... © The Authors Journal compilation © 2014 Biochemical Society 2014 cardiovascular disease diabetes dyslipidaemia hypertension microRNA (miRNA) miRNAs (microRNAs) are short (~19–25 nucleotides in length) single-stranded non-encoding RNAs that are well conserved in eukaryotic...

... with the significant rise in PCSK9 levels after statin therapy, warrant further studies in order to unravel the exact role of PCSK9 in the pathogenesis and treatment of this highly prevalent genetic dyslipidaemia. In addition, a subgroup of FCHL patients ( n =11) also visited our clinic before and after 8 weeks...

...Sandra J. Hamilton; Gerard T. Chew; Timothy M.E. Davis; Gerald F. Watts Dyslipidaemia contributes to endothelial dysfunction and CVD (cardiovascular disease) in Type 2 diabetes mellitus. While statin therapy reduces CVD in these patients, residual risk remains high. Fenofibrate corrects atherogenic...

...Esther M. M. Ooi; P. Hugh R. Barrett; Dick C. Chan; Gerald F. Watts The concurrence of visceral obesity, insulin resistance and dyslipidaemia comprises the concept of the metabolic syndrome. The metabolic syndrome is an escalating problem in developed and developing societies that tracks...

... of this relationship has not been examined in detail in patients with dyslipidaemia. The present study examines the variance of non-HDL-C compared with apoB in 1771 consecutive patients evaluated in a lipid clinic. These patients were divided into normolipidaemic subjects ( n =407), type I hyperlipoproteinaemia ( n...

... adipose tissue aging apolipoprotein B (apoB) body mass index dyslipidaemia familial combined hyperlipidaemia (FCH) obesity The study population consisted of kindreds of families with known FCH recruited in 1994, 1999 or 2004 and followed up in 1999 and/or 2004 [ 6 , 16 , 17 ]. All FCH kindreds...

.... Our findings suggest that in subjects with the MS alterations in cholesterol absorption and synthesis may be closely linked with the kinetic defects in TRL metabolism. breath test campesterol cholesterol absorption chylomicron remnant metabolism dyslipidaemia Correspondence: Dr Dick C...

...-dependent diabetes mellitus uncomplicated by overt hypertension or microproteinuria. Endothelial dysfunction may be related to diabetic dyslipidaemia and associated metabolic disturbances. Clinical Science ( I 996) 9 I, 567-573 (Printed in Great Britain) 567 Impaired endothelium-dependent and independent...