...) or dobutamine ( n =14) infusion. Plasma IL-6, IL-18, sICAM, E-selectin, hs-CRP and oxidative markers were significantly higher in patients on admission before inotropic treatment compared with controls ( P <0.05). Short-term inotropic support improved clinical status as assessed by NYHA classification...

... dobutamine and during esmolol infusion. In normal perfused hearts, SR SYS (4.8±0.2 s -1 at baseline) increased during dobutamine infusion, decreased during esmolol infusion and correlated significantly with global E ES . In addition, ε SYS averaged 93±3% at baseline and there was almost no ε PST (4±1...

... differentiate between sympathetic stimulation induced by inotrope infusion or by physical exercise. 2. Ten patients with chronic heart failure (64.3 ± 5.4 years of age) underwent four dobutamine infusions (8-min steps of 5 μg min −1 kg −1 ) and four supine bicycle exercise tests (5-min steps of 25 W). Plasma...

...), atropine (1.2 mg; eight patients) or dobutamine (360 μg/min; six patients). 4. Isoprenaline and atropine caused a similar increase in heart rate (isoprenaline + 27 beats/min; atropine + 20 beats/min) but after dobutamine there was little change in heart rate (+4 beats/min). After isoprenaline...

...J.-F. Liard 1. We have studied whether the progressive rise in peripheral resistance observed in response to chronic intracoronary administration of dobutamine in conscious dogs could have resulted from extracardiac or non-β-adrenergic cardiac effects of the drug. 2. Six conscious dogs received...

...J.-F. Liard 1. In order to determine if a sustained increase in cardiac output can lead to hypertension, seven conscious dogs were given a continuous infusion of dobutamine, a powerful stimulant of cardiac inotropism, into the left coronary artery for a 7 day period while arterial pressure, cardiac...