... of the Biochemical Society 2018 diagnosis ischemic stroke lncRNA microarray PBMC transient ischemic attack Stroke remains a leading cause of serious long-term disability worldwide, with strokes in more than 80% of patients attributed to brain ischemia [ 1 ]. Intracranial thrombosis...

... pathogenesis [ 22 – 24 ]. cardiac biomarkers circulating lncRNA coronary artery disease diagnosis long non-coding RNA • CAD is the major cause of death worldwide; a lot of patients with acute coronary syndrome or severe coronary stenosis have benefited from the improved therapeutic methods...

... future of these discoveries in diagnosis, prognosis and therapy of NSCLC. Both original and review articles published in English and fully available were searched for in PubMed ( http://www.ncbi.nlm.nih.gov/pubmed/advanced ) through use of the search term (miRNA OR microRNA OR miRNA-* OR microRNA...

... factor)-binding protein 2] levels. Final diagnosis and death during follow-up were adjudicated blinded to LTBP2 levels. AHF (acute heart failure) was the final diagnosis in 54% of patients. In both AHF ( P <0.001) and non-AHF ( P =0.015) patients, LTBP2 levels at presentation were significantly higher...

... reduction in total plasma cholesterol that resulted from the treatment was still evident 7 weeks after the initial treatment with the highest dosage. Lower dosages were also found to be efficacious. diagnosis hypertension kidney microRNA (miRNA) therapy translational research miRNAs...

... Biochemical Society 2011 diagnosis oesophageal squamous cell carcinoma (ESCC) microRNA miR-31 prognosis Three ESCC cell lines, EC9706 (established in our laboratory) [ 25 ], KYSE150 and KYSE510 (gifts from Dr Y. Shimada, First Department of Surgery, Kyoto University, Kyoto, Japan) [ 26...

...Iain B. Squire; Christopher P. Nelson; Leong L. Ng; David R. Jones; Kent L. Woods; Paul C. Lambert The diagnosis of diabetes and admission blood glucose concentration are associated with adverse outcome after acute coronary syndromes. We compared the relative association with survival after ST...

... to their use as therapeutic agents in cardiovascular disease. atrial natriuretic peptide brain natriuretic peptide diagnosis heart failure prognosis management treatment The cardiac natriuretic peptides, ANP and BNP (atrial and brain natriuretic peptides respectively), are hormones...

... The Biochemical Society 2004 diabetic cardiomyopathy diagnosis echocardiography molecular mechanism treatment The epidemic of obesity and sedentary lifestyle is projected to result in over 300 million people with diabetes mellitus by 2025 [ 1 ]. Cardiovascular disease is responsible for 80...

... in this issue of Clinical Science that urinary levels of N-BNP may be as useful as plasma levels for the discrimination of patients with and without heart failure. This raises the potential for a relatively simple urine test that could be used for the diagnosis of heart failure. Roles in prognostication...

...L. L. NG; S. GEERANAVAR; S. C. JENNINGS; I. LOKE; R. J. O'BRIEN In the present study, we assessed the use of urinary natriuretic peptides [N-terminal proatrial natriuretic peptide (N-ANP) and N-terminal pro-brain natriuretic peptide (N-BNP) and C-type natriuretic peptide (CNP)] in the diagnosis...

...Arzu ENSARI; Michael N. MARSH; Shethah MORGAN; Robert LOBLEY; D. J. UNSWORTH; Daphne KOUNALI; Peter T. CROWE; Jane PAISLEY; Kieran J. MORIARTY; John LOWRY The purpose of this study was to evaluate the use of rectal gluten challenge in the diagnosis of coeliac disease. A total of 103 patients...

... of infection. 5. Measurement of intercellular adhesion molecule-1 level may have a clinical role in rapidly confirming, or predicting, the likely diagnosis in cases of suspected neonatal infection. 18 10 1993 21 1 1994 14 2 1994 © 1994 The Biochemical Society and the Medical Research...

... The Biochemical Society and the Medical Research Society 1970 adenine phosphoribosyltransferase deficiency diagnosis Clinical Science (1988) 75,217-220 217 Adenine phosphoribosyltransferase deficiency: a simple diagnostic test J. L. MADDOCKS AND S. A. AL-SAFI University Department of Therapeutics...

... concentration when present, coupled with adrenal venous sampling, provided the best indicators of the presence of an aldosterone-producing adenoma. adenoma aldosterone diagnosis potassium primary aldosteronism sodium © 1982 The Biochemical Society and the Medical Research Society 1982 Clinfcal...