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Keywords: emphysema
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Clin Sci (Lond) (2019) 133 (8): 983–996.
Published: 29 April 2019
... (COPD), but the underlying mechanisms are not well-known. Recently, we demonstrated that RV causes persistent lung inflammation with accumulation of a subset of macrophages (CD11b + /CD11c + ), and CD8 + T cells, and progression of emphysema. In the present study, we examined the mechanisms underlying...
Includes: Supplementary data
Clin Sci (Lond) (2014) 126 (4): 253–265.
Published: 14 October 2013
... cigarette smoke, causes progressive airflow limitation. This inflammation, where macrophages, neutrophils and T-cells are prominent, leads to oxidative stress, emphysema, small airways fibrosis and mucus hypersecretion. The mechanisms and mediators that drive the induction and progression of chronic...
Clin Sci (Lond) (1991) 80 (4): 353–358.
Published: 01 April 1991
...M. Gugger; G. Gould; M. F. Sudlow; P. K. Wraith; W. MaCnee 1. We assessed lung density, determined by computerized tomography, as a measure of emphysema and related this to lung function and measurement of the elastic recoil of the lung in normal subjects and patients with chronic obstructive lung...
Clin Sci (Lond) (1988) 75 (4): 415–420.
Published: 01 October 1988
... patients with emphysema and in 11 healthy controls. Whole-body protein turnover was measured using l -[1- 13 C]leucine. 2. Leg efflux of tyrosine was increased by 47% in emphysematous patients compared with normal control subjects, but 3-methylhistidine efflux was not significantly altered. 3. In emphysema...
Clin Sci (Lond) (1988) 75 (1): 53–62.
Published: 01 July 1988
.... 1 12 1987 22 12 1987 © 1970 The Biochemical Society and the Medical Research Society 1970 antileucoprotease elastase elastin emphysema myeloperoxidase polymorphonuclear leucocytes Clinical Science (1988) 75,53-62 53 Interactions among stimulated human polymorphonuclear...
Clin Sci (Lond) (1982) 62 (3): 311–319.
Published: 01 March 1982
...G. W. Bradley; T. Hale; J. Pimble; R. Rowlandson; M. I. M. Noble 1. The potential value of right vagotomy for the relief of breathlessness has been explored in five patients with emphysema. Two patients had symptomatic improvement, two had minor symptomatic improvement, and one was unchanged. 2...
Clin Sci Mol Med (1977) 53 (6): 587–593.
Published: 01 December 1977
...% of normal (331 ± 110 ml). There was therefore no correlation between the amount of emphysema and the reduction in pulmonary blood volume. CIinical Science and Molecular Medicine (1977) 53,587-593. Pulmonary blood volume in chronic bronchitis B. RAFFESTIN, H. VALETTE, J. L. HEBERT, P. DUHAZE AND A. LOCKHART...