...Ehud Grossman; Aaron Hoffman; Ines Armando; Zaid Abassi; Irwin J. Kopin; David S. Goldstein 1. To determine the sources of dopa (3,4-dihydroxyphenylalanine) in plasma, we measured regional arteriovenous differences, tissue concentrations and urinary excretion of dopa during systemic intravenous...

...Ehud Grossman; Aaron Hoffman; Peter C. Chang; Harry R. Keiser; David S. Goldstein 1. We measured urinary excretion rates of dopamine (3,4-dihydroxyphenethylamine) and dopa (3,4-dihydroxyphenylalanine) and the spillover rate of dopa into arterial blood during dietary salt loading in conscious Dahl...

...Reuven Zimlichman; Paul D. Levinson; Gerald Kelly; Robin Stull; Harry R. Keiser; David S. Goldstein 1. We estimated the extent to which circulating dopa (3,4-dihydroxyphenylalanine) is the source of urinary dopamine (DA; 3,4-dihydroxyphenethylamine). Tritiated dopa ([ 3 H]dopa) was infused for 90...

... acids l -dopa ( l -3,4-dihydroxyphenylalanine) and 5-hydroxytryptophan. During the final two clearance periods, the peripheral decarboxylase inhibitor, carbidopa ( S -α-hydrazino-3,4-dihydroxy-α-methylbenzenepropanoic acid monohydrate), was infused additionally. 2. Renal formation of dopamine (3,4...

...S. G. Ball; I. G. Gunn; K. J. D. Macarthur; I. H. S. Douglas; G. C. Inglis 1. Plasma levels of dopa, dopamine, noradrenaline and adrenaline were measured in blood sampled from the renal vein and from the aorta at the origin of the renal artery in six anaesthetized greyhound dogs. 2. Plasma levels...

...W. Januszewicz; B. Wocial 1. Urinary excretion of dopa, catecholamines and their metabolites (vanillylmandelic acid, methoxycatecholamines, 3-methoxy-4-hydroxyphenylglycol and homovanillic acid) were studied in eighty patients with essential hypertension and in twenty-five healthy control subjects...