... © 2023 The Author(s). 2023 This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . blood pressure digoxin migraine stroke The authors of the review...

... signaling may also control intracellular Ca 2+ concentration through the phosphorylation of L-type calcium channels (LTCC), leading to increased Ca 2+ influx [ 52 , 53 ]. Digoxin is a Na,K-ATPase inhibitor that is used in clinical settings to regulate cardiac frequency and potentiate the cardiac...

... for measuring nasal potential difference, a pilot study was carried out using topical amiloride, a drug which has previously been shown to inhibit airway epithelium sodium transport in vivo. We then studied the effects of ouabain and digoxin, two inhibitors of Na + -K + -ATPase, and salbutamol, a drug which...

... trachealis. 2. To determine whether such drugs alter bronchial reactivity in vivo , we have studied the effect of oral digoxin (an inhibitor of Na + /K + -adenosine triphosphatase) and oral and inhaled amiloride on bronchial reactivity to histamine in three double-blind, placebo-controlled studies. 3...

...S. M. Pomfret; C. R. W. Beasley; V. Challenor; S. T. Holgate 1. The efficacy of verapamil alone, or in combination with digoxin, was compared with digoxin alone in eight patients with chronic atrial fibrillation in this double-blind placebo-controlled study. 2. After 2 weeks on each treatment...

... concentration are related to the distribution of rubidium to all the body tissues and the changes in intra-erythrocytic rubidium concentrations provide an example of rubidium uptake by one particular tissue. 2. In eight healthy volunteers pretreatment with a loading dose of digoxin (20 μg/kg) enhanced the rise...

... between the total activity of the sodium pumps and the membrane permeability to sodium. 3. Changes in the erythrocyte sodium content were due to a decrease in the activity of the sodium pumps (as in hypokalaemia and digoxin treatment), or a decrease in the permeability of the erythrocyte membrane...

...R. Lindsay; J. L. W. Parker 1. The effect of treating rats with digoxin and thyroxine for 45 days has been studied. 2. Animals fed with digoxin gained significantly more weight than the control animals. 3. Treatment with digoxin, thyroxine or both produced a similar significant increase...

...B. Beermann; K. Hellström; A. Rosén 1. [12α- 3 H]Digoxin and polyethylene glycol (nonabsorbable marker) dissolved in water were administered orally to five healthy subjects. 2. The ratio between the amount of radioactivity/mg of polyethylene glycol in gastro-intestinal aspirates...

...R. I. Ogilvie; G. A. Klassen 1. The forearm perfusion technique was used to study the effect of intra-arterial injections of ethanol with or without digoxin on the metabolism and electrolyte flux of forearm tissues in normal male volunteers. 2. In six subjects infusion of ethanol alone (2·9 mg/min...