... resuscitability after administration of calcium-entry blockers during cardiac arrest is incomplete. We therefore compared the effects of verapamil (0.05 mg/kg) and diltiazem (0.075 mg/kg) with those of saline placebo in an established porcine model of cardiac arrest and cardiopulmonary resuscitation. 2. After...

... renin release. Exposure to 0.06 mmol/l Ca 2+ increased release by 120% ( P < 0.001) when presented as the first buffer in ascending order of concentration and by 79% ( P < 0.001) when presented as the fourth and last in a series of descending order. 3. The Ca 2+ entry blocking drug diltiazem...

...-aminolaevulinate synthase and accumulation of porphyrins with uroporphyrin and heptacarboxylic porphyrin predominating. 2. Diltiazem, another calcium channel blocking drug, did not affect uroporphyrinogen decarboxylase activity and had a slight effect only on the accumulation of porphyrins. 3. Experiments...

...Yoshinori Kawaguchi; Kyuzo Aoki; Masahiko Yamamoto; Ken Hotta 1. Calcium reactivity of arterial smooth muscle and the effect of diltiazem (calcium antagonist) were investigated in helical strips of mesenteric arteries from 6-week-old male spontaneously hypertensive rats (SHR) and age-and sex...