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Keywords: diuretics
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Articles
Clin Sci (Lond) (2004) 106 (1): 27–34.
Published: 01 January 2004
... contribute to platelet aggregation and to maintain the response to diuretics in advanced cirrhosis. In the present study, we tested the effects of a dietary supplementation for 8 weeks with a triacylglycerol (triglyceride) enriched in AA (ARASCO®; 4 g/day) or oleic acid (OA) on plasma and membrane fatty acid...
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Clin Sci (Lond) (1999) 96 (6): 669–675.
Published: 12 May 1999
... pretreatment. Hydrochlorothiazide (10 -7 mol/l) significantly decreased 11β-HSD2 activity ( P < 0.05 compared with control) at 4 h pretreatment. Commonly used diuretics, atrial natriuretic peptide and physiological concentrations of angiotensin II and bradykinin do not alter 11β-HSD2 activity. In contrast...
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Clin Sci (Lond) (1996) 90 (1): 31–36.
Published: 01 January 1996
... was not affected by chlorothiazide treatment. Chlorothiazide therapy did not prevent or reverse cardiac hypertrophy. 4. Chronic diuretic therapy in this experimental model of heart failure did not reduce extracellular sodium, plasma vasopressin or the extent of ventricular hypertrophy, possibly because...
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Clin Sci (Lond) (1994) 86 (3): 353–357.
Published: 01 March 1994
...M. Hatch; N. D. Vaziri 1. The purpose of the present study was to examine the effects of various diuretics on intestinal oxalate transport. Transmural oxalate fluxes were measured across isolated, short-circuited tissue segments removed from rabbits and placed in Ussing chambers. 2. The net...
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Clin Sci (Lond) (1991) 81 (3): 335–340.
Published: 01 September 1991
... + retard stroke development by inducing natriuresis and facilitating the clearance of Na + , and that diuretics associated with natriuresis might also be capable of retarding stroke development in spSHR. To test if this was the case, the onset of stroke development in spSHR fed a low (0.75%) K + diet...
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Clin Sci (Lond) (1984) 67 (2): 195–203.
Published: 01 August 1984
... with that found during the high salt intake. In addition, low salt intake abolished the compensatory renal retention of K + after frusemide and cumulative K + balance over 3 days of diuretic administration was uniformly negative (−86 ± 7 mmol/3 days; P < 0.001). 4. Captopril abolished the rise in plasma...
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Clin Sci (Lond) (1983) 64 (3): 259–263.
Published: 01 March 1983
...Renzo Carretta; Bruno Fabris; Giuseppe Bellini; Laura Tonutti; Gabriella Battilana; Anna Bianchetti; Luciano Campanacci Summary 1. Baroreceptor sensitivity and vascular reactivity to noradrenaline were assessed in patients with essential hypertension chronically treated with diuretics during...
Articles
Clin Sci (Lond) (1982) 63 (5): 447–453.
Published: 01 November 1982
... in the regulation of renal water and sodium excretion as well as of renal plasma flow. 11 12 1981 13 5 1982 8 6 1982 © 1982 The Biochemical Society and the Medical Research Society 1982 diuretics frusemide kallikrein-kinin system kininogen kinins natriuresis renal plasma flow...
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Clin Sci (Lond) (1982) 63 (s8): 423s–425s.
Published: 01 October 1982
.... For the more severe hypertensive patients failure rate was considerably higher among the obese than the non-obese in each sex-race group. © 1982 The Biochemical Society and the Medical Research Society 1982 antihypertensive therapy, diet diuretics drugs Clinical Science (1982) 6 3 , 4 2 3 ~ 4 2 5...
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Clin Sci (Lond) (1982) 63 (2): 121–125.
Published: 01 August 1982
.... The diuretic was then discontinued and the measurements were repeated before and again after 7 days with bendrofluazide. The results were compared with those obtained before chronic treatment with the diuretic. 2. Chronic diuretic treatment was associated with a persistent and progressive rise in plasma renin...
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Clin Sci (Lond) (1982) 62 (2): 235–238.
Published: 01 February 1982
... but is associated with a resistance to the action of vasopressin. chlorthiazide diuretics frusemide hyponatraemia oedema sodium © 1982 The Biochemical Society and the Medical Research Society 1982 6 7 1981 24 9 1981 Clinical Science (1982) 62,235-238 235 Comparative effect...
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Clin Sci (Lond) (1980) 59 (s6): 393s–395s.
Published: 01 December 1980
... ventricular performance. © 1980 The Biochemical Society and the Medical Research Society 1980 cardiac function cardiopulmonary blood volume diuretics nervous system sodium depletion Clinical Science (1980) 59,393s-395s 393s Alterations in cardiac function and cardiopulmonary blood volume...
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Clin Sci (Lond) (1980) 59 (1): 67–70.
Published: 01 July 1980
...H. J. Kramer; R. Düsing; B. Stinnesbeck; W. Prior; Angela Bäcker; Jutta Eden; J. Kipnowski; K. Glänzer; F. Krück 1. The effects of frusemide, hydrochlorothiazide and spironolactone on the renal prostaglandin system, and the interference with their diuretic and natriuretic effects by inhibition...
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Clin Sci (Lond) (1979) 57 (s5): 367s–369s.
Published: 01 December 1979
... receiving hydrochlorothiazide a slight increase in serum uric acid, with no modification of urate clearance, occurred. 4. The diuretic and antihypertensive actions of tienilic acid and hydrochlorothiazide are very similar. The uricosuric/hypouricaemic effect of tienilic acid could assume clinical relevance...
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Clin Sci (Lond) (1979) 57 (s5): 123s–125s.
Published: 01 December 1979
... The Biochemical Society and the Medical Research Society 1979 β-tadrenoreceptor blockers angiotensin II angiotensin II inhibitors diuretics hypertension renin Clinical Science (1979) 57.1238-125s Angiotensin I1 blockade during combined thiazideadrenoreceptor-blocker treatment H. IBSEN, A. LETH, A. M...
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Clin Sci Mol Med (1978) 55 (6): 555–559.
Published: 01 December 1978
...P. A. Poole-Wilson; S. M. Cobbe; C. H. Fry 1. We have studied the acute effects of frusemide, triamterene and amiloride on potassium exchange, the action potential and mechanical function of isolated rabbit myocardium. 2. Potassium exchange in the myocardium was unaltered by these diuretics. 3...
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Clin Sci Mol Med (1978) 55 (s4): 325s–328s.
Published: 01 December 1978
...Z. Glück; G. Baumgartner; P. Weidmann; E. Peheim; C. Bachmann; R. Mordasini; J. Flammer; G. Keusch 1. The effect of diuretic therapy on serum lipids and lipoprotein fractions was evaluated in 16 normal or labile hypertensive subjects who received in cross-over fashion chlorthalidone, frusemide...
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Clin Sci Mol Med (1978) 54 (6): 679–683.
Published: 01 June 1978
...B. A. Brooks; A. F. Lant 1. The Na + and Cl − transport systems of human erythrocytes have been compared for their sensitivities to diuretics known to act in the ascending limb of Henle's loop. In addition, chemical analogues of ‘loop’ compounds and also diuretics which act in other areas...
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Clin Sci Mol Med (1977) 52 (6): 631–634.
Published: 01 June 1977
... © 1977 The Biochemical Society and the Medical Research Society 1977 diuretics frusemide intracellular electrolytes muscle Clinical Science and Molecular Medicine (1977) 52,631-634. SHORT COMMUNICATION The effect of chronic fmemide administration on intracellular potassium, sodium and pH...
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Clin Sci Mol Med (1976) 51 (s3): 283s–286s.
Published: 01 December 1976
... with two-kidney Goldblatt hypertension. This group was also the only group that demonstrated a significant rise in plasma renin activity. © 1976 The Biochemical Society and the Medical Research Society 1976 bradykinin radioimmunoassay diuretics hypertension kallikrein—kinin renin—angiotensin...
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Clin Sci Mol Med (1976) 51 (s3): 571s–573s.
Published: 01 December 1976
... is a clonidine-like substituted imidazoline. © 1976 The Biochemical Society and the Medical Research Society 1976 anti-hypertensive treatment β-receptor-blocking agents diuretics Clinical Science and Molecular Medicine (1976) 51,571s-573s. Within-patient comparisons between different anti...
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Clin Sci Mol Med (1976) 51 (s3): 579s–581s.
Published: 01 December 1976
... mmHg. Concomitant therapy with β-receptor-blocking agents and diuretics resulted in satisfactory control of heart rate and weight gain. 3. Side effects included increased hair growth, nausea, fatigue, rash and darkening of the skin. ECG showed mainly T-wave changes and echocardiographic examination...
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Clin Sci Mol Med (1976) 51 (s3): 583s–585s.
Published: 01 December 1976
... with moderate hypertension control with minoxidil was achieved earlier and more easily than with hydrallazine. 4. Three patients developed secondary resistance and required addition of guanethidine or increased doses of diuretics. 5. Fluid retention and hypertrichosis were the main side effects with minoxidil...
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Clin Sci Mol Med (1976) 51 (s3): 257s–258s.
Published: 01 December 1976
.... Inhibition of prostaglandin secretion by indomethacin with restoration of responses to noradrenaline by the addition of exogenous prostaglandin E 2 prevented the inhibitory effect of frusemide or bumetanide on responses to noradrenaline. 4. The inhibitory effects of diuretics on responsiveness...
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Clin Sci Mol Med (1976) 51 (s3): 201s–202s.
Published: 01 December 1976
...M. P. Sambhi; J. D. Barrett; P. Eggena; C. Thananopavarn 1. Plasma renin activity and circulating amounts of blood angiotensin II were measured in twenty-six patients with uncomplicated essential hypertension. 2. Measurements were made during a control period and at 1, 4, 9 and 14 weeks of diuretic...
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Clin Sci Mol Med (1976) 51 (s3): 627s–629s.
Published: 01 December 1976
...A. S. P. Hua; Priscilla Kincaid-Smith 1. A cross-over study was done in twenty patients with hypertension to compare the effects of chlorothiazide (0·5 g twice daily) and metolazone (5 mg daily) in combination with other anti-hypertensive agents. 2. Compared with absence of diuretic therapy...
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Clin Sci Mol Med (1976) 51 (1): 9–17.
Published: 01 July 1976
... the initial cardiac index. 6. The association of a diuretic with sotalol enhanced the hypotensive effect of the beta-receptor blocking drug, without significant increase of plasma renin and angiotensin II concentrations. 24 11 1975 © 1976 The Biochemical Society and the Medical Research Society...
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Clin Sci Mol Med (1976) 50 (2): 91–102.
Published: 01 February 1976
... experiments performed by clearance methods in acid-loaded, conscious rabbits. 5. The results support the view that angiotensin may have an important intrarenal role, at least in rabbits. Key words: acid excretion, angiotensin, calcium, chloride, diuretics, electrolyte transport, hydrogen, magnesium, potassium...
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Clin Sci Mol Med (1975) 49 (6): 551–555.
Published: 01 December 1975
... volume depletion through diuresis and that increased plasma renin activity was mainly caused by intrarenal changes. 9 7 1975 © 1975 The Biochemical Society and the Medical Research Society 1975 diuretics frusemide haemodynamics haemoconcentration renin venous tone Clinical...
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Clin Sci Mol Med (1975) 49 (2): 107–113.
Published: 01 August 1975
... filtration rate was lower in the chlorothiazide-treated rats than in control rats and/or in the low-sodium group. End proximal tubule TF/P inulin ratios were higher in the diuretic-treated animals than in control rats. TF/P inulin ratios in low-sodium animals were lower than in the diuretic-treated animals...
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Clin Sci Mol Med (1975) 48 (s2): 215s–223s.
Published: 01 January 1975
... change has been established. 4. The effect of diuretics on renin release has been studied and evidence of neural and non-neural mechanisms obtained. 5. The effect of suprarenal aortic stenosis has been studied; the findings suggest that renin release is in some way dependent on neural mechanisms. 6...
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Clin Sci Mol Med (1975) 48 (s2): 189s–190s.
Published: 01 January 1975
...W. B. Martin; G. R. Zins; W. A. Freyburger 1. Minoxidil, an experimental arteriolar dilator, has been used in conjunction with a diuretic and a sympathetic nervous system suppressant in 510 patients with refractory hypertension, of whom 323 remain on treatment. The results in two of a total...
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Clin Sci Mol Med (1974) 46 (6): 671–678.
Published: 01 June 1974
...C. G. Duarte 1. The renal excretion of phosphate was studied in dogs under control conditions and during infusion of ethacrynic acid or frusemide at different levels of filtered load. 2. Both of these diuretic compounds significantly enhanced the fractional excretion of phosphate at normal...
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Clin Sci (1972) 42 (3): 265–275.
Published: 01 March 1972
... in the medulla than in the cortex. 4. Diuretic drugs inhibit activity in vitro only at high concentrations. 8 7 1971 © 1972 The Biochemical Society and the Medical Research Society 1972 adenosine triphosphatase kidney diuretics Clinical Science (1972) 42,265-275. DISTRIBUTION A N D...