD, coronary heart disease ; DCCT, Diabetes Control and Complications Trial ; GDM, Global...
Includes: Supplementary data
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Clin Sci (Lond) (2000) 99 (5): 383–392.
Published: 03 October 2000
...R. Andrew P. SKYRME-JONES; Richard C. O'BRIEN; Ian T. MEREDITH We and others have previously documented increased resting and exercise-induced skeletal muscle blood flow in young subjects with Type I (insulin-dependent) diabetes mellitus compared with healthy controls. Both NO and prostanoids...
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Clin Sci (Lond) (2000) 98 (3): 355–363.
Published: 10 February 2000
... by retinopathy. Correspondence : Dr B. Mackness (e-mail [email protected] ). 26 7 1999 27 10 1999 9 12 1999 The Biochemical Society and the Medical Research Society © 2000 2000 diabetes mellitus paraoxonase polymorphisms retinopathy 355Clinical Science (2000...
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Clin Sci (Lond) (2000) 98 (2): 175–181.
Published: 11 January 2000
... with ischaemic heart disease ( n = 80), cardiac arrhythmia ( n = 60), diabetes mellitus ( n = 36), essential hypertension ( n = 194) and hypercholesterolaemia ( n = 60). The same measurements were made in healthy controls (30 men and 26 women; mean age 58±11 years). The serum ionized Mg concentration...
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Clin Sci (Lond) (1999) 97 (2): 149–156.
Published: 16 June 1999
... in patients with diabetes is associated with their total insulin exposure to see if plasma ET-1 might be a link between insulin exposure and long-term complications of diabetes. We studied 69 patients with Type I and 40 patients with Type II diabetes mellitus in equally tight glycaemic control for 2 years...
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Clin Sci (Lond) (1999) 96 (3): 221–230.
Published: 01 March 1999
...Tahseen A. CHOWDHURY; Philip H. DYER; Sudhesh KUMAR; Anthony H. BARNETT; Stephen C. BAIN Diabetic nephropathy is the most serious complication of diabetes mellitus. Progression of the condition leads to end-stage renal failure, and other complications of diabetes are also common in this group...
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Clin Sci (Lond) (1998) 95 (3): 317–323.
Published: 01 September 1998
...Anders O. BJÖRKLUND; Ulf K. C. ADAMSON; Per-Eric S. LINS; L. Magnus R. WESTGREN 1. Intensive insulin treatment of patients with Type I diabetes mellitus during pregnancy is associated with a high frequency of serious hypoglycaemic events. A potential change in insulin metabolism during pregnancy...
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Clin Sci (Lond) (1998) 94 (6): 623–632.
Published: 01 June 1998
...Rakesh Kakkar; Subrahmanyam V. Mantha; Jasim Radhi; Kailash Prasad; Jawahar Kalra 1. Oxygen free radicals have been suggested to be a contributory factor in complications of diabetes mellitus. There are many reports indicating the changes in parameters of oxidative stress in diabetes mellitus...
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Clin Sci (Lond) (1998) 94 (2): 157–163.
Published: 01 February 1998
... three measures of cerebral function during hypoglycaemia [7]. Having demonstrated a globally protective effect of lactate on cerebral function in non-diabetic sub- jects, we have extended our study to subjects with insulin-dependent diabetes mellitus (IDDM), since it cannot be assumed...
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Clin Sci (Lond) (1998) 94 (1): 65–70.
Published: 01 January 1998
... between changes in blood pressure and the rate of gastric emptying after ingestion of 75 g of glucose in patients with noninsulin-dependent diabetes mellitus (NIDDM) and both young and older normal subjects. Sixteen patients with recently diagnosed NIDDM, median age 57 (39–79) years, 10 ‘young’ subjects...
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Clin Sci (Lond) (1997) 93 (4): 335–341.
Published: 01 October 1997
...Qiuping Zhang; Elisabeth Cavallero; Michael M. Hoffmann; Julian Cavanna; Andrea Kay; Aline Charles; Sylvie Braschi; Winfried Marz; Leon Perlemuter; Bernard Jacotot; David J. Galton 1. The common association of obesity, diabetes mellitus and hyperlipidaemia may have a primary aetiological basis...
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Clin Sci (Lond) (1997) 93 (2): 147–152.
Published: 01 August 1997
.... This alteration in blood pressure appears to be detectable in childhood and is amplified with age [4]. Impaired glucose tolerance and type 2 (non- insulin-dependent) diabetes mellitus (NIDDM) are also risk factors for cardiovascular disease and a strong link was found between their development and reduced weight...
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Clin Sci (Lond) (1996) 91 (5): 575–582.
Published: 01 November 1996
... by the glyoxalase system with reduced glutathione as co-factor. The concentration of reduced glutathione may be decreased by oxidative stress and by decreased in situ glutathione reductase activity in diabetes mellitus. A reduced concentration of reduced glutathione may predispose diabetic patients to oxidative...
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Clin Sci (Lond) (1996) 90 (5): 379–384.
Published: 01 May 1996
... oxide l-arginine diabetes mellitus nitric oxide synthase inhibitor nitrate nitrite streptozotocin Clinical Science (1996) 90, 37W84 (Printed in Great Britain) 379 Nitric oxide in streptozotocin-induced diabetes mellitus in rats Abed MAREE, Gari PEER, Adrian IAINA, Miriam BLUM, Yoram WOLLMAN...
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Clin Sci (Lond) (1995) 89 (5): 461–465.
Published: 01 November 1995
...Ole Gøtzsche; Ahmed Darwish; Lars Peter Hansen; Liv Gøtzsche 1. Insulin-dependent diabetes mellitus is a known risk factor for congestive heart failure and an early diastolic dysfunction has been described. In order to see if diabetes itself and not complications like hypertension, nephropathy...
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Clin Sci (Lond) (1995) 88 (2): 191–196.
Published: 01 February 1995
... 9 1994 12 10 1994 © 1995 The Biochemical Society and the Medical Research Society 1995 diabetes mellitus flow motion laser Doppler flowmetry neuropathy vasomotion Clinical Science (1995) 88, 191-196 (Printed in Great Britain) 191 Flow motion in peripheral diabetic neuropathy...
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Clin Sci (Lond) (1994) 86 (4): 383–390.
Published: 01 April 1994
...Carlo Beretta-Piccoli; Francesca Elshater-Zanetti; Sidney Shaw; Daniele Cusi; Peter Weidmann 1. Diabetes mellitus is associated with high body sodium, but the pathogenetic mechanism is still unknown. The possibility that an abnormal renal handling of sodium, an abnormal responsiveness of sodium...
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Clin Sci (Lond) (1994) 86 (3): 257–262.
Published: 01 March 1994
... Society and the Medical Research Society 1994 contractile dysfunction diabetes mellitus myocyte Clinical Science (1994) M, 257-262 (Printed in Great Britain) Contractile dysfunction in the diabetic-rat heart is an intrinsic abnormality of the cardiac myocyte Hideki OKAYAMA, Mareomi HAMADA...
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Clin Sci (Lond) (1993) 85 (1): 101–104.
Published: 01 July 1993
... are probably mediated by autonomic mechanisms which are stimulated by hypoglycaemia. anterior chamber of eye aqueous humour autonomic nervous system diabetes mellitus hypoglycaemia 5 2 1993 6 4 1993 © 1993 The Biochemical Society and the Medical Research Society 1993 Clinical...
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Clin Sci (Lond) (1993) 84 (4): 469–475.
Published: 01 April 1993
...-glucosaminidase alanine aminopeptidase alkaline phosphatase diabetes mellitus dipeptidyl aminopeptidase IV γ-glutamyl transpeptidase non-insulin-dependent diabetes urine Clinical Science (1993) 84, 469-475 (Printed in Great Britain) 469 Enzymuria in non-insulidependent diabetic patients: signs...
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