Skip Nav Destination
1-4 of 4
Keywords: diastolic dysfunctionClose
Clin Sci (Lond) (2021) 135 (19): 2265–2283.
Published: 13 October 2021
... HFpEF and the metabolic syndrome (MetS) suggests that dysregulated lipid metabolism could drive diastolic dysfunction and subsequent HFpEF. Herein we summarise recent advances regarding the pathogenesis of HFpEF in the context of MetS, with a focus on impaired lipid handling, myocardial lipid...
Clin Sci (Lond) (2017) 131 (10): 897–915.
Published: 04 May 2017
...) relaxation followed by LV contractile dysfunction. Post-mortem examination reveals that human diastolic dysfunction is closely associated with LV damage, including cardiomyocyte hypertrophy, apoptosis and fibrosis, with impaired coronary microvascular perfusion. The pathophysiological mechanisms underpinning...
Sebastiano Sciarretta, Francesco Paneni, Francesca Palano, Diana Chin, Giuliano Tocci, Speranza Rubattu, Massimo Volpe
Clin Sci (Lond) (2009) 116 (6): 467–477.
Published: 12 February 2009
...Sebastiano Sciarretta; Francesco Paneni; Francesca Palano; Diana Chin; Giuliano Tocci; Speranza Rubattu; Massimo Volpe Left ventricular diastolic dysfunction represents a frequent clinical condition and is associated with increased cardiovascular morbidity and mortality. Diastolic dysfunction...
Piyush M. Srivastava, Merlin C. Thomas, Paul Calafiore, Richard J. MacIsaac, George Jerums, Louise M. Burrell
Clin Sci (Lond) (2006) 110 (1): 109–116.
Published: 12 December 2005
... and/or systolic dysfunction) on echocardiography had anaemia compared with <5% of patients with normal echocardiographic findings. Most patients with anaemia had cardiac dysfunction (94%), with the major abnormality being diastolic dysfunction associated with an increased left ventricular mass and impaired...