... and its neuronal metabolite dihydroxyphenylglycol. A control group of 44 subjects included 10 elderly normal volunteers, 10 patients with Alzheimer's disease, 18 patients with dysautonomia (postural tachycardia syndrome or neurocardiogenic syncope) and six patients with MSA in the absence of OH. Patients...

... provide an extraordinarily sensitive method for diagnosis of phaeochromocytoma. 9 1 1995 17 1 1995 © 1995 The Biochemical Society and the Medical Research Society 1995 adrenal glands adrenalectomy adrenaline catechol- O -methyltransferase dihydroxyphenylglycol heart failure...

...Graeme Eisenhofer; Murray D. Esler; Ian T. Meredith; Claudia Ferrier; Gavin Lambert; Garry Jennings 1. Plasma concentrations of [ 3 H]dihydroxyphenylglycol, the intraneuronal metabolite of noradrenaline, were examined during intravenous infusion of [ 3 H]noradrenaline in 43 subjects, to assess...

...Graeme Eisenhofer; David S. Goldstein; Irwin J. Kopin 1. Neuronal re-uptake is the primary means for terminating the actions of endogenously released noradrenaline. A portion of the recaptured noradrenaline is deaminated to form dihydroxyphenylglycol. The present report describes a technique using...